Ariprazole

Ariprazole5 mg

Tablet

Aripiprazole

General Pharmaceuticals Ltd.

Product Code : 1273
MRP 35.20
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Medicine overview

Indications of Ariprazole 5 mg

Ariprazole 5 mg is indicated for- Schizophrenia Schizoaffective disorder Acute manic and mixed episodes associated with Bipolar I Disorder Maintaining efficacy in patients with Bipolar I Disorder who are stabilized

Theropeutic Class

Atypical neuroleptic drugs

Pharmacology

Ariprazole 5 mg is an atypical antipsychotic that has both dopamine and serotonin receptors activity. It is a partial agonist of dopamine D2 receptors that relieves the symptoms of schizophrenia. It is characterized as a dopamine system stabilizer. It is a potent partial agonist at serotonin 5-HT1A receptors and antagonist at 5-HT2A receptors. This is associated with improvement of depressive, cognitive and negative symptoms.

Dosage & Administration of Ariprazole 5 mg

For Schizophrenia: 10 to 15 mg, once daily, without regard to food. Dose increment should not be made before 2 weeks, the time needed to achieve steady state.For Bipolar mania: 30 mg, once daily, without regard to food.

Dosage of Ariprazole 5 mg

For Schizophrenia: 10 to 15 mg, once daily, without regard to food. Dose increment should not be made before 2 weeks, the time needed to achieve steady state.For Bipolar mania: 30 mg, once daily, without regard to food.

Interaction of Ariprazole 5 mg

Caution should be exercised when aripipazole is taken in combination with other centrally acting drugs and alcohol. Carbamazepine could cause an increase in Ariprazole 5 mg clearance and lower blood levels. Ketoconazole, quinidine, fluoxetine or paroxetine can inhibit Ariprazole 5 mg elimination and cause increased blood levels.

Contraindications

Ariprazole 5 mg is contraindicated in patients who are hypersensitive to it or to any component of this product.

Side Effects of Ariprazole 5 mg

Headache, constipation, asthenia, nausea, dyspepsia, vomiting, coughing, abdominal pain.

Pregnancy & Lactation

Ariprazole 5 mg should not be used in pregnancy as no human trial is performed. Patients should be advised not to breast feed an infant if they are taking Ariprazole 5 mg.

Precautions & Warnings

Ariprazole 5 mg may be associated with orthostatic hypotension (orthostatic lightheadedness).Ariprazole 5 mg should be used with caution in patients with known cardiovascular disease (myocardial infarction or ischaemic heart disease, heart failure or conduction abnormalities), cerebrovascular disease, or conditions that would predispose patients to hypotension (dehydration, hypovolemia, and treatment with antihypertensive medications).Seizures occurred in Ariprazole 5 mg-treated patients. As with other antipsychotic drugs, Ariprazole 5 mg should be used cautiously in patients with Alzheimer's dementia.Ariprazole 5 mg is not approved for the treatment of patients with dementia-related psychosis.

Overdose Effects of Ariprazole 5 mg

Ariprazole 5 mg at doses up to 1080 mg causes no fatalities. The signs and symptoms observed with Ariprazole 5 mg overdose included nausea, vomiting, asthenia, diarrhea, and somnolence.

Drug Classes

Atypical neuroleptic drugs

Mode Of Action

Ariprazole 5 mg is an atypical antipsychotic that has both dopamine and serotonin receptors activity. It is a partial agonist of dopamine D2 receptors that relieves the symptoms of schizophrenia. It is characterized as a dopamine system stabilizer. It is a potent partial agonist at serotonin 5-HT1A receptors and antagonist at 5-HT2A receptors. This is associated with improvement of depressive, cognitive and negative symptoms.

Pregnancy

Ariprazole 5 mg should not be used in pregnancy as no human trial is performed. Patients should be advised not to breast feed an infant if they are taking Ariprazole 5 mg.
Disclaimer

The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.