Ariprex

Ariprex2 mg

Tablet

Aripiprazole

Square Pharmaceuticals PLC.

Product Code : 1274
MRP 2.00
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Medicine overview

Indications of Ariprex 2 mg

Ariprex 2 mg is indicated for- Schizophrenia Schizoaffective disorder Acute manic and mixed episodes associated with Bipolar I Disorder Maintaining efficacy in patients with Bipolar I Disorder who are stabilized

Theropeutic Class

Atypical neuroleptic drugs

Pharmacology

Ariprex 2 mg is an atypical antipsychotic that has both dopamine and serotonin receptors activity. It is a partial agonist of dopamine D2 receptors that relieves the symptoms of schizophrenia. It is characterized as a dopamine system stabilizer. It is a potent partial agonist at serotonin 5-HT1A receptors and antagonist at 5-HT2A receptors. This is associated with improvement of depressive, cognitive and negative symptoms.

Dosage & Administration of Ariprex 2 mg

For Schizophrenia: 10 to 15 mg, once daily, without regard to food. Dose increment should not be made before 2 weeks, the time needed to achieve steady state.For Bipolar mania: 30 mg, once daily, without regard to food.

Dosage of Ariprex 2 mg

For Schizophrenia: 10 to 15 mg, once daily, without regard to food. Dose increment should not be made before 2 weeks, the time needed to achieve steady state.For Bipolar mania: 30 mg, once daily, without regard to food.

Interaction of Ariprex 2 mg

Caution should be exercised when aripipazole is taken in combination with other centrally acting drugs and alcohol. Carbamazepine could cause an increase in Ariprex 2 mg clearance and lower blood levels. Ketoconazole, quinidine, fluoxetine or paroxetine can inhibit Ariprex 2 mg elimination and cause increased blood levels.

Contraindications

Ariprex 2 mg is contraindicated in patients who are hypersensitive to it or to any component of this product.

Side Effects of Ariprex 2 mg

Headache, constipation, asthenia, nausea, dyspepsia, vomiting, coughing, abdominal pain.

Pregnancy & Lactation

Ariprex 2 mg should not be used in pregnancy as no human trial is performed. Patients should be advised not to breast feed an infant if they are taking Ariprex 2 mg.

Precautions & Warnings

Ariprex 2 mg may be associated with orthostatic hypotension (orthostatic lightheadedness).Ariprex 2 mg should be used with caution in patients with known cardiovascular disease (myocardial infarction or ischaemic heart disease, heart failure or conduction abnormalities), cerebrovascular disease, or conditions that would predispose patients to hypotension (dehydration, hypovolemia, and treatment with antihypertensive medications).Seizures occurred in Ariprex 2 mg-treated patients. As with other antipsychotic drugs, Ariprex 2 mg should be used cautiously in patients with Alzheimer's dementia.Ariprex 2 mg is not approved for the treatment of patients with dementia-related psychosis.

Overdose Effects of Ariprex 2 mg

Ariprex 2 mg at doses up to 1080 mg causes no fatalities. The signs and symptoms observed with Ariprex 2 mg overdose included nausea, vomiting, asthenia, diarrhea, and somnolence.

Drug Classes

Atypical neuroleptic drugs

Mode Of Action

Ariprex 2 mg is an atypical antipsychotic that has both dopamine and serotonin receptors activity. It is a partial agonist of dopamine D2 receptors that relieves the symptoms of schizophrenia. It is characterized as a dopamine system stabilizer. It is a potent partial agonist at serotonin 5-HT1A receptors and antagonist at 5-HT2A receptors. This is associated with improvement of depressive, cognitive and negative symptoms.

Pregnancy

Ariprex 2 mg should not be used in pregnancy as no human trial is performed. Patients should be advised not to breast feed an infant if they are taking Ariprex 2 mg.
Disclaimer

The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.