Beklo100 ml

Oral Solution


Opsonin Pharma Ltd.

Product Code : 1993
MRP 100.00
10% Off
Best PriceTk

Medicine overview

Indications of Beklo 100 ml

Beklo 100 ml is indicated for the treatment of spasticity, including flexor spasms, associated pain, clonus, muscular rigidity, as well as skeletal muscle spasms resulting from conditions such as multiple sclerosis, rheumatic disorders, spinal cord injuries, other spinal cord diseases, cerebrovascular accidents, neoplastic, or degenerative brain diseases.

Theropeutic Class

Centrally acting Skeletal Muscle Relaxants


Beklo 100 ml is an effective muscle relaxant and antispastic agent that primarily acts at the spinal level. While its exact mode of action is not fully understood, Beklo 100 ml works by stimulating GABAB receptors, which inhibits the release of glutamate and aspartate, thereby affecting both monosynaptic and polysynaptic reflexes.

It may also have central nervous system (CNS) depressant effects at intraspinal sites. Notably, Beklo 100 ml does not impact neuromuscular transmission. Beklo 100 ml exhibits an antinociceptive (pain-relieving) effect, although its clinical significance remains uncertain.

Dosage & Administration of Beklo 100 ml

Beklo 100 ml should be taken with a small amount of liquid during meals. The dosing regimen for Beklo 100 ml varies for adults and children.

In adults, it's typically administered in divided doses, preferably three times a day. The aim is to use the lowest effective dose.

For adults, the therapy usually begins with a low dose and is then increased gradually to achieve the best response, typically falling within the range of 30-80 mg daily. Additional increases may be necessary but should generally not exceed a maximum daily dose of 80 mg.

For children, treatment should begin with an extremely low dose, such as 0.3 mg/kg per day, divided into multiple doses. The dose can then be cautiously increased at 1-2 week intervals until it meets the child's specific needs.

The usual maintenance dose for children typically falls within the range of 0.75 to 2 mg/kg of body weight per day.

For children over 10 years of age, a maximum daily dose of 2.5 mg/kg of body weight may be considered.

Interaction of Beklo 100 ml

Increased sedation may occur when Beklo 100 ml is taken alongside agents that affect the central nervous system, alcohol, or synthetic opiates. This also elevates the risk of respiratory depression. When Beklo 100 ml is combined with antihypertensives, it's likely to amplify the drop in blood pressure. Adjustments to the antihypertensive medication dosage may be necessary. 

Concurrently administering Beklo 100 ml with tricyclic antidepressants may intensify Beklo 100 ml's pharmacological effects, leading to pronounced muscular hypotonia. In individuals with Parkinson's disease receiving Beklo 100 ml along with levodopa and carbidopa, there have been reports of mental confusion, hallucinations, headaches, nausea, and agitation. 

When MAO inhibitors and Beklo 100 ml are used together, it may result in increased CNS depressant effects. Caution is advised, and the dosage of one or both agents should be adjusted accordingly. Care should also be taken when administering Beklo 100 ml in conjunction with magnesium sulfate or other neuromuscular blocking agents, as there is a theoretical potential for a synergistic effect.


Beklo 100 ml is contraindicated in patients with hypersensitivity to any component of this product.

Side Effects of Beklo 100 ml

The common adverse reactions associated with Beklo 100 ml include drowsiness, dizziness, weakness, and fatigue.

More serious adverse reactions are less common, but can occur. These include:

  • Central nervous system effects: headaches, insomnia, euphoria, excitement, depression, confusion, hallucinations, paraesthesia, nightmares, muscle pain, tinnitus, slurred speech, coordination disorders, tremors, rigidity, dystonia, ataxia, blurred vision, nystagmus, strabismus, miosis, mydriasis, diplopia, dysarthria, epileptic seizures, and respiratory depression.
  • Cardiovascular reactions: hypotension, dyspnoea, palpitations, chest pain, and syncope.
  • Gastrointestinal reactions: nausea, constipation, dry mouth, anorexia, taste disorders, abdominal pain, vomiting, diarrhea, and positive tests for occult blood in stool.
  • Genitourinary reactions: urinary frequency, enuresis, urinary retention, dysuria, impotence, inability to ejaculate, nocturia, and hematuria.
  • Other potential reactions: rash, pruritus, ankle edema, excessive perspiration, weight gain, nasal congestion, visual disturbances, hepatic function disorders, and a paradoxical increase in spasticity.

Muscular hypotonia, or low muscle tone, can also occur with Beklo 100 ml. This is usually relieved by adjusting the dosage.

Pregnancy & Lactation

Pregnancy category B3. The safety of using Beklo 100 ml during pregnancy has not been established, as it can cross the placental barrier. Administration to pregnant women should only occur when the physician concludes that the potential benefits outweigh the possible risks. Beklo 100 ml is excreted in breast milk, but available evidence suggests that the quantities are so minimal that no adverse effects on the infant are expected.

Precautions & Warnings

Lower doses (approximately 5 mg per day) should be considered for patients with impaired renal function or those undergoing chronic hemodialysis. Patients who not only have spasticity but also suffer from psychotic disorders, schizophrenia, depressive or manic disorders, or confusional states should be treated cautiously and closely monitored, as exacerbations of these conditions may occur. In patients with epilepsy and muscle spasticity, Beklo 100 ml may be used under appropriate supervision, provided that adequate anticonvulsive therapy is continued. It's important to note that lowering the convulsion threshold may occur, and seizures have been reported after the cessation of Beklo 100 ml therapy or in cases of overdose.

Caution should be exercised in patients with a history of peptic ulcers, cerebrovascular diseases, or hepatic, renal, or respiratory failure. Vigilant monitoring of respiratory and cardiovascular function is essential, especially in those with cardiopulmonary disease and respiratory muscle weakness. While Beklo 100 ml treatment may improve neurogenic disturbances affecting bladder emptying, individuals with preexisting sphincter hypertonia may experience acute retention of urine in these circumstances. It's important to note that Beklo 100 ml has not significantly benefited patients with stroke, and they have shown poor tolerance to the medication. For individuals with hepatic diseases or diabetes mellitus, appropriate laboratory tests should be conducted periodically to ensure that there are no medication-induced changes in these underlying conditions.

Overdose Effects of Beklo 100 ml

Gastric lavage is important in case of severe overdose.

Storage Conditions

Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.

Drug Classes

Centrally acting Skeletal Muscle Relaxants

Mode Of Action

Beklo 100 ml inhibits both monosynaptic and polysynaptic reflexes at the spinal level by stimulating the GABAB receptors, which in turn inhibits the release of glutamate and aspartate. Additionally, it may act at intraspinal sites, leading to CNS depression. Beklo 100 ml also demonstrates an antinociceptive effect.


The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.