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Benzac4%
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Brevoxyl4%
Cream
Benzoyl Peroxide
GlaxoSmithKline
Product Code : 2450
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Medicine overview
Indications of Brevoxyl 4%
Topical therapy for the treatment of acne vulgaris.
Theropeutic Class
Acne treatment preparations
Pharmacology
Benzoyl peroxide has mild keratolytic effect and antimicrobial activity due to release of free-radical oxygen which oxidizes bacterial protein. It is active against Staphylococcus epidermidis and Propionibacterium acnes.
Dosage & Administration of Brevoxyl 4%
Adult: As 2.5-10% preparation: Apply 1-2 times daily after cleansing, may gradually increase to tid if needed. Start with lower strength preparations. As cleanser: Wash 1-2 times daily.Child: ≥12 yr Same as adult dose.
Dosage of Brevoxyl 4%
Adult: As 2.5-10% preparation: Apply 1-2 times daily after cleansing, may gradually increase to tid if needed. Start with lower strength preparations. As cleanser: Wash 1-2 times daily.Child: ≥12 yr Same as adult dose.
Interaction of Brevoxyl 4%
There is no known interaction with other medications which might be used cutaneously and concurrently with Brevoxyl 4%; however, drugs with desquamative, irritant and drying effects should not be used concurrently with Brevoxyl 4% gel.
Contraindications
Brevoxyl 4% gel is contra-indicated in patients with known hypersensitivity to Brevoxyl 4%.
Side Effects of Brevoxyl 4%
The major adverse reaction reported to date with Brevoxyl 4% cutaneous therapy is irritation of the skin including erythema, burning, peeling, dryness, itching, stinging, feeling of skin tension locally at the site of application. This is reversible when treatment is reduced in frequency or discontinued. Allergic contact dermatitis, including face oedema, may occur.
Pregnancy & Lactation
Pregnancy Category C. Either studies in animals have revealed adverse effects on the fetus (teratogenic or embryocidal or other) and there are no controlled studies in women or studies in women and animals are not available. Drugs should be given only if the potential benefit justifies the potential risk to the fetus.
Precautions & Warnings
Children, Pregnancy and lactation.
Overdose Effects of Brevoxyl 4%
Brevoxyl 4% gel is a preparation indicated for topical treatment only. If the medication is applied excessively, no more rapid or better results will be obtained and severe irritation might develop. In this event, treatment must be discontinued and appropriate symptomatic therapy should be instituted.
Storage Conditions
Store in a cool and dry place, protected from light.
Drug Classes
Acne treatment preparations
Mode Of Action
Benzoyl peroxide has mild keratolytic effect and antimicrobial activity due to release of free-radical oxygen which oxidizes bacterial protein. It is active against Staphylococcus epidermidis and Propionibacterium acnes.
Pregnancy
Pregnancy Category C. Either studies in animals have revealed adverse effects on the fetus (teratogenic or embryocidal or other) and there are no controlled studies in women or studies in women and animals are not available. Drugs should be given only if the potential benefit justifies the potential risk to the fetus.
Disclaimer
The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.
