Defaz5 mg+20 mg

This tablet is indicated for the treatment and prophylaxis of Folic Acid and Zinc deficiencies.

Specific mineral & vitamin combined preparations

Zinc is an essential element in human health with a wide range of roles. It works as a coenzyme for more than 200 enzymes. These enzymes are involved in nucleic acid and protein metabolism and the production of energy. Zinc is vital for growth and development. Zinc deficiency can result in growth retardation, immune dysfunction, increased incidence of infections, anorexia, weight loss, neural tube defects of the foetus, increased risk for abortion and mental lethargy. Folic Acid is the member of B-vitamin group. Folic Acid participates in several key biological processes, including the synthesis of DNA, RNA and proteins. It is necessary for DNA replication and is involved in the regulation of gene expression. Folic Acid deficiency in pregnant women results in an increased incidence of neural tube defects, including meningomyelocele (e.g., spina bifida), anencephaly, meningocele and craniorachischisis in their neonates. Folic Acid deficiency leads to megaloblastic anemia. Other symptoms and signs of Folic Acid deficiency include weakness, fatigue, irritability, headache, difficulty concentrating, palpitations etc.

One tablet daily or as recommended by the physician.

Orally 1 tablet daily or as directed by the physician.

A large amount of Calcium decreases the absorption of Zinc. In case of Folic Acid, no drug interactions have been reported.

Zinc is contraindicated in patients having hypersensitivity to Zinc. Folic Acid is contraindicated in untreated cobalamine deficiency

Folic Acid & Zinc is well tolerated in the recommended dose. Occasionally gastrointestinal disturbances like abdominal pain, dyspepsia, nausea, vomiting, fever and respiratory distress may occur.

Use in pregnancy & lactation: Recommended

Zinc Sulfate is corrosive in overdose. Symptoms are corrosion and inflammation of the mucous membrane of the mouth and stomach.

Store at temperature of below 30°C, protect from light & moisture. Keep out of reach of children.

Specific mineral & vitamin combined preparations

This tablet is a special preparation of Folic Acid & Zinc Sulfate Monohydrate. Zinc is an essential trace element required for human nutrition and involved in a number of body enzyme system. Severe Zinc deficiency causes skin lesion, alopecia, diarrhoea, increased susceptibility of infections, cognitive impairment, etc. Folic Acid is a member of the B-Vitamins group. It is reduced in the body to tetrahydrofolate, which is the coenzyme for various metabolic processes including the synthesis of purine and pyrimidine nucleotides, and hence the synthesis of DNA. It is also involved in some amino acid conversions. Deficiency of Folic Acid may cause megaloblastic anaemia, develops when the dietary intake is inadequate, as in malnutrition, from malabsorption, from increased utilization as in pregnancy of conditions such as haemolytic anaemia, and as a result of administration of folate antagonists.

Recommended during pregnancy & lactation.