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Deslorin Plus

Deslorin Plus2.5 mg+120 mg

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Medicine overview

Indications of Deslorin Plus 2.5 mg+120 mg

This is indicated for the relief of the nasal and non-nasal symptoms of allergic rhinitis including nasal congestion.

Theropeutic Class

Anti-histamine & decongestant

Pharmacology

Desloratadine is a long-acting, tricyclic, non-sedating, selective peripheral histamine H1-receptor antagonist which inhibits the release of pro-inflammatory mediators from human mast cells and basophils.Pseudoephedrine is both an α-and β-adrenergic receptor agonist. It causes vasoconstriction via direct stimulation of α-adrenergic receptors of the respiratory mucosa. It also directly stimulates β-adrenergic receptors causing bronchial relaxation, increased heart rate and contractility.

Dosage & Administration of Deslorin Plus 2.5 mg+120 mg

Adults and children over 12 years of age: The recommended dose is Desloratadine 5 mg & Pseudoephedrine 240 mg tablet once daily or Desloratadine 2.5 mg & Pseudoephedrine 120 mg twice daily administered with or without a meal. In patients with renal impairment the dose may be given in every alternative day.

Interaction of Deslorin Plus 2.5 mg+120 mg

No specific interaction studies have been conducted with Desloratadine and Pseudoephedrine combination. However, Pseudoephedrine reduces the antihypertensive effects of beta-adrenergic blocking agents, methyldopa, mecamylamine, reserpine, and veratrum alkaloids. Increased ectopic pacemaker activity can occur when Pseudoephedrine is used concomitantly with digitalis.

Contraindications

Desloratadine and Pseudoephedrine combination is contraindicated in patients who are hypersensitive to this medication or to any of its ingredients, or to Desloratadine. Due to its Pseudoephedrine component, it is contraindicated in patients with narrow-angle glaucoma or urinary retention, and in patients receiving monoamine oxidase (MAO) inhibitor therapy or within fourteen (14) days of stopping such treatment. It is also contraindicated in patients with severe hypertension, severe coronary artery disease, and in those who have shown hypersensitivity or idiosyncrasy to its components, to adrenergic agents, or to other drugs of similar chemical structures.

Side Effects of Deslorin Plus 2.5 mg+120 mg

The common side effects are dry mouth, trouble sleeping, body aches or pain, hoarseness, weakness, restlessness, runny nose, sleepiness or unusual drowsiness, tender, swollen glands in neck, weight loss.

Pregnancy & Lactation

Desloratadine and Pseudoephedrine combination may be used in pregnancy or during lactation only if the potential benefit justifies the potential risk to the fetus or nursing infant.

Precautions & Warnings

This should be used with caution in patients with hypertension, diabetes mellitus, ischemic heart disease, increased intraocular pressure, hyperthyroidism or prostatic hypertrophy. Central nervous system stimulation with convulsions or cardiovascular collapse with accompanying hypotension may be produced by sympathomimetic amines.

Storage Conditions

Store in a cool and dry place. Protect from light.

Use In Special Populations

It is not recommended for children under 12 years of age.

Frequently Asked Questions

What is Deslorin Plus 2.5 mg+120 mg used for?

This is indicated for the relief of the nasal and non-nasal symptoms of allergic rhinitis including nasal congestion.

What is the dosage of Deslorin Plus 2.5 mg+120 mg?

Adults and children over 12 years of age: The recommended dose is Desloratadine 5 mg & Pseudoephedrine 240 mg tablet once daily or Desloratadine 2.5 mg & Pseudoephedrine 120 mg twice daily administered with or without a meal. In patients with renal impairment the dose may be given in every alternative day.

What are the side effects of Deslorin Plus 2.5 mg+120 mg?

The common side effects are dry mouth, trouble sleeping, body aches or pain, hoarseness, weakness, restlessness, runny nose, sleepiness or unusual drowsiness, tender, swollen glands in neck, weight loss.

Who should not take Deslorin Plus 2.5 mg+120 mg?

Desloratadine and Pseudoephedrine combination is contraindicated in patients who are hypersensitive to this medication or to any of its ingredients, or to Desloratadine. Due to its Pseudoephedrine component, it is contraindicated in patients with narrow-angle glaucoma or urinary retention, and in patients receiving monoamine oxidase (MAO) inhibitor therapy or within fourteen (14) days of stopping …

What precautions should be taken with Deslorin Plus 2.5 mg+120 mg?

This should be used with caution in patients with hypertension, diabetes mellitus, ischemic heart disease, increased intraocular pressure, hyperthyroidism or prostatic hypertrophy. Central nervous system stimulation with convulsions or cardiovascular collapse with accompanying hypotension may be produced by sympathomimetic amines.

Is Deslorin Plus 2.5 mg+120 mg safe during pregnancy and breastfeeding?

Desloratadine and Pseudoephedrine combination may be used in pregnancy or during lactation only if the potential benefit justifies the potential risk to the fetus or nursing infant.

Disclaimer

The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.

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