medEasy MedEasy
Product gallery

Epam5 mg

Tablet

Nitrazepam
ByOpsonin Pharma Ltd.
MRP ৳ 0.7510 % Off
Best PriceTk 0.68/piece
Out Of Stock
1
Section

Medicine overview

Indications of Epam 5 mg

Short-term management of insomnia, Infantile spasms

Theropeutic Class

Benzodiazepine hypnotics

Pharmacology

Epam 5 mg is a benzodiazepine with a pronounced sleep-inducing activity. It depresses the reticular-activating system in the brainstem by enhancing the inhibitory effect of GABA on brain cells, thus preventing excessive brain activity.

Dosage of Epam 5 mg

Short-term management of insomnia: Adult: 5 mg at night; increase to 10 mg if necessary. Elderly: and debilitated patients: ≤normal adult dose. Infantile spasms: Child: Infants: 125 mcg/kg bid; gradually increase to 250-500 mcg/kg bid.

Administration of Epam 5 mg

May be taken with or without food

Interaction of Epam 5 mg

CNS depressant effect increased with alcohol, barbiturates, TCAs, phenothiazines, morphine derivatives. Effects may be antagonised by theophylline. Increased levels/effects with probenecid. Reduced levels/effects with rifampicin. May reduce effects of levodopa.

Contraindications

Myasthenia gravis, narrow-angle glaucoma, severe respiratory insufficiency, sleep apnoea syndrome, severe hepatic impairment, porphyria.

Side Effects of Epam 5 mg

Hypotension, palpitation; agitation, aggressiveness, amnesia, ataxia, confusion, delusions, disorientation, dizziness, fatigue, hallucination, hangover, headache, irritability, nightmares, psychoses, rage, restlessness, sedation; rash; changes in libido; constipation, diarrhoea, excessive salivation, heartburn, nausea, vomiting; granulocytopenia, leukopenia; falling, muscle weakness; blurred or double vision; tinnitus (associated with withdrawal); aspiration, increased bronchial secretion, dyspnoea.

Pregnancy & Lactation

Category not classified

Precautions & Warnings

May induce anterograde amnesia; caution patients to have uninterrupted sleep of 7-8 hr after ingestion of dose. May impair ability to drive or operate machinery. Depression, especially if suicidal risk may be present. History of drug abuse or acute alcoholism. Hepatic and renal impairment. Respiratory disease. Debilitated patients. Patients who are at risk of falls. Children, elderly. Pregnancy and lactation.

Overdose Effects of Epam 5 mg

Symptoms: Somnolence, drowsiness, confusion, ataxia, impaired reflexes, coma, dyspnoea, hypotension, respiratory and cardiovascular depression. Management: Supportive. Gastric lavage may be beneficial if performed soon after ingestion. Flumazenil may reverse benzodiazepine-induced CNS depression.

Storage Conditions

Store at room temperature. Protect from light and moisture.

Drug Classes

Benzodiazepine hypnotics

Mode Of Action

Epam 5 mg is a benzodiazepine with a pronounced sleep-inducing activity. It depresses the reticular-activating system in the brainstem by enhancing the inhibitory effect of GABA on brain cells, thus preventing excessive brain activity.

Pregnancy

Category not classified

Frequently Asked Questions

What is Epam 5 mg used for?

Short-term management of insomnia, Infantile spasms

What is the dosage of Epam 5 mg?

Short-term management of insomnia: Adult: 5 mg at night; increase to 10 mg if necessary. Elderly: and debilitated patients: ≤normal adult dose. Infantile spasms: Child: Infants: 125 mcg/kg bid; gradually increase to 250-500 mcg/kg bid.

What are the side effects of Epam 5 mg?

Hypotension, palpitation; agitation, aggressiveness, amnesia, ataxia, confusion, delusions, disorientation, dizziness, fatigue, hallucination, hangover, headache, irritability, nightmares, psychoses, rage, restlessness, sedation; rash; changes in libido; constipation, diarrhoea, excessive salivation, heartburn, nausea, vomiting; granulocytopenia, leukopenia; falling, muscle weakness; blurred or do…

Who should not take Epam 5 mg?

Myasthenia gravis, narrow-angle glaucoma, severe respiratory insufficiency, sleep apnoea syndrome, severe hepatic impairment, porphyria.

What precautions should be taken with Epam 5 mg?

May induce anterograde amnesia; caution patients to have uninterrupted sleep of 7-8 hr after ingestion of dose. May impair ability to drive or operate machinery. Depression, especially if suicidal risk may be present. History of drug abuse or acute alcoholism. Hepatic and renal impairment. Respiratory disease. Debilitated patients. Patients who are at risk of falls. Children, elderly. Pregnancy an…

Is Epam 5 mg safe during pregnancy and breastfeeding?

Category not classified

Disclaimer

The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.

Home