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Feverin

Feverin100 mg

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Medicine overview

Indications of Feverin 100 mg

Feverin 100 mg is indicated in acute painextra-articular disordersosteoarthritispost-op painprimary dysmenorrhoea

Theropeutic Class

Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Pharmacology

Feverin 100 mg is a nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, anti-pyretic, and analgesic properties.

Absorption

Its cyclooxygenase inhibiting potency is intermediate, but is relatively selective for the cyclo-oxygenase-2 (COX-2) thus the potential for gastric injury and intolerance is less.

Distribution

It is also a free radical scavenger, and helps protect against the tissue damage that occurs during inflammation.

Excretion

It is also a free radical scavenger, and helps protect against the tissue damage that occurs during inflammation.

Dosage & Administration of Feverin 100 mg

100 mg twice daily. Should be taken with food. Take after meals.

Dosage of Feverin 100 mg

100 mg twice daily. Should be taken with food. Take after meals.

Interaction of Feverin 100 mg

Additive hepatotoxic effects with known hepatotoxins: anti-convulsants (e.g. valproic acid), anti-fungals (e.g. ketoconazole), anti-tuberculous drugs (e.g. isoniazid), tacrine, pemoline, amiodarone, methotrexate, methyldopa, amoxicillin/clavulanic acid. May decrease the oral bioavailability of furosemide and the natriuretic and diuretic response to furosemide. Increased risks of GI and hepatic adverse effects with other NSAIDs, including aspirin. May increase anti-coagulant effect of warfarin. Potentiates the action of phenytoin. May be displaced from binding sites with fenofibrate, salicylic acid, and tolbutamide. Interactions between NSAIDs and lithium, probenecid and ciclosporin, have been documented.

Contraindications

Hypersensitivity; GI bleeding, active peptic ulcer disease; severe renal and heart failure; hepatic impairment or known liver disease; coagulation disorders; pregnancy; children <12 yr.

Side Effects of Feverin 100 mg

Epigastric discomfort, heartburn or abdominal cramps, nausea, vomiting and diarrhoea; skin rash, pruritus, oedema, headache, dizziness, drowsiness; hypersensitivity reactions (e.g. bronchospasm, rhinitis, angioedema urticaria); GI haemorrhage/perforation; bullous/erosive stomatitis, purpura, thrombocytopenia, toxic epidermal necrolysis, haematuria, oliguria, and renal failure; increases in liver enzymes.

Pregnancy & Lactation

Category not classified

Precautions & Warnings

History of GI tract disease, infections, oedema, hypertension, elderly, lactation.

Overdose Effects of Feverin 100 mg

Epigastric pain, nausea, vomiting, drowsiness, lethargy, GI haemorrhage, seizures, hypertension, apnoea, coma, anaphylactic reactions and renal failure. Treatment is supportive.

Storage Conditions

Protect from heat and humidity; store at <25°C.

Drug Classes

Non-steroidal Anti-inflammatory Drugs (NSAIDs)

Mode Of Action

Feverin 100 mg is a nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, anti-pyretic, and analgesic properties. It inhibits prostaglandin synthetase/cyclooxygenase, which limits prostaglandin production. Its cyclooxygenase inhibiting potency is intermediate, but is relatively selective for the cyclo-oxygenase-2 (COX-2) thus the potential for gastric injury and intolerance is less. It is also a free radical scavenger, and helps protect against the tissue damage that occurs during inflammation.

Pregnancy

Category not classified

Frequently Asked Questions

What is Feverin 100 mg used for?

Nimesulide is indicated in acute pain; extra-articular disorders; osteoarthritis; post-op pain; primary dysmenorrhoea

What is the dosage of Feverin 100 mg?

100 mg twice daily. Should be taken with food. Take after meals.

What are the side effects of Feverin 100 mg?

Epigastric discomfort, heartburn or abdominal cramps, nausea, vomiting and diarrhoea; skin rash, pruritus, oedema, headache, dizziness, drowsiness; hypersensitivity reactions (e.g. bronchospasm, rhinitis, angioedema urticaria); GI haemorrhage/perforation; bullous/erosive stomatitis, purpura, thrombocytopenia, toxic epidermal necrolysis, haematuria, oliguria, and renal failure; increases in liver e…

Who should not take Feverin 100 mg?

Hypersensitivity; GI bleeding, active peptic ulcer disease; severe renal and heart failure; hepatic impairment or known liver disease; coagulation disorders; pregnancy; children <12 yr.

What precautions should be taken with Feverin 100 mg?

History of GI tract disease, infections, oedema, hypertension, elderly, lactation.

Is Feverin 100 mg safe during pregnancy and breastfeeding?

Category not classified

Disclaimer

The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.

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