Fibogel

Fibogel3.5 gm/5.4 gm

Effervescent Powder

Ispaghula Husk

Radiant Pharmaceuticals Ltd.

Product Code : 6782
MRP 415.00
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Medicine overview

Indications of Fibogel 3.5 gm/5.4 gm

This medicine contains Fibogel 3.5 gm/5.4 gm which is a bulking agent. This means that when it is taken with water it increases the size of the faeces (stools) and helps solid waste to pass through the body. Fibogel 3.5 gm/5.4 gm sachets are used to treat constipation and in conditions where it is better for the patient to have soft stools. They are also used for patients who require a high fibre diet

Theropeutic Class

Bulk-forming laxatives

Pharmacology

Most of the Ispaghula reach the caecum within four hours after ingestion in an intact and highly polymerized form. Ispaghula husk significantly increases the level of stool moisture, as well as wet and dry stool weight and shorten gastrointestinal transit time. Anaerobic fermentation of the soluble non-starch polysaccharides from Ispaghula seed results in the production of short chain fatty acids, acetate, propionate and butyrate in the intestine. Butyric acid is the preferred oxidative substrate for colonocytes and may be helpful in the treatment of ulcerative colitis. Ispaghula has hypocholesterolemic effects also. It is assumed that Ispaghula increases the activity of cholesterol alpha hydroxylase, HMG-CoA reductase and fractional turnover of both chenodeoxycholic and cholic acids. As a result it decreases cholesterol absorption and lowers LDL cholesterol.

Dosage of Fibogel 3.5 gm/5.4 gm

Constipation: Adult: 3.5 g 1-3 times daily. Mix with a full glass of liq. Child: ≤12 yr Each level 5-mL spoonful contains 1.75 g: Half to 1 level 5-mL spoonful bid (morning and evening) to be dissolved in water. Mild to moderate hypercholesterolaemia: Adult: As adjunct to lipid-lowering diet: 7.5-10 g daily. Mix with a full glass of liq.

Administration of Fibogel 3.5 gm/5.4 gm

Should be taken on an empty stomach. Take before meals with a full glass of water.

Interaction of Fibogel 3.5 gm/5.4 gm

Concurrent use of licorice, laxatives and antidiabetic agents may result in increased risk of hypokalemia and hypoglycemia. Carbamazepine bio-availability may be reduced during concomitant administration of psyllium seed.

Contraindications

Pre-existing faecal impaction, intestinal obstruction, natural or drug-induced reduction of gut motility, colonic atony e.g. senile megacolon.

Side Effects of Fibogel 3.5 gm/5.4 gm

Abdominal distention, flatulence, GI impaction, GI obstruction, hypersensitivity reactions e.g. rhinitis, conjunctivitis, bronchospasm and anaphylaxia; cutaneous symptoms (e.g. exanthema and/or pruritus).

Pregnancy & Lactation

No adverse effects of has been reported in pregnancy & lactation.

Precautions & Warnings

Patient with swallowing difficulty. Children.

Overdose Effects of Fibogel 3.5 gm/5.4 gm

Symptoms: Abdominal discomfort and flatulence. Management: Maintain adequate fluid intake.

Storage Conditions

Store below 30° C.
Disclaimer

The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.