Laxenna12 mg
Tablet
Sennosides
GlaxoSmithKline
Product Code : 9295
10% Off
Best PriceTk
/
1
Medicine overview
Indications of Laxenna 12 mg
It is used to treat hard stools (constipation).
Theropeutic Class
Osmotic purgatives
Pharmacology
Senna glycoside, also known as sennoside or senna, is a medication used to treat constipation and empty the large intestine before surgery. The medication is taken by mouth or via the rectum. It typically begins working in minutes when given by rectum and within twelve hours when given by mouth. It is a weaker laxative than bisacodyl or castor oil.Laxenna 12 mg A and B increase intestinal motility through release of active anthraquinones into the colon by colonic bacteria. Purified Laxenna 12 mg (Laxenna 12 mg A and B) are used similarly to senna.
Dosage & Administration of Laxenna 12 mg
Constipation
Adult: 15-30 mg (as total Laxenna 12 mg) 1-2 times daily.
Child: 2-6 yr: 3.75-7.5 mg once daily in the morning; 6-12 yr: 7.5-15 mg once daily at night or in the morning; ≥12 yr: 15-30 mg at bedtime.
Bowel evacuation
Adult: 105-157.5 mg of Laxenna 12 mg on the day before the procedure. May be given as a liquid preparation.
Dosage of Laxenna 12 mg
Constipation
Adult: 15-30 mg (as total Laxenna 12 mg) 1-2 times daily.
Child: 2-6 yr: 3.75-7.5 mg once daily in the morning; 6-12 yr: 7.5-15 mg once daily at night or in the morning; ≥12 yr: 15-30 mg at bedtime.
Bowel evacuation
Adult: 105-157.5 mg of Laxenna 12 mg on the day before the procedure. May be given as a liquid preparation.
Contraindications
Nausea or vomiting, undiagnosed abdominal pain, intestinal obstruction.
Side Effects of Laxenna 12 mg
Mild abdominal discomfort e.g. colic and cramps; diarrhoea, hypokalaemia and atonic non-functioning colon (prolonged use); reversible melanosis coli (chronic use). May colour the urine yellowish-brown at acidic pH or red at alkaline pH.
Pregnancy & Lactation
Laxenna 12 mg has been assigned to pregnancy category C by the FDA. Animal studies have failed to reveal evidence of teratogenicity. There are no controlled data in human pregnancy. Laxenna 12 mg should only be given during pregnancy when benefits outweigh risks.Laxenna 12 mg is not excreted into human milk. However, Laxenna 12 mg is a prodrug which is metabolized in vivo to the active Laxenna 12 mg (glucosides of rhein). Rhein is excreted into human milk in very small amounts. No adverse effects have been observed in nursing infants. The American Academy of Pediatrics considers Laxenna 12 mg to be compatible with breast-feeding.
Precautions & Warnings
Inflammatory bowel disease. Avoid prolonged use.
Drug Classes
Osmotic purgatives
Mode Of Action
Senna glycoside, also known as sennoside or senna, is a medication used to treat constipation and empty the large intestine before surgery. The medication is taken by mouth or via the rectum. It typically begins working in minutes when given by rectum and within twelve hours when given by mouth. It is a weaker laxative than bisacodyl or castor oil.Laxenna 12 mg A and B increase intestinal motility through release of active anthraquinones into the colon by colonic bacteria. Purified Laxenna 12 mg (Laxenna 12 mg A and B) are used similarly to senna.
Pregnancy
Laxenna 12 mg has been assigned to pregnancy category C by the FDA. Animal studies have failed to reveal evidence of teratogenicity. There are no controlled data in human pregnancy. Laxenna 12 mg should only be given during pregnancy when benefits outweigh risks.Laxenna 12 mg is not excreted into human milk. However, Laxenna 12 mg is a prodrug which is metabolized in vivo to the active Laxenna 12 mg (glucosides of rhein). Rhein is excreted into human milk in very small amounts. No adverse effects have been observed in nursing infants. The American Academy of Pediatrics considers Laxenna 12 mg to be compatible with breast-feeding.
Disclaimer
The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.