Negaron30 mg
Tablet
Cinnarizine
Gaco Pharmaceuticals Ltd.
Product Code : 11483
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Medicine overview
Indications of Negaron 30 mg
It is mainly used for the symptomatic treatment of nausea and vertigo due to Meniere's disease and other labyrinthine disturbances and for the prevention and treatment of motion sickness. It is also used in the management of various vascular disorders.Cerebral circulatory disorders:... Read more
Theropeutic Class
Anti vertigo drugs
Pharmacology
Negaron 30 mg acts as an antihistamine, labyrinthine sedative and a peripheral antivasoconstrictor. Negaron 30 mg is a selective calcium antagonist, inhibiting the influx of Ca2+ intracellularly. It prevents the Ca2+ dependent contraction of arterial smooth muscle by inhibiting Ca2+ influx through smooth muscle calcium channels and thereby, improves vestibular symptoms and prevents peripheral arterial disease
Dosage & Administration of Negaron 30 mg
Usual adult dose: 15 to 30 mg three times daily.Children (5 to 12 years): Half of the adult dose.Motion sickness: A dose of 30 mg two hours before the start of the journey and 15 mg every 8 hours during the journey.Peripheral arterial diseases: 75 mg two or three times daily.
Interaction of Negaron 30 mg
No drug interactions have been seen with Negaron 30 mg when administered concomitantly with antihypertensives, diuretics, anticoagulants or hypoglycaemics.
Contraindications
There are no specific contraindications. It has been found to decrease blood pressure significantly. However, the drug should be used with reasonable caution in hypotensive patients.
Side Effects of Negaron 30 mg
Side effects such as somnolence and gastrointestinal disturbances are extremely rare. They are transient and may be readily prevented by achieving the optimal dosage gradually. Allergic skin reactions and fatigue have been reported on rare occasions. An aggravation or appearance of extrapyramidal symptoms has been reported extremely rarely in elderly people during prolonged therapy. The treatment should be reduced or stopped in such cases.
Pregnancy & Lactation
The safety of Negaron 30 mg in human pregnancy has not been established although studies in animals have not demonstrated teratogenic effects. Therefore, it is not advisable to administer Negaron 30 mg in pregnancy
Precautions & Warnings
Negaron 30 mg may cause drowsiness; patients affected in this way should not drive or operate machinery. Avoid alcoholic drink.
Storage Conditions
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.
Disclaimer
The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.