Zosert50 mg



Sun Pharmaceutical Ltd.

Product Code : 19022
MRP 6.02
8% Off
Best PriceTk

Medicine overview

Indications of Zosert 50 mg

Zosert 50 mg is indicated in Depressive illness, Obsessive-compulsive disorder, Post-traumatic stress disorder, Panic disorder

Theropeutic Class

SSRIs & related anti-depressant drugs


Zosert 50 mg has potent and selective inhibitory action on CNS neuronal reuptake of 5-HT resulting in increased 5-HT concentrations at the synaptic clefts, leading to facilitation of its sustained activity at the postsynaptic receptor sites. It ultimately results in an improvement of depression. Reduction of Serotonin turnover in brain by Zosert 50 mg is also another contributing fact implicated in its action. Its prolonged elimination half-life offers a benefit of once daily administration.

Dosage & Administration of Zosert 50 mg

Depressive illness: Adult: Initially 50 mg daily, increased if necessary by increments of 50 mg over several weeks to maximum 200 mg daily. Usual maintenance dose is 50 mg daily. Child and adolescent less than 18 years: Not recommended. Obsessive-compulsive disorder: Adult and adolescent over 13 years: Initially 50 mg daily, increased if necessary in steps of 50 mg over several weeks. Usual dose range is 50-200 mg daily. Child (6-12 years): Initially 25 mg daily, increased to 50 mg daily after 1 week, further increased if necessary in steps of 50 mg at intervals of at least 1 week (maximum 200 mg daily).  Post-traumatic stress disorder: Adult: Initially 25 mg daily, increased after 1 week to 50 mg daily; if response is partial and if drug is tolerated, dose can be increased in steps of 50 mg over several weeks to maximum 200 mg daily. Child and adolescent less than 18 years: Not recommended. 

Interaction of Zosert 50 mg

Potential effects of co-administration of drugs that are highly bound to plasma proteins- As Zosert 50 mg is tightly bound to plasma protein, the administration of Zosert 50 mg to a patient taking another drug which is tightly bound to protein, (e.g. warfarin, digitoxin) may cause a shift in plasma concentrations potentially resulting in an adverse effect. Conversely adverse effects may result from displacement of protein bound Zosert 50 mg by other tightly bound drugs. Zosert 50 mg may interact with other drugs such as Cimetidine, CNS active drugs like Diazepam, Hypoglycemic drugs, Atenolol etc.


Zosert 50 mg is contraindicated in patients with a known hypersensitivity to Zosert 50 mg or any of the excipients of drug.

Side Effects of Zosert 50 mg

Zosert 50 mg may cause side effects like upset stomach, diarrhoea, constipation, vomiting, dry mouth, loss of appetite, weight changes, drowsiness, dizziness, headache, pain, burning or tingling in the hands or feet, excitement, sore throat etc.

Pregnancy & Lactation

Pregnancy: Although animal studies did not provide any evidence of teratogenicity, the safety of Zosert 50 mg during human pregnancy has not been established. Lactation: Zosert 50 mg is known to be excreted in breast milk. Its effects on the nursing infant have not yet been established. If treatment with Zosert 50 mg is considered necessary, discontinuation of breast-feeding should be considered.

Precautions & Warnings

Precaution should be taken in case of liver problems, kidney diseases, seizures, heart problems and any allergies. This drug may cause dizziness or drowsiness. Caution should be taken in activities requiring alertness such as driving or using machinery. Caution is advised while using this product in the elderly because they may be more sensitive to the effects of the drug. Do not take this drug if you have taken monoamine oxidase inhibitor in the last five weeks.

Storage Conditions

Store at 25° C.

The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.