Indications of Carbolin 100 ml
Carbolin 100 ml is indicated for- Acute bronchitis, Chronic bronchitis, Bronchial asthma, Upper respiratory tract inflammation (pharyngitis, laryngitis), Cystic fibrosis Bronchiectasis, Pulmonary tuberculosis, Drainage in chronic sinusitis and pneumonia, Drainage in otitis media in children.
Theropeutic Class
Cough expectorants & mucolytics
Pharmacology
Carbolin 100 ml reduces goblet cell hyperplasia and therefore plays a role in the management of disorders characterised by abnormal mucous. Carbolin 100 ml loosens thick sputum effectively by reducing its viscosity and thereby helps to expectorate that mucus more easily from the respiratory tract. The mucolytic action happens in several mechanisms. It breaks the disulphide bonds, which cross-link certain glycoprotein molecules in the mucus, the mucus produced under the influence of Carbolin 100 ml has high sialomucin and low fucomucin content. This combined effect ultimately reduces the viscosity of the sputum and increases its volume.
Dosage & Administration of Carbolin 100 ml
Adult: Initially, 2.25 g daily in divided doses, then 1.5 g daily in divided doses as condition improves.Child: 2-5 year: 62.5-125 mg 4 times daily; 6-12 year 250 mg tid.Should be taken with food.
Dosage of Carbolin 100 ml
Adult: Initially, 2.25 g daily in divided doses, then 1.5 g daily in divided doses as condition improves.Child: 2-5 year: 62.5-125 mg 4 times daily; 6-12 year 250 mg tid.Should be taken with food.
Interaction of Carbolin 100 ml
Neither hazardous nor therapeutically useful interactions have been reported.
Contraindications
Contraindicated in active peptic ulceration and in patients with hypersensitivity to the drug.
Side Effects of Carbolin 100 ml
Gastrointestinal discomfort, nausea, diarrhoea, gastrointestinal bleeding, palpitation, dizziness, headache, heartburn and skin rash may occur.
Pregnancy & Lactation
There is no information on the use of Carbolin 100 ml during lactation. While there are no reports of teratogenic effects, the manufacturers do not recommend the use of Carbolin 100 ml in the first trimester.
Precautions & Warnings
No specific precaution is recommended but Carbolin 100 ml should be used with caution in patients with a recent history of peptic ulcer and recurrent gastrointestinal bleeding.
Overdose Effects of Carbolin 100 ml
Symptoms: GI disturbance. Management: May perform gastric lavage, followed by observation.
Storage Conditions
Store in a cool and dry place protected from light.
Drug Classes
Cough expectorants & mucolytics
Mode Of Action
Carbolin 100 ml reduces goblet cell hyperplasia and therefore plays a role in the management of disorders characterised by abnormal mucous. Carbolin 100 ml loosens thick sputum effectively by reducing its viscosity and thereby helps to expectorate that mucus more easily from the respiratory tract. The mucolytic action happens in several mechanisms. It breaks the disulphide bonds, which cross-link certain glycoprotein molecules in the mucus, the mucus produced under the influence of Carbolin 100 ml has high sialomucin and low fucomucin content. This combined effect ultimately reduces the viscosity of the sputum and increases its volume.
Pregnancy
There is no information on the use of Carbolin 100 ml during lactation. While there are no reports of teratogenic effects, the manufacturers do not recommend the use of Carbolin 100 ml in the first trimester.