Indications of Clotzol 1%
The confirmed indication for Clotzol 1% include:
All dermatomycoses due to dermatophytes (e.g. Trichophyton species).
All dermatomycoses due to yeasts (Candida species).
Dermatomycoses due to moulds and other fungi.
Skin diseases showing superinfections with these fungi.
To the dermatomycoses listed under 1-4 belong for example, interdigital myocoses (e.g. athlete’s foot), paronychias (associated with nail mycoses), myocoses in skin folds, Candida vulvitis, Candida balanitis, Pityriasis versicolor, erythrasma.
Drugs for subcutaneous and mycoses, Topical Antifungal preparations
Clotzol 1% is a broad spectrum antifungal. It also exhibits activity against Trichomonus, Staphylococci, Streptococci and Bacteroides. Clotzol 1% kills fungi and yeasts by interfering with their cell membranes. It works by stopping the production of ergosterol, which is an essential component of fungal cell membranes resulting in increased membrane permeability and leakage of essential constituents of the fungal cells.
Dosage & Administration of Clotzol 1%
Wash skin with soap and water and dry thoroughly. Apply a thin layer of the cream or solution 2-3 times daily and gently massage over affected area as directed by the doctor. For Athlete’s foot, pay special attention to the spaces between the toes. Best results in Athlete's foot and ringworm are usually obtained with 4 weeks use of this product. The cream should be applied two or three times daily for one month or for at least two weeks after the disappearance of all signs of infection. If satisfactory results have not occurred within these times consultation with doctor is essential. For best results, follow directions and continue treatment for length of time indicated. The duration of treatment varies; it depends among other factors on the extent and localization of the disease.Recommended duration of treatment :
Dermatomycoses: 3-4 weeks
Candida vulvitis and candida balanitis: 1-2 weeks
Erythrasma and pityriasis versicolor (approx.): 3 weeks
In fungal infection of the feet, to prevent relapses: Treatment should be continued for about 2 weeks beyond the disappearance of all signs of disease.
Clotzol 1% cream is odourless, can be washed off and does not stain.
Hypersensitivity to Clotzol 1%.
Side Effects of Clotzol 1%
Clotzol 1% is generally well tolerated after local application but the few side effects have been reported infrequently like erythema, stinging, blistering, peeling, oedema, pruritus, urticaria and general irritation.
Pregnancy & Lactation
Pregnancy Category B. Clotzol 1% is recommended during pregnancy only after first consulting a doctor.Lactation: Because systemic absorption of Clotzol 1% following topical application is marginal, there should be no risk for the infant during lactation.
Precautions & Warnings
If local intolerance develops, consider withdrawal of the medicine and institution of appropriate therapy. Clotzol 1% solution is not intended for ophthalmic use.
Overdose Effects of Clotzol 1%
Supportive measures should be taken incase of accidental oral ingestion.
Store at a cool and dry place. Protect from light. Do not freeze.
Duration Of Treatment
For the treatment to become a complete success, reliable and sufficiently long application of Clotzol 1% cream is important. The duration of treatment varies; it depends among other factors on the extent and localisation of the disease.