Erdostin300 mg

Erdostin 300 mg is a mucolytic drug used in the treatment of acute and chronic respiratory diseases. It also improves the symptoms associated with short episodes of chronic bronchitis.

Cough expectorants & mucolytics

Erdostin 300 mg is a prodrug that is metabolised into N-thiodiglycolyl-homocysteine whereby free thiol groups are formed leading to the opening of the disulphide bonds of the bronchial mucoproteins, thus reducing the viscosity of mucus and purulent sputum. It also antagonises the local formation of free radicals and inhibits elastase enzyme activity and bacterial adhesion to epithelial cells.

The usual dose of elderly patients and adults above 18 years is 1 capsule twice daily for 10 days. But study shows that in chronic cases Erdostin 300 mg can be given up to 12 months or as directed by the physician. Erdostin 300 mg capsule may be taken with or without food.

The usual dose of elderly patients and adults above 18 years is 1 capsule twice daily for 10 days. But study shows that in chronic cases Erdostin 300 mg can be given up to 12 months or as directed by the physician. Erdostin 300 mg capsule may be taken with or without food.

It is contraindicated to patients who have hypersensitivity to Erdostin 300 mg. It should not be used in patients with creatinine clearance <25 ml/min, or with severe liver failure.

Common side effect is epigastric pain. Other side effects include headache, cold, taste alterations, nausea, vomiting, diarrhea, angioedema and other skin allergic reactions.

The use of Erdostin 300 mg in pregnant or breast-feeding women is not recommended.

It should be used with caution in mild liver failure. In that case, should not exceed a dose of 300 mg per day.

Keep in a dry place away from light and heat. Keep out of reach of children

Renal Impairment: CrCl <25 ml/min: Contraindicated.Hepatic Impairment: Mild to moderate: Max: 300 mg daily. Severe: Contraindicated.

Cough expectorants & mucolytics

Erdostin 300 mg is a prodrug that is metabolised into N-thiodiglycolyl-homocysteine whereby free thiol groups are formed leading to the opening of the disulphide bonds of the bronchial mucoproteins, thus reducing the viscosity of mucus and purulent sputum. It also antagonises the local formation of free radicals and inhibits elastase enzyme activity and bacterial adhesion to epithelial cells.

The use of Erdostin 300 mg in pregnant or breast-feeding women is not recommended.

Renal Impairment: CrCl <25 ml/min: Contraindicated.Hepatic Impairment: Mild to moderate: Max: 300 mg daily. Severe: Contraindicated.