Adgar0.1%
Gel
Adapalene
ACI Limited
Product Code : 314
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Medicine overview
Indications of Adgar 0.1%
Adgar 0.1% cream or gel is indicated for topical treatment of acne vulgaris.
Theropeutic Class
Topical retinoid and related preparations
Pharmacology
Adgar 0.1% acts on retinoid receptors that are commonly found in the skin of face, back and chest. Biochemical and pharmacological studies have demonstrated that Adgar 0.1% is a modulator of cellular differentiation, keratinization, and inflammatory processes, all of that represent important features in the pathology of acne vulgaris. Adgar 0.1% binds with specific retinoic acid nuclear receptors that normalize the differentiation of follicular epithelial cells resulting in decreased microcomedone formation. Absorption of Adgar 0.1% through human skin is low.
Dosage & Administration of Adgar 0.1%
Adgar 0.1% 0.1% cream: It should be applied to the affected areas of skin, once daily at night-time.Adgar 0.1% 0.3% gel: It should be applied to the entire face and any other affected areas of the skin, once daily in the evening.A thin film of gel or cream should be applied to the skin areas where lesions present, using enough to cover the entire affected areas lightly
Dosage of Adgar 0.1%
Adgar 0.1% 0.1%: It should be applied to the affected areas of skin, once daily at night-time.Adgar 0.1% 0.3%: It should be applied to the entire face and any other affected areas of the skin, once daily in the evening.Children below 12 years of age: Safety and effectiveness in children below 12 years of age have not been established.
Administration of Adgar 0.1%
A thin film of gel or cream should be applied to the skin areas where lesions present, using enough to cover the entire affected areas lightly.
Interaction of Adgar 0.1%
Concomitant use of other potentially irritating topical products (medicated or abrasive soaps and cleansers, soaps and cosmetics that have a strong drying effect, products with high concentrations of alcohol, astringents, spices or lime) should be approached with caution. Exercise particular caution in using preparations containing sulfur, resorcinol or salicylic acid in combination with Adgar 0.1%. If any of these preparations have been used, it is advisable not to start therapy with Adgar 0.1% until the effects of such preparations in skin have subsided. If combined use of both medications is important, it is better to use in two different times.
Contraindications
Adgar 0.1% should not be administered to individuals who are hypersensitive to Adgar 0.1% or any of its components.
Side Effects of Adgar 0.1%
Erythema, scaling, dryness, pruritus, burning sensation, skin irritation, stinging unburn, acne flares, etc. are commonly seen during the first month of therapy but usually lessen with continued use of the medication.
Pregnancy & Lactation
Use Adgar 0.1% during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is not known whether this drug is excreted in breast milk. Exercise caution when administering Adgar 0.1% to a nursing mother.
Precautions & Warnings
Adgar 0.1% should not be applied to cuts, abrasions, eczematous or sunburned skin.
Storage Conditions
Store in a cool (below 25°C) and dry place protected from light and moisture. Keep out of the reach of children. Keep the tube tightly closed after use.
Use In Special Populations
Safety and effectiveness in children below 12 years of age have not been established.
Drug Classes
Topical retinoid and related preparations
Mode Of Action
Adgar 0.1% acts on retinoid receptors that are commonly found in the skin of face, back and chest. Biochemical and pharmacological studies have demonstrated that Adgar 0.1% is a modulator of cellular differentiation, keratinization, and inflammatory processes, all of that represent important features in the pathology of acne vulgaris. Adgar 0.1% binds with specific retinoic acid nuclear receptors that normalize the differentiation of follicular epithelial cells resulting in decreased microcomedone formation. Absorption of Adgar 0.1% through human skin is low.
Pregnancy
Use Adgar 0.1% during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is not known whether this drug is excreted in breast milk. Exercise caution when administering Adgar 0.1% to a nursing mother.
Disclaimer
The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.