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Epinast0.05%
Aristopharma Ltd.
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Alpatin0.05%
Ophthalmic Solution
Epinastine Hydrochloride
Beximco Pharmaceuticals Ltd.
Product Code : 641
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Medicine overview
Indications of Alpatin 0.05%
Epinastine sterile ophthalmic solution is indicated for the treatment of signs and symptoms of allergic conditions of the anterior segment of the eye.
Theropeutic Class
Ophthalmic Non-Steroid drugs
Pharmacology
Epinastine is a topically active antihistamine that antagonizes both histamine H1 and H2 receptors. Moreover, it has mast cell stabilizing activity and prevents the release of inflammatory mediators from blood vessel. Epinastine does not penetrate the blood-brain barrier and therefore is not expected to induce side effects of the central nervous system.
Dosage & Administration of Alpatin 0.05%
The recommended dosage is one drop in each eye twice a day. Treatment should be continued throughout the period of exposure (i.e., until the pollen season is over or until exposure to the offending allergen is terminated), even when symptoms are absent.
Dosage of Alpatin 0.05%
Instill 1 drop in the affected eye(s) twice daily.
Contraindications
Contraindicated in patients who are hypersensitive to Epinastine or to any of the components of this preparation.
Side Effects of Alpatin 0.05%
The most frequently reported side effects are mild burning sensation, folliculosis, hyperemia, pruritus, cold symptoms and upper respiratory infections.
Pregnancy & Lactation
Use in pregnancy: There are no adequate and well-controlled studies in pregnant women. Epinastine should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Use in lactation: It is not known whether Epinastine is excreted in human milk. Caution should be exercised when Epinastine is administered to a nursing mother.
Precautions & Warnings
For ophthalmic use only. Patients should be advised not to wear contact lenses if their eye is red.
Storage Conditions
Store in a cool & dry place, protect from light. Do not use longer than one month after the first opening. Keep out of the reach of children.
Use In Special Populations
Pediatric Use: Safety and effectiveness in pediatric patients below the age of 3 years have not been established.Geriatric Use: No overall differences in safety or effectiveness have been observed between elderly and younger patients.
Drug Classes
Ophthalmic Non-Steroid drugs
Mode Of Action
Epinastine is a topically active antihistamine that antagonizes both histamine H1 and H2 receptors. Moreover, it has mast cell stabilizing activity and prevents the release of inflammatory mediators from the blood vessel. Epinastine does not penetrate the blood-brain barrier and therefore is not expected to induce side effects on the central nervous system.
Pregnancy
There are no adequate and well-controlled studies on pregnant women. Epinastine should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is not known whether Epinastine is excreted in human milk. Caution should be exercised when Epinastine is administered to a nursing mother.
Pediatric Uses
Use in children: Safety and effectiveness in children below the age of 3 years have not been established.Use in elderly patients: No overall differences in safety and effectiveness have been observed between elderly and other adult patients.
Disclaimer
The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.
