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Ambuterol5 mg/5 ml
Oral Solution
Bambuterol Hydrochloride
APC Pharma Ltd.
Product Code : 746
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Medicine overview
Indications of Ambuterol 5 mg/5 ml
Bambuterol is indicated for Bronchial asthma, chronic bronchitis, emphysema & other lung diseases where bronchospasm is a complicating factor.
Theropeutic Class
Short-acting selective & β2-adrenoceptor stimulants
Pharmacology
Bambuterol is an adrenergic β2 receptor agonist which predominantly stimulates β2 receptor, thus producing relaxation of bronchial smooth muscle, inhibition of release of endogenous spasmogens, inhibition of edema caused by endogenous mediators & increased mucocilliary clearance.
Dosage & Administration of Ambuterol 5 mg/5 ml
Adult or Elderly: The recommended initial dose 10 mg. The dose may be increased to 20 mg after 1-2 weeks depending on the clinical effect.Children 2-5 years: The recommended normal dose 10 mg (10 ml syrup).Children 6-12 years: The recommended normal dose 10 mg (10 ml syrup). The dose may be increased to 20 mg.
Dosage of Ambuterol 5 mg/5 ml
Adult or Elderly: The recommended initial dose 10 mg. The dose may be increased to 20 mg after 1-2 weeks depending on the clinical effect.Children 2-5 years: The recommended normal dose 10 mg (10 ml syrup).Children 6-12 years: The recommended normal dose 10 mg (10 ml syrup). The dose may be increased to 20 mg.
Interaction of Ambuterol 5 mg/5 ml
Succinylcholin, MAOIs (monoamine oxidase inhibitors), β2-blockers, corticosteroids, diuretics, muscle relaxants, sympathomimetic xanthine derivatives. Bambuterol may partly or totally inhibit the effect of β-blockers.
Contraindications
Bambuterol is contraindicated in hepatic impairment, liver cirrhosis or severely impaired liver function.
Side Effects of Ambuterol 5 mg/5 ml
Common side effects are fatigue, nausea, palpitation, headache, dizziness & tremor.
Pregnancy & Lactation
Pregnant women: There is no definite evidence of ill consequence during pregnancy. Nevertheless, the drug should not be used during the first trimester of pregnancy, unless the expected benefit is thought to outweigh any possible risk to the fetus.Lactating mother: It is excreted in breast milk. So, patients taking this drug should not breast-feed.
Precautions & Warnings
Reduce the dose in renal impairment, avoid in cirrhosis and severe hepatic impairment. Caution should be observed in patients with severe cardiovascular disorder, such as ischaemic heart disease, tachyarrhythmias or severe heart failure.
Storage Conditions
Keep away from light, store in a cool and dry place. Keep out of reach of children.
Use In Special Populations
Impaired renal function (GFR 50 ml/min): The recommended starting dose is 5 mg, which may be increased to 10 mg after one to two weeks, depending on the clinical effect.Impaired hepatic function: Not recommended because of unpredictable conversion to terbutaline.
Drug Classes
Short-acting selective & β2-adrenoceptor stimulants
Mode Of Action
Bambuterol is an adrenergic β2 receptor agonist which predominantly stimulates β2 receptor, thus producing relaxation of bronchial smooth muscle, inhibition of release of endogenous spasmogens, inhibition of edema caused by endogenous mediators & increased mucocilliary clearance.
Pregnancy
Pregnant women: There is no definite evidence of ill consequence during pregnancy. Nevertheless, the drug should not be used during the first trimester of pregnancy, unless the expected benefit is thought to outweigh any possible risk to the fetus.Lactating mother: It is excreted in breast milk. So, patients taking this drug should not breast-feed.
Pediatric Uses
Impaired renal function (GFR 50 ml/min): The recommended starting dose is 5 mg, which may be increased to 10 mg after one to two weeks, depending on the clinical effect.Impaired hepatic function: Not recommended because of unpredictable conversion to terbutaline.
Disclaimer
The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.
