Calamilon(15 mg+5 mg+5 mg)/100 ml

Calamilon is a topical skin-protectant and soothing lotion. It is an established over-the-counter preparation used for the symptomatic relief of:

• Minor skin irritation and itching (pruritus) from insect bites and stings
• Mild sunburn
• Prickly heat (miliaria)
• Minor irritation from poison ivy, oak, or sumac
• Mild, uncomplicated eczema flares as an adjunct soothing/protective measure alongside physician-directed treatment

Calamilon is intended only for temporary, symptomatic relief of minor and uncomplicated skin conditions; it is not a treatment for the underlying cause of infected, deeply inflamed, or broken skin.

Each preparation of Calamine + Zinc Oxide + Glycerine lotion typically contains Calamine 15% w/v, Zinc Oxide 5% w/v, and Glycerine (Glycerin) 5% w/v in an aqueous base (exact strengths may vary slightly by manufacturer/brand).

Calamilon is a fixed-dose topical combination lotion widely used as a mild astringent, antipruritic, and skin-protectant preparation. Calamine (a mixture of zinc oxide with a small amount of ferric oxide) and zinc oxide together form a protective film on the skin that has a mild drying and cooling effect, while glycerine acts as a humectant that keeps the skin and the applied film adequately moisturized, improving comfort and tolerability. Calamilon is applied externally and is not intended for internal use.

Calamilon belongs to the therapeutic class of topical skin protectants and astringent/antipruritic dermatological preparations.

Calamine + Zinc Oxide + Glycerine works through the combined physical and mild pharmacological actions of its components:

• Calamine has mild astringent and antipruritic properties; it helps dry weeping or oozing lesions and reduces the sensation of itching.
• Zinc Oxide forms a protective, mildly astringent barrier over the skin, shields irritated skin from further friction and moisture loss, and has weak antiseptic properties.
• Glycerine is a humectant that draws and retains moisture in the skin, preventing the applied lotion film from becoming excessively drying or causing cracking, and improves overall skin comfort.

Systemic absorption of Calamine + Zinc Oxide + Glycerine through intact skin is minimal, which accounts for its favorable safety profile.

Calamilon is for external (topical) use only. Clean and dry the affected area before application. Apply a thin layer and allow it to dry naturally; do not cover with an occlusive (airtight) dressing unless directed by a physician. Avoid contact with the eyes, mouth, nose, and other mucous membranes. Wash hands after application unless the hands are the area being treated.

Because systemic absorption of Calamilon from intact skin is minimal, clinically significant drug-drug interactions have not been well established.

• Avoid applying other topical medications, cosmetics, or products to the same skin area at the same time, as this may dilute the protective film, reduce effectiveness, or increase the risk of local irritation.
• If a physician has prescribed another topical medicine (e.g., a topical antibiotic or steroid) for the same area, space applications apart or seek specific guidance on sequencing from the prescriber.

Calamilon is generally very well tolerated, with minimal systemic absorption and a low overall risk profile. Reported effects include:

• Common (local, usually mild): transient stinging, dryness, or tightness of the skin at the application site.
• Uncommon: localized allergic contact dermatitis presenting as redness, rash, or increased itching at the site of application.
• Rare but serious: a hypersensitivity/allergic reaction with widespread rash, swelling of the face, lips, tongue, or throat, severe dizziness, or difficulty breathing — this requires immediate medical attention.

Stop using Calamilon and consult a physician if irritation worsens, spreads, or does not improve.

Calamilon has not been formally assigned an FDA pregnancy category, and systemic absorption through intact skin is expected to be minimal. As a general precaution, it should be used during pregnancy only if clearly needed, over limited areas, and after consulting a physician. During breastfeeding, avoid applying Calamilon to the nipple/areola area unless advised by a physician, to prevent inadvertent ingestion by the infant during feeding. In general, a physician or pharmacist should be consulted before use in pregnant or breastfeeding women.

Before using Calamilon, note the following precautions:

• For external use on intact skin only; do not apply to broken, deeply cut, infected, actively bleeding, or severely irritated skin, or to burns, without first consulting a physician.
• Avoid contact with the eyes, mouth, nasal passages, and other mucous membranes; if accidental contact occurs, rinse thoroughly with water.
• Shake well before use, as the lotion is a suspension that can separate on standing.
• Do not use as an occlusive dressing (i.e., under airtight bandages) unless directed by a physician.
• Discontinue use and seek medical advice if the condition worsens, does not improve within 7 days, or if signs of infection (increasing redness, warmth, swelling, pus, or fever) appear.
• Keep the container out of the reach of children; if accidentally swallowed, see Overdose Effects below.

Topical overdose of Calamilon is unlikely because it is applied externally in small amounts and systemic absorption is minimal. If a large amount is accidentally swallowed, especially by a child, seek immediate medical attention or contact a poison control center right away. Do not attempt to induce vomiting or give any home remedy unless specifically instructed by a medical professional or poison control service; treatment, if needed, will be supportive and symptomatic.

Store at room temperature (below 30°C), away from direct light and moisture. Keep the container tightly closed and shake well before each use. Keep out of the reach and sight of children.

Elderly: No dose adjustment is required; Calamilon may be used as in younger adults for the same indications.

Renal or hepatic impairment: Because systemic absorption from intact skin is minimal, dose adjustment is not expected to be necessary; however, caution and physician guidance are advised if used over large body surface areas.

Infants and young children: Use with caution; infants have a higher skin-surface-area-to-body-weight ratio, which can increase relative systemic absorption. Avoid applying over large areas, avoid occlusive dressings, and consult a physician before use in infants, particularly those under 2 years of age.

Calamilon is intended for short-term, symptomatic use, typically for up to about 7 days. If symptoms do not improve within this period, or if they worsen, discontinue use and consult a physician to rule out an underlying condition that requires specific treatment.

Calamine + Zinc Oxide + Glycerine is classified as a topical dermatological skin protectant, mild astringent, and antipruritic combination preparation.

Calamine + Zinc Oxide + Glycerine acts primarily through local, physical mechanisms rather than systemic pharmacology. Calamine and zinc oxide form a mild astringent, protective film over the skin surface that reduces oozing, cools the skin, and diminishes the itch sensation, while also creating a physical barrier against friction and minor irritants. Glycerine, as a humectant, draws moisture into this film and the underlying skin, preventing the preparation from drying the skin excessively and helping maintain the skin's natural barrier function during the healing process.

Calamilon is commonly used topically in children for minor skin irritation, itching, insect bites, and prickly heat. It should be applied only to intact skin over limited areas, and occlusive dressings should be avoided. Safety and efficacy for extensive or prolonged use in infants and very young children (particularly under 2 years of age) have not been formally established, and a physician should be consulted before use in this age group. Parents/caregivers should supervise application and keep the product out of the reach of children to prevent accidental ingestion.