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Clindacin300 mg
Incepta Pharmaceuticals Ltd.
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Clindax300 mg
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Medicine overview
Indications of Clindax 300 mg
Staphylococci and PneumococciUpper respiratory infectionsLower respiratory infectionsStaphylococci and PneumococciUpper respiratory infectionsLower respiratory infectionsSkin and soft tissue infectionsBone and joint infectionsPelvic infectionsIntra-abdominal infectionsSepticemia and endocarditis
Dosage of Clindax 300 mg
Dosage of Clindax 300 mg Capsule
Dosage:Serious Infections: 150 mg-300 mg every six hours
More severe infections
Dosage:300 mg-450 mg every six hours
Notes:To avoid the possibility of oesophageal irritation, Clindacin capsules should be taken with a full glass of water. Several researches has found that Clindax 300 mg 300 mg capsule provides plasma concentration over MIC90 for more than 12 hours. This finding supports the twice-daily dosing of Clindacin 300 mg capsule, particularly in SSTIs & RTIs. However, in case of bone & joint infections, diabetic foot infections dose of Clindax 300 mg should be 300 mg capsule 3-4 times daily
Dosage of Clindax 300 mg Powder for oral solution
Dosage:Serious infections: 8-12 mg/kg/day divided into 3 or 4 equal doses
Severe infections
Dosage:13-16 mg/kg/day divided into 3 or 4 equal doses
More severe infections
Dosage:17-25 mg/kg/day divided into 3 or 4 equal doses
Notes:In pediatric patients weighing 10 kg or less, 1/2 teaspoon (37.5 mg) three times a day should be considered the minimum recommended dose
Dosage of Clindax 300 mg IV/IM Injection
Dosage:Adults- Serious infections due to aerobic gram-positive cocci and the more susceptible anaerobes: 600-1200 mg/day in 2- 4 equal doses
More severe infections
Dosage:1200-2700 mg/day in 2-4 equal doses
For more serious infections
Dosage:these doses may have to be increased
Notes:In life-threatening situations due to either aerobes or anaerobes, these doses may be increased. Doses of as much as 4800 mg daily have been given intravenously to adults. Single intramuscular injections of greater than 600 mg are not recommended
Neonates (less than 1 month)
Dosage:15 to 20 mg/kg/day in 3 to 4 equal doses
Notes:The lower effective dosage may be adequate for small prematures
Pediatric patients (1 month of age to 16 years)
Dosage:20 to 40 mg/kg/day in 3 or 4 equal doses
Notes:The higher doses would be used for more severe infections. Parenteral therapy may be changed to Capsules (Clindax 300 mg hydrochloride) when the condition warrants and at the discretion of the physician. In cases of (3-hemolytic streptococcal infections, treatment should be continued for at least 10 days
| Condition | Dosage | Notes |
|---|---|---|
| Dosage of Clindax 300 mg Capsule | Serious Infections: 150 mg-300 mg every six hours | |
| More severe infections | 300 mg-450 mg every six hours | To avoid the possibility of oesophageal irritation, Clindacin capsules should be taken with a full glass of water. Several researches has found that Clindax 300 mg 300 mg capsule provides plasma concentration over MIC90 for more than 12 hours. This finding supports the twice-daily dosing of Clindacin 300 mg capsule, particularly in SSTIs & RTIs. However, in case of bone & joint infections, diabetic foot infections dose of Clindax 300 mg should be 300 mg capsule 3-4 times daily |
| Dosage of Clindax 300 mg Powder for oral solution | Serious infections: 8-12 mg/kg/day divided into 3 or 4 equal doses | |
| Severe infections | 13-16 mg/kg/day divided into 3 or 4 equal doses | |
| More severe infections | 17-25 mg/kg/day divided into 3 or 4 equal doses | In pediatric patients weighing 10 kg or less, 1/2 teaspoon (37.5 mg) three times a day should be considered the minimum recommended dose |
| Dosage of Clindax 300 mg IV/IM Injection | Adults- Serious infections due to aerobic gram-positive cocci and the more susceptible anaerobes: 600-1200 mg/day in 2- 4 equal doses | |
| More severe infections | 1200-2700 mg/day in 2-4 equal doses | |
| For more serious infections | these doses may have to be increased | In life-threatening situations due to either aerobes or anaerobes, these doses may be increased. Doses of as much as 4800 mg daily have been given intravenously to adults. Single intramuscular injections of greater than 600 mg are not recommended |
| Neonates (less than 1 month) | 15 to 20 mg/kg/day in 3 to 4 equal doses | The lower effective dosage may be adequate for small prematures |
| Pediatric patients (1 month of age to 16 years) | 20 to 40 mg/kg/day in 3 or 4 equal doses | The higher doses would be used for more severe infections. Parenteral therapy may be changed to Capsules (Clindax 300 mg hydrochloride) when the condition warrants and at the discretion of the physician. In cases of (3-hemolytic streptococcal infections, treatment should be continued for at least 10 days |
Interaction of Clindax 300 mg
Clindax 300 mg enhances the action of other neuromuscular blocking agents. Therefore, it should be used with caution in patients receiving such agents. Antagonism has been demonstrated between Clindax 300 mg and erythromycin in vitro. Because of possible clinical significance, these two drugs should not be administered concurrently.
Contraindications
Clindax 300 mg is contraindicated in patients previously found to be sensitive to Clindax 300 mg or any of the ingredients of this medicine.
Side Effects of Clindax 300 mg
The adverse effects have been reported with the use of Clindax 300 mg are- abdominal pain, oesophagitis and oesophagial ulcer, nausea, vomiting and diarrhoea, pruritus, skin rashes, urticaria.
Precautions & Warnings
Clindax 300 mg should be prescribed with caution in individuals with a history of gastrointestinal disease, particularly colitis.
Overdose Effects of Clindax 300 mg
Overdosage with orally administered Clindax 300 mg has been rare. Adverse reactions similar to those seen with normal doses can be expected, however, unexpected reactions could occur. Haemodialysis and peritoneal dialysis are not effective in removing Clindax 300 mg from the serum. Overdosage should be treated with simple gastric lavage. No specific antidote is known.
Storage Conditions
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.
Drug Classes
Macrolides
Pregnancy
Pregnancy Category B. Clindax 300 mg crosses the placenta in humans. After multiple doses, amniotic fluid concentrations were approximately 30% of maternal concentrations. Clindax 300 mg should be used in pregnancy only if clearly needed. Clindax 300 mg has been reported to appear in breast milk. Therefore, it is not recommended for nursing mothers if not clearly needed.
Pediatric Uses
Use in newborns and infants: When Clindax 300 mg is administered to newborns and infants (birth to 16 years), appropriate monitoring of organ system functions is desirable.Geriatric use: Dose adjustment of Clindax 300 mg is not necessary.
Frequently Asked Questions
What is Clindax 300 mg used for?
Clindamycin has been shown to be effective in the treatment of the following infections when caused by susceptible anaerobic bacteria or susceptible strains of gram positive bacteria such as Streptococci, Staphylococci and Pneumococci; Upper respiratory infections, Lower respiratory infections, Skin ... Read moreClindamycin has been shown to be effective in the treatment of the following infection…
What is the dosage of Clindax 300 mg?
Dosage of Clindamycin Capsule: Serious Infections: 150 mg-300 mg every six hours. More severe infections: 300 mg-450 mg every six hours. To avoid the possibility of oesophageal irritation, Clindacin capsules should be taken with a full glass of water.Several researches has found that Clindamycin 300 mg capsule provides plasma concentration over MIC90 for more than 12 hours. This finding supports t…
What are the side effects of Clindax 300 mg?
The adverse effects have been reported with the use of clindamycin are- abdominal pain, oesophagitis and oesophagial ulcer, nausea, vomiting and diarrhoea, pruritus, skin rashes, urticaria.
Who should not take Clindax 300 mg?
Clindamycin is contraindicated in patients previously found to be sensitive to clindamycin or any of the ingredients of this medicine.
What precautions should be taken with Clindax 300 mg?
Clindamycin should be prescribed with caution in individuals with a history of gastrointestinal disease, particularly colitis.
Disclaimer
The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.