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Colicon10 mg
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Medicine overview
Indications of Colicon 10 mg
Dicycloverine is indicated in:
Functional bowel/irritable bowel syndrome
Urinary incontinence secondary to unstable detrusor muscle
Infantile colic
GIT spasm
Colicky abdominal pain
Diverticulitis
Abdominal colic
Theropeutic Class
Anticholinergics (antimuscarinics)/ Anti-spasmodics
Pharmacology
Colicon 10 mg is an antispasmodic and anticholinergic (antimuscarinic) agent.
Absorption
Dicycloverine relieves smooth muscle spasm of the gastrointestinal tract, urinary bladder & ureter.
Distribution
As antispasmodic drug Dicycloverine causes the gut muscle to relax, relieving the pain of colic produced by gut muscle contraction and spasm.
Metabolism
Also it has direct musculotropic action.
Excretion
Dicycloverine relieves smooth muscle spasm of the gastrointestinal tract, urinary bladder & ureter.
Dosage & Administration of Colicon 10 mg
Adult
Dosage:10-20 mg three times dailyChildren (2-12 years): 10 mg three times dailyInfant (6 months-2 years): 5-10 mg (1/2-1 teaspoonful syrup) three times daily, 15 minutes before feeds
Infant (under 6 months)
Dosage:Dicycloverine should not be used under 6 month of age
| Condition | Dosage | Notes |
|---|---|---|
| Adult | 10-20 mg three times dailyChildren (2-12 years): 10 mg three times dailyInfant (6 months-2 years): 5-10 mg (1/2-1 teaspoonful syrup) three times daily, 15 minutes before feeds | |
| Infant (under 6 months) | Dicycloverine should not be used under 6 month of age |
Dosage of Colicon 10 mg
For oral dosage forms
Dosage:Adults:10 to 20 mg three times a day
Children over 6 months of age
Dosage:5 to 10 mg three times a day
For injectable dosage form
Dosage:Adults: Intramuscular injection
Notes:Not for intravenous use. The recommended intramuscular dose is 80 mg daily (in 4 equally divided doses). Oral dicycloverine Hydrochloride should be started as soon as possible and the intramuscular form should not be used for periods longer than 1 or 2 days
Children
Dosage:Dose must be determined by the doctor
| Condition | Dosage | Notes |
|---|---|---|
| For oral dosage forms | Adults:10 to 20 mg three times a day | |
| Children over 6 months of age | 5 to 10 mg three times a day | |
| For injectable dosage form | Adults: Intramuscular injection | Not for intravenous use. The recommended intramuscular dose is 80 mg daily (in 4 equally divided doses). Oral dicycloverine Hydrochloride should be started as soon as possible and the intramuscular form should not be used for periods longer than 1 or 2 days |
| Children | Dose must be determined by the doctor |
Interaction of Colicon 10 mg
The following agents may increase certain actions or side effects of anticholinergic drugs: amantadine, antiarrythmic agent of class 1 (e.g. quinidine), antihistamines, antipsychotic agents (e.g. phenothiazines), MAO inhibitors, narcotic analgesics (e.g. meperidine), nitrates and nitrites, sympathomimetic agents, tricyclic antidepressants, and other drugs having anticholinergic activity. Dicycloverine may affect the gastrointestinal absorption of various drugs, such as digoxin, metoclopramide.
Contraindications
Dicycloverine is contraindicated in:
Obstructive uropathy
Obstructive disease of the gastrointestinal tract
Severe ulcerative colitis
Reflux esophagitis
Unstable cardiovascular status in acute hemorrhage
Glaucoma
Myasthenia gravis
Evidence of prior hypersensitivity to Colicon 10 mg or other ingredients of this formulation
Infants less than 6 months of age
Side Effects of Colicon 10 mg
Insomnia, mydriasis, cycloplegia, increased ocular tension, urinary hesitancy, palpitations, dyspnea.
Pregnancy & Lactation
Dicycloverine should be used during pregnancy only if clearly needed. No teratogenic effect was shown in animal study. Since Dicycloverine hydrochloride has been reported to be secreted in human milk. So, Dicycloverine is contraindicated in lactating mother.
Precautions & Warnings
Use with caution in patients with autonomic neuropathy, hepatic or renal disease, ulcerative colitis, coronary heart disease, congestive heart failure, cardiac tachyarrhythmia, hiatal hernia, known or suspected prostatic hypertrophy.
Overdose Effects of Colicon 10 mg
Toxic reaction seldom occurs with dicycloverine. The signs and symptoms of overdosage are headache; nausea; vomiting; blurred vision; dilated pupils; hot, dry skin; dizziness; dryness of the mouth; difficulty in swallowing; and CNS stimulation.
Storage Conditions
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.
Drug Classes
Anticholinergics (antimuscarinics)/ Anti-spasmodics
Mode Of Action
Dicycloverine hydrochloride is an antispasmodic and anticholinergic (antimuscarinic) agent. Chemically, it is [Bicyclohexyl-]1-carboxylic acid, 2-(diethylammo) ethyl ester, hydrochloride. Dicycloverine relieves smooth muscle spasm of the gastrointestinal tract. Dicycloverine HCl Injection is a sterile, pyrogen-free, aqueous solution for intramuscular injection (Not For Intravenous Use). It works at specific receptors, called cholinergic (or muscarinic) receptors, located on the involuntary muscle in the walls of the gut. By binding to these receptors dicycloverine prevents certain chemicals produced by the body from interacting with these receptors. This causes the gut muscle to relax, relieving the pain of colic produced by gut muscle contraction and spasm.
Pregnancy
Pregnancy Category B. Dicycloverine was neither teratogenic nor embryocidal in animal trial. It, like other drugs should be used during pregnancy only if clearly needed. There are no data on the secretion of this drug into breast milk. Dicycloverine should be used cautiously in case of lactating mother.
Frequently Asked Questions
What is Colicon 10 mg used for?
Dicycloverine is indicated in: Functional bowel/irritable bowel syndrome Urinary incontinence secondary to unstable detrusor muscle Infantile colic GIT spasm Colicky abdominal pain Diverticulitis Abdominal colic
What is the dosage of Colicon 10 mg?
For oral dosage forms: Adults:10 to 20 mg three times a day. Children over 6 months of age: 5 to 10 mg three times a day. For injectable dosage form: Adults: Intramuscular injection. Not for intravenous use. The recommended intramuscular dose is 80 mg daily (in 4 equally divided doses). Oral dicycloverine Hydrochloride should be started as soon as possible and the intramuscular form should not be …
What are the side effects of Colicon 10 mg?
Insomnia, mydriasis, cycloplegia, increased ocular tension, urinary hesitancy, palpitations, dyspnea.
Who should not take Colicon 10 mg?
Dicycloverine is contraindicated in: Obstructive uropathy Obstructive disease of the gastrointestinal tract Severe ulcerative colitis Reflux esophagitis Unstable cardiovascular status in acute hemorrhage Glaucoma Myasthenia gravis Evidence of prior hypersensitivity to dicycloverine hydrochloride or other ingredients of this formulation Infants less than 6 months of age
What precautions should be taken with Colicon 10 mg?
Use with caution in patients with autonomic neuropathy, hepatic or renal disease, ulcerative colitis, coronary heart disease, congestive heart failure, cardiac tachyarrhythmia, hiatal hernia, known or suspected prostatic hypertrophy.
Is Colicon 10 mg safe during pregnancy and breastfeeding?
Dicycloverine should be used during pregnancy only if clearly needed. No teratogenic effect was shown in animal study. Since Dicycloverine hydrochloride has been reported to be secreted in human milk. So, Dicycloverine is contraindicated in lactating mother.
Disclaimer
The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.