10% Off
Amdocal Plus5 mg+50 mg
Amlodipine + Atenolol
Beximco Pharmaceuticals Ltd.
৳76.50
Add to cart
CVnor-A5 mg+50 mg
Amlodipine + Atenolol
Navana Pharmaceuticals Ltd.
Product Code : 4272
10% Off
Best PriceTk
/
1
Alternatives
See All
10% Off
Tenocab5 mg+50 mg
Amlodipine + Atenolol
ACI Limited
৳5.85
Add to cart
10% Off
Amloten5 mg+50 mg
Amlodipine + Atenolol
ACME Laboratories Ltd.
৳63.00
Add to cart
10% Off
Camlodin Plus5 mg+50 mg
Amlodipine + Atenolol
Square Pharmaceuticals Ltd.
৳100.80
Add to cart
10% Off
Cardipin Plus5 mg+50 mg
Amlodipine + Atenolol
Renata Limited
৳54.00
Add to cart
10% Off
Calchek Plus5 mg+50 mg
Amlodipine + Atenolol
General Pharmaceuticals Ltd.
৳6.30
Add to cart
10% Off
Lodicard5 mg+50 mg
Amlodipine + Atenolol
Aristopharma Ltd.
৳72.00
Add to cart
10% Off
Amlocard Plus5 mg+50 mg
Amlodipine + Atenolol
Drug International Ltd.
৳75.60
Add to cart
10% Off
Betacal5 mg+50 mg
Amlodipine + Atenolol
Orion Pharma Ltd.
৳5.42
Add to cart
10% Off
Bpnol Plus5 mg+50 mg
Amlodipine + Atenolol
Delta Pharma Ltd.
৳3.60
Out Of Stock
10% Off
Amlovas AT5 mg+50 mg
Amlodipine + Atenolol
Popular Pharmaceuticals Ltd.
৳54.00
Add to cart
10% Off
Combicard5 mg+50 mg
Amlodipine + Atenolol
Healthcare Pharmacuticals Ltd.
৳63.00
Add to cart
10% Off
Amocal-AT5 mg+50 mg
Amlodipine + Atenolol
Opsonin Pharma Ltd.
৳5.42
Add to cart
10% Off
Locard Plus5 mg+50 mg
Amlodipine + Atenolol
Jayson Pharma Ltd.
৳2.72
Out Of Stock
8% Off
Amlobet5 mg+50 mg
Amlodipine + Atenolol
Sun Pharmaceutical Ltd.
৳5.54
Add to cart
10% Off
Ampil Plus5 mg+50 mg
Amlodipine + Atenolol
The White Horse Pharma
৳5.40
Out Of Stock
8% Off
Betanol-A5 mg+50 mg
Amlodipine + Atenolol
Synovia Pharma PLC
৳5.54
Add to cart
10% Off
Calbeta5 mg+50 mg
Amlodipine + Atenolol
Unimed Unihealth MFG. Ltd.
৳5.40
Add to cart
10% Off
Calpin Plus5 mg+50 mg
Amlodipine + Atenolol
Globe Pharmaceuticals Ltd.
৳5.40
Add to cart
10% Off
Cardosia Plus5 mg+50 mg
Amlodipine + Atenolol
Pharmasia Limited
৳49.50
Add to cart
10% Off
Diplor Plus5 mg+50 mg
Amlodipine + Atenolol
Ibn-Sina Pharmaceuticals Ltd.
৳54.00
Add to cart
10% Off
Emlon Plus5 mg+50 mg
Amlodipine + Atenolol
Biopharma Laboratories Ltd.
৳5.42
Add to cart
10% Off
Hipre Plus5 mg+50 mg
Amlodipine + Atenolol
Pacific Pharmaceuticals Ltd.
৳5.40
Add to cart
10% Off
Sidoplus5 mg+50 mg
Amlodipine + Atenolol
Eskayef Bangladesh Ltd.
৳72.00
Add to cart
Medicine overview
Indications of CVnor-A 5 mg+50 mg
Amlodipine & Atenolol is indicated in:
Hypertension not controlled by monotherapy
Angina pectoris & hypertension co-existing diseases
Post MI patients
Refractory angina pectoris where nitrate therapy has failed
Theropeutic Class
Combined antihypertensive preparations
Pharmacology
Amlodipine is a dihydropyridine calcium antagonist that inhibits the transmembrane influx of calcium ions into vascular smooth muscle and cardiac muscle; it has a greater effect on vascular muscle than on cardiac muscle. Amlodipine is a peripheral vasodilator that acts directly on vascular smooth muscle to cause a reduction in peripheral vascular resistance and reduction in blood pressure. Amlodipine reduces tone, decreases coronary vasoreactivity and lowers cardiac demand by reducing afterload. Atenolol is a cardio selective beta blocker. The cardio selectivity is dose related. Atenolol causes a reduction in blood pressure by lowering cardiac output, decreasing the plasma renin activity and sympathetic outflow from CNS. Atenolol also causes a reduction in myocardial oxygen demand by virtue of its negative inotropic and negative chronotropic effects.
Dosage & Administration of CVnor-A 5 mg+50 mg
The recommended dosage is one tablet daily of (Amlodipine 5 mg & Atenolol 50 mg) or (Amlodipine 5 mg & Atenolol 25 mg). Depending upon the therapeutic response, titration of the dosage is recommended. In elderly patients, it is advisable to initiate the therapy with ½ tablet of fixed dose combination of Amlodipine & Atenolol (i.e. 2.5 mg of Amlodipine & 25 mg Atenolol).
Interaction of CVnor-A 5 mg+50 mg
Amlodipine has been safely administered with thiazide diuretics, beta blockers, alpha blockers, angiotensin converting enzyme inhibitors, long-acting nitrates, sublingual glyceryl trinitrate, non-steroidal anti-inflammatory agents, antibiotics, and oral hypoglycemic agents. In vitro data from studies with human plasma indicate that amlodipine has no effect on protein binding of the drugs tested (Digoxin, Phenytoin, Warfarin, or Indomethacin). Atenolol reduces the clearance of Disopyramide by 20%. Additive negative inotropic effects on the heart may be produced. At doses of 1 gm and above, Ampicillin may reduce Atenolol levels. Beta-blockers may decrease tissue sensitivity to Insulin and inhibit Insulin secretion, e.g. in response to oral antidiabetics. Atenolol has less potential for these actions.
Contraindications
Hypersensitivity to either component, sinus bradycardia, second and higher degrees of heart block, cardiogenic shock, hypotension, congestive heart failure, poor left ventricular function.
Side Effects of CVnor-A 5 mg+50 mg
The combination of Amlodipine and Atenolol is well tolerated. Overall side effects include fatigue, headache, edema, nausea, drowsiness, anxiety and depression.
Pregnancy & Lactation
Atenolol crosses the placenta. So it is contraindicated in pregnancy. It should be avoided during lactation.
Precautions & Warnings
Atenolol may mask the symptoms of hyperthyroidism. It may also mask the symptoms of hypoglycaemia, as well as enhance the effects of hypoglycaemic agents in patients with diabetes mellitus.
Storage Conditions
Store in a cool dry place protected from light. Keep out of reach of children.
Disclaimer
The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.