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Delentin

Delentin125 mg

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Medicine overview

Indications of Delentin 125 mg

This medication is used to treat intestinal worm infections such as pinwormroundworm

Theropeutic Class

Anthelmintic

Pharmacology

Pyrantel pamoate acts as a depolarizing neuromuscular blocking agent, thereby causing sudden contraction, followed by paralysis, of the helminths.

Absorption

This has the result of causing the worm to "lose its grip" on the intestinal wall and be passed out of the system by natural process. Since Pyrantel is poorly absorbed by the host's intestine, the host is unaffected by the small dosage of medication used. Spastic (tetanic) paralyzing agents, in particular Delentin 125 mg, may induce complete intestinal obstruction in a heavy worm load.

Distribution

Worms usually pass in normal stool or with diarrhea, straining, and occasional vomiting.

Dosage & Administration of Delentin 125 mg

Delentin 125 mg is given orally at anytime without regard to ingestion of food or beverages. A single dose of 11 mg/kg body weight, to a maximum of 1 gm, should be given to treat infestations caused by the parasites mentioned above. In the case of Pinworm, it is often wise to repeat the dose after an interval of 2 weeks.

Contraindications

Known hypersensitivity to pyrantel or any ingredient in the formulation.

Side Effects of Delentin 125 mg

Delentin 125 mg is well tolerated in recommended dosage. When given in large dosage, Delentin 125 mg may cause gastrointestinal upset such as anorexia, nausea, vomiting and diarrhoea. Other side effects that may occur in rare occasions are headache, dizziness and rash.

Pregnancy & Lactation

Pregnancy: Since Delentin 125 mg has not been studied in pregnant women, use of Delentin 125 mg in such patients is normally contraindicated. Delentin 125 mg is not recommended for children below 1 year of age.

Precautions & Warnings

Since Delentin 125 mg and Piperazine appear to be mutually antagonistic, Delentin 125 mg should not be given together with Piperazine. Delentin 125 mg should be kept out of the reach of children.

Use In Special Populations

Pediatric Use: Safety and efficacy not established in children <2 years of age;a use in this age group only when potential benefits justify possible risks.Hepatic Impairment: Use with caution in patients with preexisting liver dysfunction.

Frequently Asked Questions

What is Delentin 125 mg used for?

This medication is used to treat intestinal worm infections such as pinworm, roundworm, and hookworm. Pyrantel belongs to a class of drugs known as anthelmintics. It works by making the worms unable to move (paralyzed) so that the body can remove them naturally in the stool.... Read more

What is the dosage of Delentin 125 mg?

Pyrantel Pamoate is given orally at anytime without regard to ingestion of food or beverages. A single dose of 11 mg/kg body weight, to a maximum of 1 gm, should be given to treat infestations caused by the parasites mentioned above. In the case of Pinworm, it is often wise to repeat the dose after an interval of 2 weeks.

What are the side effects of Delentin 125 mg?

Pyrantel Pamoate is well tolerated in recommended dosage. When given in large dosage, Pyrantel Pamoate may cause gastrointestinal upset such as anorexia, nausea, vomiting and diarrhoea. Other side effects that may occur in rare occasions are headache, dizziness and rash.

Who should not take Delentin 125 mg?

Known hypersensitivity to pyrantel or any ingredient in the formulation.

What precautions should be taken with Delentin 125 mg?

Since Pyrantel Pamoate and Piperazine appear to be mutually antagonistic, Pyrantel Pamoate should not be given together with Piperazine. Pyrantel Pamoate should be kept out of the reach of children.

Is Delentin 125 mg safe during pregnancy and breastfeeding?

Pregnancy: Since Pyrantel Pamoate has not been studied in pregnant women, use of Pyrantel Pamoate in such patients is normally contraindicated. Pyrantel Pamoate is not recommended for children below 1 year of age.

Disclaimer

The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.

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