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Dexamin0.1%
Eye/Ear Drop
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Medicine overview
Indications of Dexamin 0.1%
cornea and anterior segment of the eye such as: anterior uveitisiritiscyclitisallergic and vernal conjunctivitisherpes zoster keratitissuch as allergic otitis externaselected purulent and non-purulent infective otitis externa.
Theropeutic Class
Aural steroid & antibiotic combined preparations, Ophthalmic Non-Steroid drugs, Ophthalmic Steroid preparations
Pharmacology
Dexamethasone is a synthetic glucocorticoid which decreases inflammation by inhibiting the migration of leukocytes and reversal of increased capillary permeability.
Absorption
It suppresses normal immune response.
Dosage & Administration of Dexamin 0.1%
Eye
Dosage:As 0.1% drop: The frequency of instillation of drops and the duration of treatment will vary depending upon the severity of the underlying condition and the response to treatment
Notes:Severe inflammations require one to two drops instilled into the eye every thirty to sixty minutes until a satisfactory response occurs. Subconjunctival or systemic steroid therapy should be considered if there is no response. When a favourable response has been observed reduce the dosage towards one drop every four hours
As 0.05% ointment
Dosage:Apply 0.5-1 inch ribbon of ointment into the conjunctival sac(s) up to 4 times daily
Notes:Reduce to once daily dosing once conditon has improved
Ear
Dosage:Instill two or three drops to the ear at two or three hour interval
Notes:The frequency of dosage and duration of the treatment may vary with the type of lesion and severity
| Condition | Dosage | Notes |
|---|---|---|
| Eye | As 0.1% drop: The frequency of instillation of drops and the duration of treatment will vary depending upon the severity of the underlying condition and the response to treatment | Severe inflammations require one to two drops instilled into the eye every thirty to sixty minutes until a satisfactory response occurs. Subconjunctival or systemic steroid therapy should be considered if there is no response. When a favourable response has been observed reduce the dosage towards one drop every four hours |
| As 0.05% ointment | Apply 0.5-1 inch ribbon of ointment into the conjunctival sac(s) up to 4 times daily | Reduce to once daily dosing once conditon has improved |
| Ear | Instill two or three drops to the ear at two or three hour interval | The frequency of dosage and duration of the treatment may vary with the type of lesion and severity |
Interaction of Dexamin 0.1%
None relevant to topical use.
Contraindications
Epithelial herpes simplex keratitis (dendritic keratitis), acute infections stages of vaccinia, varicella, and many other viral diseases of the cornea and conjunctiva, Mycobacterial infection of the eye, Fungal diseases of ocular or auricular structures, perforation of a drum membrane. Hypersensitivity to any ingredient of this product.
Side Effects of Dexamin 0.1%
Glaucoma with optic nerve damage, visual acuity and field defects, posterior subcapsular cataract formation, secondary ocular infection from pathogens including herpes simplex, perforation of the globe. Rarely, stinging and burning may occur.
Pregnancy & Lactation
Pregnancy category C. There is no adequate and well-controlled studies in pregnant women. This drug should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Lactation: Caution should be exercised when Dexamethasone ophthalmic solution is administered to a nursing woman.
Precautions & Warnings
The possibility of persistent fungal infections of the cornea should be considered after prolonged corticosteroid dosing. There have been reports of bacterial keratitis associated with the use of multiple dose containers of topical ophthalmic products. These containers had been inadvertently contaminated by patients who, in most cases, had a concurrent corneal disease or a disruption of the ocular epithelial surface.
Overdose Effects of Dexamin 0.1%
Long-term intensive topical use may lead to systemic effects. Oral ingestion of the contents of the bottle (up to 10 ml) is unlikely to lead to any serious adverse effects.
Storage Conditions
Store below 30° C in a cool and dry place protected from light. Keep out of reach of children. Do not touch the dropper tip to surfaces since this may contaminate the solution. Do not use after 30 days of first opening.
Use In Special Populations
Pediatric Use: Safety and efficacy in pediatric patients below the age of 18 have not been established.
Frequently Asked Questions
What is Dexamin 0.1% used for?
Eye: Dexamethasone Phosphate is indicated for treatment of steroid responsive inflammatory conditions of the conjunctiva, cornea and anterior segment of the eye such as: anterior uveitis, iritis, cyclitis, allergic and vernal conjunctivitis, herpes zoster keratitis, superficial punctate keratitis and non-specific superficial keratitis. Also indicated for the treatment of corneal injury from chemic…
What is the dosage of Dexamin 0.1%?
Eye: As 0.1% drop: The frequency of instillation of drops and the duration of treatment will vary depending upon the severity of the underlying condition and the response to treatment. Severe inflammations require one to two drops instilled into the eye every thirty to sixty minutes until a satisfactory response occurs. Subconjunctival or systemic steroid therapy should be considered if there is n…
What are the side effects of Dexamin 0.1%?
Glaucoma with optic nerve damage, visual acuity and field defects, posterior subcapsular cataract formation, secondary ocular infection from pathogens including herpes simplex, perforation of the globe. Rarely, stinging and burning may occur.
Who should not take Dexamin 0.1%?
Epithelial herpes simplex keratitis (dendritic keratitis), acute infections stages of vaccinia, varicella, and many other viral diseases of the cornea and conjunctiva, Mycobacterial infection of the eye, Fungal diseases of ocular or auricular structures, perforation of a drum membrane. Hypersensitivity to any ingredient of this product.
What precautions should be taken with Dexamin 0.1%?
The possibility of persistent fungal infections of the cornea should be considered after prolonged corticosteroid dosing. There have been reports of bacterial keratitis associated with the use of multiple dose containers of topical ophthalmic products. These containers had been inadvertently contaminated by patients who, in most cases, had a concurrent corneal disease or a disruption of the ocular…
Is Dexamin 0.1% safe during pregnancy and breastfeeding?
Pregnancy category C. There is no adequate and well-controlled studies in pregnant women. This drug should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. Lactation: Caution should be exercised when Dexamethasone ophthalmic solution is administered to a nursing woman.
Disclaimer
The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.