Diconten

Diconten0.5 mg+10 mg

Tablet

Flupentixol + Melitracen

Drug International Ltd.

Product Code : 4967
MRP 70.00
10% Off
Best PriceTk
/
1
Section

Alternatives

See All
Product Image
10% Off

Angenta0.5 mg+10

Flupentixol + Melitracen

Healthcare Pharmacuticals Ltd.

4.50
5.00
Add to cart
Product Image
10% Off

Frenxit0.5 mg+10

Flupentixol + Melitracen

Beximco Pharmaceuticals Ltd.

4.50
5.00
Add to cart
Product Image
10% Off

Fluxit0.5 mg+10

Flupentixol + Melitracen

Opsonin Pharma Ltd.

45.18
50.20
Add to cart
Product Image
10% Off

Anfree0.5 mg+10

Flupentixol + Melitracen

Aristopharma Ltd.

4.50
5.00
Add to cart
Product Image
10% Off

Melixol0.5 mg+10

Flupentixol + Melitracen

Square Pharmaceuticals Ltd.

4.52
5.02
Add to cart
Product Image
10% Off

Stimo0.5 mg+10

Flupentixol + Melitracen

Delta Pharma Ltd.

3.15
3.50
Add to cart
Product Image
10% Off

Deleta0.5 mg+10

Flupentixol + Melitracen

General Pharmaceuticals Ltd.

45.00
50.00
Add to cart
Product Image
10% Off

Adelax0.5 mg+10

Flupentixol + Melitracen

ACI Limited

45.18
50.20
Add to cart
Product Image
10% Off

Renxit0.5 mg+10

Flupentixol + Melitracen

Renata Limited

4.50
5.00
Add to cart
Product Image
10% Off

Tenaxit0.5 mg+10

Flupentixol + Melitracen

Incepta Pharmaceuticals Ltd.

4.50
5.00
Add to cart
Product Image
10% Off

Anzet0.5 mg+10

Flupentixol + Melitracen

Popular Pharmaceuticals Ltd.

45.00
50.00
Add to cart
Product Image
10% Off

Sensit0.5 mg+10

Flupentixol + Melitracen

Eskayef Bangladesh Ltd.

4.50
5.00
Add to cart
Product Image
10% Off

Remood0.5 mg+10

Flupentixol + Melitracen

Ibn-Sina Pharmaceuticals Ltd.

4.50
5.00
Add to cart
Product Image
10% Off

Dexit0.5 mg+10

Flupentixol + Melitracen

Unimed Unihealth MFG. Ltd.

4.50
5.00
Add to cart
Product Image
10% Off

Leanxit0.5 mg+10

Flupentixol + Melitracen

ACME Laboratories Ltd.

4.51
5.01
Add to cart
Product Image
10% Off

U40.5 mg+10

Flupentixol + Melitracen

Orion Pharma Ltd.

4.51
5.01
Add to cart
Product Image
10% Off

Radex0.5 mg+10

Flupentixol + Melitracen

Globe Pharmaceuticals Ltd.

45.00
50.00
Add to cart
Product Image
10% Off

Benzit0.5 mg+10

Flupentixol + Melitracen

Biopharma Laboratories Ltd.

4.50
5.00
Add to cart
Product Image
10% Off

Eraxit0.5 mg+10

Flupentixol + Melitracen

Pharmasia Limited

45.00
50.00
Add to cart
Product Image
10% Off

Thixtra0.5 mg+10

Flupentixol + Melitracen

NIPRO JMI Pharma Ltd.

4.52
5.02
Add to cart
Product Image
10% Off

Meltix0.5 mg+10

Flupentixol + Melitracen

Navana Pharmaceuticals Ltd.

4.50
5.00
Add to cart
Product Image
10% Off

Xolitra0.5 mg+10

Flupentixol + Melitracen

Beacon Pharmaceuticals Ltd.

4.52
5.02
Add to cart
Product Image
10% Off

Thenxet0.5 mg+10

Flupentixol + Melitracen

Pacific Pharmaceuticals Ltd.

4.50
5.00
Add to cart
Product Image
8% Off

Exzilor0.5 mg+10

Flupentixol + Melitracen

Sun Pharmaceutical Ltd.

3.70
4.02
Add to cart
Product Image
10% Off

FMR0.5 mg+10

Flupentixol + Melitracen

Julphar Bangladesh Ltd.

4.50
5.00
Add to cart
Product Image
10% Off

Melxit0.5 mg+10

Flupentixol + Melitracen

Ziska Pharmaceuticals Ltd.

4.50
5.00
Add to cart
Product Image
10% Off

Tensicon0.5 mg+10

Flupentixol + Melitracen

The White Horse Pharma

4.50
5.00
Out Of Stock
Section

Medicine overview

Indications of Diconten 0.5 mg+10 mg

Diconten 0.5 mg+10 mg tablet is indicated in- Anxiety Depression Apathy Psychogenic depression. Depressive neurosses. Masked depression. Psychosomatic affections accompanied by anxiety and apathy. Menopausal depressions. Dysphoria and depression in alcoholics and drug addicts.

Theropeutic Class

Combined anxiolytics & anti-depressant drugs

Pharmacology

Maximum serum concentration is reached in about 4 hours after oral administration of Diconten 0.5 mg+10 mg. The half-life of Flupentixol is about 35 hours and that of Melitracen is about 19 hours. The combination of Flupentixol and Melitracen does not seem to influence the pharmacokinetic properties of the individual compounds. Flupenthixol primarily acts as a neuroleptic drug. The antipsychotic effect of Flupenthixol is achieved by mixed blockade of dopamine D1 and D2 receptors. In the mesolimbic dopamine system of the brain, this accounts for the antipsychotic action of this drug. Flupenthixol has other effects on CNS. In the chemoreceptor trigger zone, the dopamine blockade accounts for the antiemetic effect of the drug.Melitracen is a tricyclic antidepressant. It blocks the neuronal re-uptake of both serotonin and nor-epinephrine in the central nervous system, there by minimizing the symptoms of depression.

Dosage & Administration of Diconten 0.5 mg+10 mg

Adults: Usually 2 tablets daily, in morning and afternoon. In severe cases, the morning dose may be increased to 2 tablets.Elderly patients: 1 tablet in the morning. Maintenance dose: Usually 1 tablet in the morning or as directed by the physician.

Dosage of Diconten 0.5 mg+10 mg

Adults: Usually 2 tablets orally daily in the morning and noon. In severe cases, the morning dose may be increased to 2 tablets.Elderly patients: 1 tablet in the morning. Maintenance dose: Usually 1 tablet orally in the morning. In cases of insomnia or severe restlessness, additional treatment with a sedative in the acute phase is recommended.

Interaction of Diconten 0.5 mg+10 mg

This tablet may enhance the response to alcohol, barbiturates and other CNS depressants. Simultaneous administration of MAO-inhibitors may cause hypertensive crises. Neuroleptics and thymoleptics reduce the antihypertensive effect of guanethidine and similar acting compounds and thymoleptics enhance the effects of adrenaline and noradrenaline.

Contraindications

The immediate recovery phase after myocardial infarction. Defects in bundle-branch conduction. Untreated narrow-angle glaucoma. Acute alcohol, barbiturate and opiate intoxications. This tablet should not be given to patients who have received an MAO-inhibitor within two weeks. Not recommended for excitable or overactive patients since its activating effect may lead to exaggeration of these characteristics.

Side Effects of Diconten 0.5 mg+10 mg

In the recommended doses side effects are rare. These could be transient restlessness and insomnia.

Pregnancy & Lactation

The safety of this drug has not been established in pregnancy and lactation.

Precautions & Warnings

If previously the patient has been treated with tranquillizers with sedative effect these should be withdrawn gradually.

Overdose Effects of Diconten 0.5 mg+10 mg

In cases of overdosage the symptoms of intoxications by melitracen, especially of anticholinergic nature, dominate. More rarely extrapyramidal symptoms due to flupentixol occur. Symptomatic and Supportive. Gastric lavage should be carried out as soon as possible and activated charcoal may be administered. Measures aimed at supporting the respiratory and cardiovascular systems should be instituted. Epinephrine (adrenaline) must not be used for such patients. Convulsions may be treated with diazepam and extrapyramidal symptoms with biperiden.

Storage Conditions

Store at a temperature not exceeding 30°C in a dry place. Protect from light. Keep out of reach of children.

Drug Classes

Combined anxiolytics & anti-depressant drugs

Mode Of Action

This consists of two well known and well proven compounds: flupentixol-a neuroleptic with anxiolytic and antidepressant properties of its own when given in small doses, and melitracen-a bipolar thymoleptic with activating properties in low doses. In combination the compounds render a preparation with antidepressant, anxiolytic and activating properties. Maximal serum concentration is reached in about 4 hours after oral administration of flupentixol and in about 4 hours after oral administration of melitracen. The biological half-life of flupentixol is about 35 hours and that of melitracen is about 19 hours. The combination of Diconten 0.5 mg+10 mg does not seem to influence the pharmacokinetic properties of the individual compounds.

Pregnancy

This tablet should preferably not be given during pregnancy and lactation.

Disclaimer

The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.