Dilate Plus

Dilate Plus0.8%+5%

Ophthalmic Solution

Tropicamide + Phenylephrine Hydrochloride

Incepta Pharmaceuticals Ltd.

Product Code : 4999
MRP 80.00
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Medicine overview

Indications of Dilate Plus 0.8%+5%

Therapeutic purpose: Inflammatory conditions of the uveal tract. May be used in temporary lowering of intraocular pressure in glaucoma. Diagnostic purpose: Retinal photography. Refractive errors. Fundus examination/photography. ... Read moreTherapeutic purpose: Inflammatory conditions of the uveal tract. May be used in temporary lowering of intraocular pressure in glaucoma. Diagnostic purpose: Retinal photography. Refractive errors. Fundus examination/photography. Slit lamp examination. Pre-operative use: In order to undergo surgical procedure that requires the visualization of structures behind the iris, such as cataract extraction, vitrectomy and retinal detachment surgery.

Theropeutic Class

Preparations for Ophthalmic diagnosis

Pharmacology

Tropicamide binds to and blocks the receptors in the muscles of the eye (muscarinic receptor M4). Tropicamide acts by blocking the responses of the iris sphincter muscle to the iris and ciliary muscles to cholinergic stimulation, producing dilation of the pupil and paralysis of the ciliary muscle.Phenylephrine Hydrochloride is a selective alpha-1 agonist, which causes mydriasis without cycloplegia. It tends to reduce intraocular lesion by vasoconstrictor action.

Dosage & Administration of Dilate Plus 0.8%+5%

Uveitis: 1-2 drops bid-qid or as required. Diagnostic purpose/Pre-operative purpose: Instill 1-2 drops in the eye(s) 15-20 minutes before examination. If examination is not conducted within 20–30 minutes, an additional drop may be placed in the eye(s) to prolong the effect.

Dosage of Dilate Plus 0.8%+5%

Uveitis: 1-2 drops bid-qid or as required. Diagnostic purpose/Pre-operative purpose: Instill 1-2 drops in the eye(s) 15-20 minutes before examination. If examination is not conducted within 20–30 minutes, an additional drop may be placed in the eye(s) to prolong the effect.

Interaction of Dilate Plus 0.8%+5%

Tropicamide may interfere with the antihypertensive action of carbachol, pilocarpine or ophthalmic cholinesterase inhibitors.

Contraindications

This medication is contraindicated in these following cases Patients with hypersensitivity to any of the components and narrow angles or narrow angle glaucoma. Low birth weight infants and some elderly adults with severe arteriosclerotic cardiovascular or cerebrovascular disease. During intraocular operative procedures when the corneal epithelial barrier has been disturbed.

Side Effects of Dilate Plus 0.8%+5%

Elevated IOP (occasionally), stinging, blurred vision, tachycardia, photophobia, headache, parasympathetic stimulation and allergic reactions. Systemic effects include arrhythmias, hypertension and coronary artery spasm.

Pregnancy & Lactation

The safety of this medication during pregnancy or lactation has not been established.

Precautions & Warnings

Caution should be taken when administered with, or upto 21days after administration of monoamine oxidase (MAO) inhibitors as exaggerated adrenergic effects may result.The possibility of psychotic reactions and behavioral disturbances should be considered in patients who are hypersensitive to anticholinergic drugs.Use with extreme caution in infants.

Overdose Effects of Dilate Plus 0.8%+5%

Excessive use in children and in certain susceptible individuals may produce systemic toxic symptoms.

Storage Conditions

Keep out of the reach of children. Store in a cool, dry place, away from heat and direct light. Do not use more than 4 weeks after opening. 

Drug Classes

Preparations for Ophthalmic diagnosis

Mode Of Action

Tropicamide binds to and blocks the receptors in the muscles of the eye (muscarinic receptor M4). Tropicamide acts by blocking the responses of the iris sphincter muscle to the iris and ciliary muscles to cholinergic stimulation, producing dilation of the pupil and paralysis of the ciliary muscle.Phenylephrine Hydrochloride is a selective alpha-1 agonist, which causes mydriasis without cycloplegia. It tends to reduce intraocular lesion by vasoconstrictor action.

Pregnancy

The safety of this medication during pregnancy or lactation has not been established.
Disclaimer

The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.