Disprin300 mg

Disprin 300 mg is indicated in the following indications -

Prophylaxis against arterial occlusive events: Myocardial infarction, myocardial re-infarction, after bypass surgery, acute ischemic stroke/TIA.

Mild to moderate pain: Headache, muscle pain, dysmenorrhea, and toothache, etc.

Chronic disease accompanied by pain and inflammation: Osteoarthritis.

Antipyretic: Cold fever and influenza.

Anti-platelet drugs

By decreasing platelet aggregation, Disprin 300 mg inhibits thrombus formation on the arterial side of circulation, where thrombi are formed by platelet aggregation and anticoagulants have little effect. It is the analgesic of choice for headache, transient musculoskeletal pain, and dysmenorrhea. It has anti-inflammatory and antipyretic properties, which may be useful. Enteric coating reduces the intestinal disturbance and gastrointestinal ulceration due to this medicine.

Pain, Inflammatory diseases and as Antipyretic: Disprin 300 mg 300 mg 1-3 tablets 6 hourly with a maximum daily dose of 4 g.

Thrombotic cerebrovascular or Cardiovascular disease: Disprin 300 mg 300 mg 1 tablet or Disprin 300 mg 75 mg 4 tablets daily.

After Myocardial infarction: Disprin 300 mg 75 mg 2 tablets daily for 1 month.

Following By-pass surgery: Disprin 300 mg 75 mg 1 tablet daily.

Salicylates may enhance the effect of anticoagulants, oral hypoglycemic agents, phenytoin, and sodium valproate. They inhibit the uricosuric effect of probenecid and may increase the toxicity of sulfonamides. They may also precipitate bronchospasm or induce attacks of asthma in susceptible subjects.

Disprin 300 mg is contraindicated in children under 12 years of age (due to the risk of Reye's syndrome), during breastfeeding, and in cases of active peptic ulcer. It should also be avoided in conditions involving bleeding, such as hemophilia, intracranial hemorrhage, and other ulcerations.

Side effects for the typical dosage of Disprin 300 mg are generally mild and may include nausea, dyspepsia, gastrointestinal ulceration, and bronchospasm, among others.

It should be administered cautiously in cases of asthma, uncontrolled blood pressure, and during pregnancy.It should be administered with caution to patients with nasal polyps and nasal allergies.

Overdosage can result in symptoms such as dizziness, tinnitus, sweating, nausea, vomiting, confusion, and hyperventilation. Severe overdosage may lead to central nervous system depression with coma, cardiovascular collapse, and respiratory depression.

If an overdose is suspected, it is crucial to closely monitor the patient for at least 24 hours, as symptoms and salicylate blood levels may not become evident for several hours. The treatment for overdosage involves gastric lavage and forced alkaline diuresis. In severe cases, hemodialysis may be necessary.

Keep all medicines out of reach of children. Store in a cool and dry place, protected from light.

Anti-platelet drugs

By reducing platelet aggregation, Disprin 300 mg inhibits thrombus formation on the arterial side of circulation, where thrombi primarily form through platelet aggregation, and anticoagulants have limited impact.

This medication is the preferred analgesic for addressing conditions such as headaches, transient musculoskeletal pain, and dysmenorrhea. It possesses anti-inflammatory and antipyretic properties, which can be beneficial. Enteric-coated Disprin 300 mg is effective in reducing intestinal disturbance and the risk of gastrointestinal ulceration due to its properties.

It is particularly crucial to avoid using Disprin 300 mg during the final three months of pregnancy unless explicitly instructed by a physician, as it may lead to issues in the unborn child or complications during delivery.

Disprin 300 mg can enter breast milk, so it should be administered cautiously to nursing mothers.