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Span40 mg
Drotaverine
Opsonin Pharma Ltd.
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Dot40 mg
Tablet
Drotaverine
ACME Laboratories Ltd.
Product Code : 5258
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Medicine overview
Indications of Dot 40 mg
Spastic conditions of the gastrointestinal tract, irritable bowel syndrome-
Biliary colics and spastic conditions of the biliary tract: Cholecystolithiasis, cholecystitis, cholangitis.
Renal colics and spastic conditions of the urogenital tract: Nephrolithiasis, ureterolithiasis, pyelitis, cystitis. ... Read moreSpastic conditions of the gastrointestinal tract, irritable bowel syndrome-
Biliary colics and spastic conditions of the biliary tract: Cholecystolithiasis, cholecystitis, cholangitis.
Renal colics and spastic conditions of the urogenital tract: Nephrolithiasis, ureterolithiasis, pyelitis, cystitis.
Spastic conditions of the uterus: Dysmenorrhea, imminent abortion, uterine tetanus.
Theropeutic Class
Anticholinergics
Pharmacology
Dot 40 mg has antispasmodic effect mediated via inhibition of phosphodiesterase-IV, specific for smooth muscle. It has a rapid and direct action on the smooth muscle. It acts to correct cyclic AMP and Ca imbalance at the spastic site, thereby relieving smooth muscle spasm and pain.
Dosage & Administration of Dot 40 mg
Oral-
Adults: 1 to 2 tablets, 3 times daily
Children (over 6 years): 1/2 to 1 tablet, 1-2 times daily.
Children (1-6 years): 1/4 to 1/2 tablet, 1-2 times daily.
Injection-
Adults: 1 to 2 ampoules, intramuscularly or subcutaneously, 1-3 times daily.
For the management of acute stone colics: 1 or 2 ampoules by slow intravenous injection.
Dosage of Dot 40 mg
Oral-
Adults: 1 to 2 tablets, 3 times daily
Children (over 6 years): 1/2 to 1 tablet, 1-2 times daily.
Children (1-6 years): 1/4 to 1/2 tablet, 1-2 times daily.
Injection-
Adults: 1 to 2 ampoules, intramuscularly or subcutaneously, 1-3 times daily.
For the management of acute stone colics: 1 or 2 ampoules by slow intravenous injection.
Interaction of Dot 40 mg
May attenuate the action of levodopa. Concurrent use of analgesics, antimuscarinics or benzodiazepines. Additive beneficial effect with concurrent use of analgesics, antimuscarinics or benzodiazepines.
Contraindications
Dot 40 mg is contraindicated in patients with known hypersensitivity to the products and its constituents.
Side Effects of Dot 40 mg
The common side effects are headache, dizziness, rhinitis, sinusitis, gastrointestinal upset, nausea, pharyngitis, edema and fatigue.
Pregnancy & Lactation
As with most drugs, the use of Dot 40 mg Hydrochloride should be avoided during pregnancy and lactation unless essential.
Precautions & Warnings
Caution should be taken for patients suffering from liver and kidney disease.
Drug Classes
Anticholinergics
Mode Of Action
Dot 40 mg has antispasmodic effect mediated via inhibition of phosphodiesterase-IV, specific for smooth muscle. It has a rapid and direct action on the smooth muscle. It acts to correct cyclic AMP and Ca imbalance at the spastic site, thereby relieving smooth muscle spasm and pain.
Pregnancy
As with most drugs, the use of Dot 40 mg Hydrochloride should be avoided during pregnancy and lactation unless essential.
Disclaimer
The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.
