Elorim

Elorim13.9%

Cream

Eflornithine Hydrochloride

Square Pharmaceuticals Ltd.

Product Code : 5661
MRP 1500.00
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Medicine overview

Indications of Elorim 13.9%

Elorim 13.9% cream, 13.9% is indicated for the reduction of unwanted facial hair in women. Elorim 13.9% has only been studied on the face and adjacent involved areas under the chin of affected individuals. Usage should be limited to these areas of involvement.

Theropeutic Class

Hair Growth Inhibitor

Pharmacology

Eflornithine prevents hair growth by inhibiting the anagen phase of hair production. This occurs by eflornithine irreversibly binding (also called suicide inhibition) to ornithine decarboxylase (ODC) and physically preventing the natural substrate ornithine from accessing the active site.

Dosage & Administration of Elorim 13.9%

Adults: Apply a thin layer of Eflornithine cream, 13.9% to affected areas of the face and adjacent involved areas under the chin and rub in thoroughly. Do not wash treated area for at least 4 hours. Use twice daily at least 8 hours apart or as directed by a physician. The patient should continue to use hair removal techniques as needed in conjunction with Eflornithine (Wonica should be applied at least 5 minutes after hair removal). Cosmetics or sunscreens may be applied over treated areas after cream has dried. Elderly: No apparent differences in safety were observed between older patients and younger patients. Children: The safety and effectiveness of this product have not been established in pediatric patients less than 12 years of age.

Dosage of Elorim 13.9%

Adults: Apply a thin layer of Eflornithine cream, 13.9% to affected areas of the face and adjacent involved areas under the chin and rub in thoroughly. Do not wash treated area for at least 4 hours. Use twice daily at least 8 hours apart or as directed by a physician. The patient should continue to use hair removal techniques as needed in conjunction with Eflornithine (Wonica should be applied at least 5 minutes after hair removal). Cosmetics or sunscreens may be applied over treated areas after cream has dried. Elderly: No apparent differences in safety were observed between older patients and younger patients. Children: The safety and effectiveness of this product have not been established in pediatric patients less than 12 years of age.

Interaction of Elorim 13.9%

It is not known whether Eflornithine has any interaction with other topically applied drug products.

Contraindications

Eflornithine is contraindicated in patients with a history of sensitivity to any components of the preparation.

Side Effects of Elorim 13.9%

Adverse events were primarily mild in intensity and generally resolved without medical treatment or discontinuation of Eflornithine. Side effects can include acne, barbae, pseudofolliculitis, stinging skin, headache, burning skin, dry skin, erythema (redness), pruritus (itching), tingling skin, dyspepsia, skin irritation, rash, alopecia, dizziness, folliculitis, hair ingrown, facial edema, anorexia, nausea, asthenia, vertigo

Pregnancy & Lactation

Pregnancy Category C. It is not known whether or not Elorim 13.9% is excreted in human milk. Caution should be exercised when Eflornithine is administered to a nursing woman.

Precautions & Warnings

For external use only. Transient stinging or burning may occur when applied to abraded or broken skin.

Overdose Effects of Elorim 13.9%

Overdosage information with Eflornithine is unavailable. However, if very high topical doses (e.g., multiple tubes per day) or oral ingestion has been encountered (a 30 gm tube contains 4.2 gm of Elorim 13.9%), the patient should be monitored, and appropriate supportive measures should be administered as necessary.

Storage Conditions

Store at 25°C, excursions permitted to 15°C-30°C. Do not freeze.

Drug Classes

Hair Growth Inhibitor

Mode Of Action

Eflornithine prevents hair growth by inhibiting the anagen phase of hair production. This occurs by eflornithine irreversibly binding (also called suicide inhibition) to ornithine decarboxylase (ODC) and physically preventing the natural substrate ornithine from accessing the active site.

Pregnancy

Pregnancy Category C. It is not known whether or not Elorim 13.9% is excreted in human milk. Caution should be exercised when Eflornithine is administered to a nursing woman.
Disclaimer

The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.