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Emezin50 mg
Tablet
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Medicine overview
Indications of Emezin 50 mg
Emezin 50 mg is indicated in nauseavomitingmotion sicknessvertigo.
Theropeutic Class
Anti-emetic drugs
Pharmacology
Meclizine has antiemetic, anticholinergic and antihistaminic properties.
Absorption
It reduces the sensitivity of the labyrinthine apparatus.
Distribution
The action may be mediated through nerve pathways to the vomiting center (VC) from the chemoreceptor trigger zone (CTZ), peripheral nerve pathways, the VC, or other CNS centers.
Metabolism
Meclizine has an onset of action of 30 to 60 minutes, depending on dosage; their duration of action is 12 to 24 hours.
Dosage & Administration of Emezin 50 mg
Adult & children over 12 years of age
Dosage:Nausea and vomiting: 25-50 mg once daily
Motion sickness
Dosage:Take an initial dose of 25 to 50 mg, 1 hour prior to travel
Notes:May repeat dose every 24 hours for the duration of the journey
Children
Dosage:Age 6-12 years, 12.5 mg once daily
Notes:Age 2-6 years, 6.25 mg once daily
Vertigo
Dosage:25 to 100 mg daily in divided doses
Radiotherapy induced nausea and vomiting
Dosage:50 mg two to twelve hours prior to radiotherapy
Emergency contraception
Dosage:25-50 mg, 1 hour before first ECP dose; repeat if needed in 24 hours
Use in children
Dosage:Clinical studies establishing safety and efficacy in children have not been done; therefore, its use should be determined by physician
Use in elderly
Dosage:There is no specific information available
Notes:However older people may be especially sensitive to the anticholinergic effects of medicine
| Condition | Dosage | Notes |
|---|---|---|
| Adult & children over 12 years of age | Nausea and vomiting: 25-50 mg once daily | |
| Motion sickness | Take an initial dose of 25 to 50 mg, 1 hour prior to travel | May repeat dose every 24 hours for the duration of the journey |
| Children | Age 6-12 years, 12.5 mg once daily | Age 2-6 years, 6.25 mg once daily |
| Vertigo | 25 to 100 mg daily in divided doses | |
| Radiotherapy induced nausea and vomiting | 50 mg two to twelve hours prior to radiotherapy | |
| Emergency contraception | 25-50 mg, 1 hour before first ECP dose; repeat if needed in 24 hours | |
| Use in children | Clinical studies establishing safety and efficacy in children have not been done; therefore, its use should be determined by physician | |
| Use in elderly | There is no specific information available | However older people may be especially sensitive to the anticholinergic effects of medicine |
Dosage of Emezin 50 mg
Adult & children over 12 years of age
Dosage:Nausea and vomiting: 25-50 mg once daily
Motion sickness
Dosage:Take an initial dose of 25 to 50 mg, 1 hour prior to travel
Notes:May repeat dose every 24 hours for the duration of the journey
Children
Dosage:Age 6-12 years, 12.5 mg once daily
Notes:Age 2-6 years, 6.25 mg once daily
Vertigo
Dosage:25 to 100 mg daily in divided doses
Radiotherapy induced nausea and vomiting
Dosage:50 mg two to twelve hours prior to radiotherapy
Emergency contraception
Dosage:25-50 mg, 1 hour before first ECP dose; repeat if needed in 24 hours
Use in children
Dosage:Clinical studies establishing safety and efficacy in children have not been done; therefore, its use should be determined by physician
Use in elderly
Dosage:There is no specific information available
Notes:However older people may be especially sensitive to the anticholinergic effects of medicine
| Condition | Dosage | Notes |
|---|---|---|
| Adult & children over 12 years of age | Nausea and vomiting: 25-50 mg once daily | |
| Motion sickness | Take an initial dose of 25 to 50 mg, 1 hour prior to travel | May repeat dose every 24 hours for the duration of the journey |
| Children | Age 6-12 years, 12.5 mg once daily | Age 2-6 years, 6.25 mg once daily |
| Vertigo | 25 to 100 mg daily in divided doses | |
| Radiotherapy induced nausea and vomiting | 50 mg two to twelve hours prior to radiotherapy | |
| Emergency contraception | 25-50 mg, 1 hour before first ECP dose; repeat if needed in 24 hours | |
| Use in children | Clinical studies establishing safety and efficacy in children have not been done; therefore, its use should be determined by physician | |
| Use in elderly | There is no specific information available | However older people may be especially sensitive to the anticholinergic effects of medicine |
Interaction of Emezin 50 mg
Meclizine may increase the toxicity with CNS depressants, neuroleptics and anticholinergic. Alcohol, sedatives and tranquilizers can increase the drowsiness of the patient.
Contraindications
Meclizine is contraindicated in patients hypersensitive to Meclizine or any of its excipeints.
Side Effects of Emezin 50 mg
Common side effects are Drowsiness, dry mouth, and on rare occasions, blurred vision have been reported.
Pregnancy & Lactation
Meclizine shows no risk of birth defects or abnormalities when administered during pregnancy. Although Meclizine may excrete into the milk, it causes no harm in nursing babies.
Precautions & Warnings
Patients with asthma, bronchitis, emphysema, enlarged prostate, glaucoma or urinary tract blockage should take Meclizine (like other antiemetics) with caution.
Overdose Effects of Emezin 50 mg
Symptoms: Extreme excitability, seizures, drowsiness and hallucinations. Treatment: Appropriate supportive and symptomatic treatment. Consider dialysis.
Storage Conditions
Store in a cool & dry place and away from children.
Drug Classes
Anti-emetic drugs
Mode Of Action
Meclizine has antiemetic, anticholinergic and antihistaminic properties. It reduces the sensitivity of the labyrinthine apparatus. The action may be mediated through nerve pathways to the vomiting center (VC) from the chemoreceptor trigger zone (CTZ), peripheral nerve pathways, the VC, or other CNS centers. Meclizine has an onset of action of 30 to 60 minutes, depending on dosage; their duration of action is 12 to 24 hours.
Pregnancy
Meclizine shows no risk of birth defects or abnormalities when administered during pregnancy. Although Meclizine may excrete into the milk, it causes no harm in nursing babies.
Frequently Asked Questions
What is Emezin 50 mg used for?
Meclizine Hydrochloride is indicated in nausea, vomiting, motion sickness, vertigo.
What is the dosage of Emezin 50 mg?
Adult & children over 12 years of age: Nausea and vomiting: 25-50 mg once daily. Motion sickness: Take an initial dose of 25 to 50 mg, 1 hour prior to travel. May repeat dose every 24 hours for the duration of the journey. Children: Age 6-12 years, 12.5 mg once daily. Age 2-6 years, 6.25 mg once daily. Vertigo: 25 to 100 mg daily in divided doses. Radiotherapy induced nausea and vomiting: 50 mg tw…
What are the side effects of Emezin 50 mg?
Common side effects are Drowsiness, dry mouth, and on rare occasions, blurred vision have been reported.
Who should not take Emezin 50 mg?
Meclizine is contraindicated in patients hypersensitive to Meclizine or any of its excipeints.
What precautions should be taken with Emezin 50 mg?
Patients with asthma, bronchitis, emphysema, enlarged prostate, glaucoma or urinary tract blockage should take Meclizine (like other antiemetics) with caution.
Is Emezin 50 mg safe during pregnancy and breastfeeding?
Meclizine shows no risk of birth defects or abnormalities when administered during pregnancy. Although Meclizine may excrete into the milk, it causes no harm in nursing babies.
Disclaimer
The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.