Indapa-SR 1.5 mg is indicated in the treatment of essential hypertension . It is effective in treating hypertension in patients with renal function impairment, although its diuretic effect is reduced. Indapa-SR 1.5 mg is also indicated for the treatment of salt and fluid retention associated with congestive heart failure.
Theropeutic Class
Thiazide diuretics & related drugs
Pharmacology
Indapa-SR 1.5 mg is a diuretic antihypertensive. It appears to cause vasodilation, probably by inhibiting the passage of calcium and other ions (sodium, potassium) across membranes. It has an extra-renal antihypertensive action resulting in a decrease in vascular hyperreactivity and a reduction in total peripheral and arteriolar resistance.
Dosage & Administration of Indapa-SR 1.5 mg
One tablet daily preferably in the morning. In more sever case Indapa-SR 1.5 mg can be combine with other categories of anti-hypertensive agent. The safety and effectiveness in pediatric patients have not been established
Dosage of Indapa-SR 1.5 mg
One tablet daily preferably in the morning. In more sever case Indapa-SR 1.5 mg can be combine with other categories of anti-hypertensive agent. The safety and effectiveness in pediatric patients have not been established
Interaction of Indapa-SR 1.5 mg
Other antihypertensive: Indapa-SR 1.5 mg may add to or potentiate the action of other antihypertensive drugs. Norepinephrine: Indapa-SR 1.5 mg like thiazides, may decrease arterial responsiveness to norepinephrine. Lithium: In general, diuretics should not be given concomitantly with lithium because they reduce its renal clearance and add a high risk of lithium toxicity.
Contraindications
This drug must not be taken in the following conditions:
Hypersensitivity to sulfonamides
Severe renal failure
Hepatic encephalopathy or severe hepatic failure
Hypokalaemia
Side Effects of Indapa-SR 1.5 mg
Side effects of Indapa-SR 1.5 mg include headache, anorexia, gastric irritation,nausea, vomiting, constipation, diarrhoea etc.
Pregnancy & Lactation
There are no adequate and well-controlled studies in pregnant women and so Indapa-SR 1.5 mg is not recommended. Mothers taking Indapa-SR 1.5 mg should not breast feed.
Precautions & Warnings
Monitoring of potassium and uric acid serum levels is recommended, especially in subjects with a predisposition or sensitivity to hypokalemia and in patients with gout. Although no allergic manifestations have been reported during clinical trials, patients with a history of allergy to sulfonamide derivatives should be closely monitored.
Overdose Effects of Indapa-SR 1.5 mg
Symptoms: These could include: allergies, skin rashes, epigastric pain, nausea, photosensitivity, dizziness, weakness and paraesthesia.Treatment: Treatment is supportive and symptomatic, directed at correcting the electrolyte abnormalities.
Storage Conditions
Store in a cool and dry place. Protect from light and moisture.
Drug Classes
Thiazide diuretics & related drugs
Mode Of Action
Indapa-SR 1.5 mg is a diuretic antihypertensive. It appears to cause vasodilation, probably by inhibiting the passage of calcium and other ions (sodium, potassium) across membranes. It has an extra-renal antihypertensive action resulting in a decrease in vascular hyperreactivity and a reduction in total peripheral and arteriolar resistance.
Pregnancy
There are no adequate and well-controlled studies in pregnant women and so Indapa-SR 1.5 mg is not recommended. Mothers taking Indapa-SR 1.5 mg should not breast feed.
Frequently Asked Questions
What is Indapa-SR 1.5 mg used for?
Indapa-SR 1.5 mg is indicated in the treatment of essential hypertension . It is effective in treating hypertension in patients with renal function impairment, although its diuretic effect is reduced. Indapa-SR 1.5 mg is also indicated for the treatment of salt and fluid retention associated with congestive heart failure.
What is the dosage of Indapa-SR 1.5 mg?
One tablet daily preferably in the morning. In more sever case Indapa-SR 1.5 mg can be combine with other categories of anti-hypertensive agent. The safety and effectiveness in pediatric patients have not been established
What are the side effects of Indapa-SR 1.5 mg?
Side effects of Indapa-SR 1.5 mg include headache, anorexia, gastric irritation,nausea, vomiting, constipation, diarrhoea etc.
Who should not take Indapa-SR 1.5 mg?
This drug must not be taken in the following conditions: Hypersensitivity to sulfonamides Severe renal failure Hepatic encephalopathy or severe hepatic failure Hypokalaemia
What precautions should be taken with Indapa-SR 1.5 mg?
Monitoring of potassium and uric acid serum levels is recommended, especially in subjects with a predisposition or sensitivity to hypokalemia and in patients with gout. Although no allergic manifestations have been reported during clinical trials, patients with a history of allergy to sulfonamide derivatives should be closely monitored.
Is Indapa-SR 1.5 mg safe during pregnancy and breastfeeding?
There are no adequate and well-controlled studies in pregnant women and so Indapa-SR 1.5 mg is not recommended. Mothers taking Indapa-SR 1.5 mg should not breast feed.
Disclaimer
The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.