Keto-A100 mg
Suppository
Medicine overview
Indications of Keto-A 100 mg
Theropeutic Class
Pharmacology
Keto-A 100 mg is a non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic actions.
Keto-A 100 mg is rapidly and almost completely absorbed from the GI tract.
It is approximately 99% bound to plasma protein, mainly albumin.
Following single or multiple oral doses in healthy adults, the elimination half-life of the drug has averaged 1.1-4 hours. It is rapidly and extensively metabolized in the liver, principally via conjugation with glucoronic acid. The elimination half-life is approximately 1.88 hour.
Following single or multiple oral doses in healthy adults, the elimination half-life of the drug has averaged 1.1-4 hours. Following a single oral dose of Keto-A 100 mg in healthy adults, about 50-90% of the drug is excreted in urine and about 1-8% in faeces within 1-5 days ; most urinary excretion occurs within 12-24 hours and most faecal excretion occurs within 24-48 hours. The elimination half-life is approximately 1.88 hour.
Dosage & Administration of Keto-A 100 mg
| Condition | Dosage | Notes |
|---|---|---|
| Keto-A 100 mg Tablet | Oral treatment with Keto-A 100 mg is 50-100 mg daily, taken with food to minimize gastrointestinal disturbance | For rheumatic disease, 100-200 mg daily in 2-4 divided doses with food. For pain and dysmenorrhoea, 50 mg up to 3 times daily |
| Keto-A 100 mg SR Capsule | 100-200 mg once daily, depending on patient’s weight and on severity of symptomsKeto-A 100 mg IM injection: Adults: 50 to 100 mg every four hours, repeated up to a maximum of 200 mg in twenty-four hours for up to 3 days | Following a satisfactory response oral therapy should be instituted with Keto-A 100 mg tablet. It is recommended that the injection should not normally be continued for longer than three days |
| Elderly | As with other medications it is generally advisable in the elderly to begin Keto-A 100 mg therapy at the lower end of the dose range and to maintain such patients on the lowest effective dosage | |
| Paediatric dosage | Not established for intramuscular use | It is not used as intravenous injection |
| Keto-A 100 mg 2.5% Gel | This is to be applied to the painful area twice daily | The gel can be used with an occlusive dressing. Rub gently into the skin to ensure penetration |
| Suppository | 1 suppository (100 mg) late at night supplemented as required with Keto-A 100 mg capsules during daytime | Keto-A 100 mg suppositories are especially appropriate for controlling overnight symptoms (severity of night and morning pain; duration and severity of morning stiffness). Suppositories administered late at night provide more consistent effective control of overnight symptoms than oral medication. Dosage of Keto-A 100 mg must be carefully adjusted according to individual requirements and response, using the lower possible effective dosage. Dosage exceeding 300 mg daily has not been adequately studied and are not recommended |
Interaction of Keto-A 100 mg
Contraindications
Side Effects of Keto-A 100 mg
Pregnancy & Lactation
Precautions & Warnings
Storage Conditions
Use In Special Populations
Frequently Asked Questions
What is Keto-A 100 mg used for?
Ketoprofen is indicated in musculoskeletal and joint disorders such as ankylosing spondylitis, osteoarthritis, and rheumatoid arthritis, in periarticular disorders such as bursitis and tendinitis, in mild to moderate pain such as dysmenorrhoea or postoperative pain, and in other painful and inflammatory conditions such as acute gout or soft tissue disorders.Ketoprofen is used for symptomatic relie…
What is the dosage of Keto-A 100 mg?
Ketoprofen Tablet: Oral treatment with Ketoprofen is 50-100 mg daily, taken with food to minimize gastrointestinal disturbance. For rheumatic disease, 100-200 mg daily in 2-4 divided doses with food. For pain and dysmenorrhoea, 50 mg up to 3 times daily.Ketoprofen SR Capsule: 100-200 mg once daily, depending on patient’s weight and on severity of symptomsKetoprofen IM injection: Adults: 50 to 100 …
What are the side effects of Keto-A 100 mg?
Adverse reactions to Ketoprofen are usually mild and mainly involve the GI tract, particularly upper GI tract. Most Ketoprofen-induced adverse effects occur during the first month of treatment, and the frequency of adverse effects generally decreases with continued therapy. Adverse reactions involving digestive system are dyspepsia, nausea, abdominal pain, diarrhoea, constipation, flatulence, anor…
Who should not take Keto-A 100 mg?
Ketoprofen is contraindicated in patients with known hypersensitivity to the drug. Ketoprofen is contraindicated in patients in whom asthma, urticaria, or other sensitivity reaction is precipitated by aspirins or other NSAIDs, since severe, rarely fatal, anaphylactic reactions to Ketoprofen have been reported in these patients. The risk of potentially serious adverse GI effects should be considere…
What precautions should be taken with Keto-A 100 mg?
Ketoprofen should be used with caution in patients who may be adversely affected by a prolongation of bleeding time (e.g. patients receiving anticoagulant therapy), since the drug may inhibit platelet function. Ketoprofen should be used with caution in patients with heart failure, hypertension, or other conditions associated with fluid retention, since peripheral edema has been observed in some pa…
Is Keto-A 100 mg safe during pregnancy and breastfeeding?
Embryopathic effects have not been recorded with Ketoprofen, but it is recommended to avoid medication during pregnancy. Trace amounts of the drug appear in breast milk and it should not be used during breast feeding unless unavoidable.
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