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Ketoalfa

Ketoalfa600 mg

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Medicine overview

Indications of Ketoalfa 600 mg

Prevention and treatment of damages due to faulty or deficient protein metabolism in chronic kidney disease in connection with a limited dietary protein intake of 40 g/day or less (adult). Usually, this applies to patients whose glomerular filtration rate (GFR) is less than 25 mL/min.

Composition

One film-coated tablet contains: Isoleucine USP 67 mg Leucine USP 101 mg Phenylalanine USP 68 mg Valine USP 86 mg Methionine USP 59 mg Lysine Hydrochloride USP 93.705 mg eq. to Lysine 75 mg Threonine USP 53 mg Tryptophan USP 23 mg Histidine USP 38 mg Tyrosine USP 30 mg

Dosage of Ketoalfa 600 mg

Adult dose (70 kg body weight)
Dosage:4 to 8 tablets three times daily during meals
Notes:The tablets must not be chewed. Ingestion during meals facilitates proper absorption and the metabolization into the corresponding amino acids
Pediatric population
Dosage:No experience has been gained so far with the administration in pediatric patients

Interaction of Ketoalfa 600 mg

Concomitant administration of calcium-containing drugs may cause or aggravate elevated serum calcium levels. Drugs that form hardly soluble compounds with calcium (e.g. tetracyclines, quinolines such as ciprofloxacin and norfloxacin as well as drugs containing iron, fluoride or estramustine) should not be taken at the same time with Amino Acid Keto Analogues to avoid disturbed absorption of the active substances. An interval of at least two hours should elapse between the ingestion of Amino Acid Keto Analogues and these drugs.

Contraindications

Hypersensitivity to the active substances or to any of the excipients, Hypercalcaemia, Disturbed amino acid metabolism.

Side Effects of Ketoalfa 600 mg

Hypercalcaemia (Very Rare), If hypercalcaemia occurs, the intake of vitamin D should be reduced. In case of persisting hypercalcaemia, the dose of Amino Acid Keto Analogues as well as the intake of any other calcium sources has to be reduced.

Precautions & Warnings

The serum calcium level should be monitored regularly Ensure sufficient calorie intake In the presence of hereditary phenylketonuria, attention should be given to the fact that Amino Acid Keto Analogues contains phenylalanine Monitoring of the serum phosphate levels is needed in case of concomitant administration of aluminium hydroxide

Storage Conditions

Store at a temperature not exceeding 30°C in a dry place. Protect from light & moisture.

Drug Classes

Other genito-urinary preparations

Mode Of Action

Amino Acid Keto Analogues tablets are administered for nutrition therapy in chronic kidney disease.

Absorption

Amino Acid Keto Analogues allow the intake of essential amino acids while minimizing the amino-nitrogen intake.

Distribution

The use of Amino Acid Keto Analogues in combination with a very low protein diet allows reducing nitrogen intake while preventing the deleterious consequences of inadequate dietary protein intake and malnutrition.

Pregnancy

There are no adequate data from the use of Amino Acid Keto Analogues in pregnant women. Animal studies do not indicate direct or indirect harmful effects with respect to pregnancy, embryonal/fetal development, parturition or postnatal development. Caution should be exercised when prescribing to pregnant women. No experience has been made so far with the use during lactation.

Frequently Asked Questions

What is Ketoalfa 600 mg used for?

Prevention and treatment of damages due to faulty or deficient protein metabolism in chronic kidney disease in connection with a limited dietary protein intake of 40 g/day or less (adult). Usually, this applies to patients whose glomerular filtration rate (GFR) is less than 25 mL/min.

What is the dosage of Ketoalfa 600 mg?

Adult dose (70 kg body weight): 4 to 8 tablets three times daily during meals. The tablets must not be chewed. Ingestion during meals facilitates proper absorption and the metabolization into the corresponding amino acids.Pediatric population: No experience has been gained so far with the administration in pediatric patients.

What are the side effects of Ketoalfa 600 mg?

Hypercalcaemia (Very Rare), If hypercalcaemia occurs, the intake of vitamin D should be reduced. In case of persisting hypercalcaemia, the dose of Amino Acid Keto Analogues as well as the intake of any other calcium sources has to be reduced.

Who should not take Ketoalfa 600 mg?

Hypersensitivity to the active substances or to any of the excipients, Hypercalcaemia, Disturbed amino acid metabolism.

What precautions should be taken with Ketoalfa 600 mg?

The serum calcium level should be monitored regularly Ensure sufficient calorie intake In the presence of hereditary phenylketonuria, attention should be given to the fact that Amino Acid Keto Analogues contains phenylalanine Monitoring of the serum phosphate levels is needed in case of concomitant administration of aluminium hydroxide

Disclaimer

The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.

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