Indications of Maxsulin 50 Vial 100 IU/ml
Treatment of all type 1 diabetic patient. Treatment for those with type 2 diabetes whose blood sugar cannot be sufficiently controlled by diet or oral hypoglycemic medications. For the initial stabilization of diabetes in people with diabetic ketoacidosis, hyperosmolar non-ketotic syndrome, and during stressful times like serious illnesses and major surgery for people with diabetes. Gestational diabetes treatment.
Composition
Isophane Insulin Human 30/70 Injection with Insulin Human (rDNA) Insulin Human (rDNA) USP 40 IU (equal to 1.388 mg) is present in each milliliter of solution as 30% Soluble Insulin Human (Regular) and 70% Isophane Insulin Human. Isophane Insulin Human 30/70 Injection with Insulin Human (rDNA) Insulin Human (rDNA) USP 100 IU (equal to 3.47 mg) is present in each milliliter of solution as 30% Soluble Insulin Human (Regular) and 70% Isophane Insulin Human. 50/50 Injection of Insulin Human (rDNA) and Isophane Insulin Human (rDNA) USP 100 IU (equal to 3.47 mg) is present in each milliliter of solution as 50% soluble Insulin Human (Regular) and 50% isophane Insulin Human.
Theropeutic Class
Insulin with a Medium Action.
Pharmacology
Human insulin is produced using recombinant DNA technology as Insulin Human (rDNA). It works and is structurally identical to natural insulin. Insulin controls how glucose is metabolized and promotes the absorption and use of glucose by the liver, muscles, and fat. By promoting glycogenesis and preventing gluconeogenesis, it also reduces blood sugar levels. After injection, insulin human (rDNA) 30/70 and insulin human (rDNA) 50/50 begin to work within 30 minutes, reach their peak levels between 2 and 8 hours later, and persist for roughly 24 hours.
Dosage of Maxsulin 50 Vial 100 IU/ml
The average range of total daily insulin requirement for maintenance therapy in type 1 diabetic patients lies between 0.5 and 1.0 IU/kg. In pre-pubertal children it usually varies from 0.7 to 1.0 IU/kg, whereas in insulin resistant cases, e.g. during puberty or due to obesity, the daily insulin requirement may be substantially higher. Initial dosages for type 2 diabetic patients are often lower, e.g. 0.3 to 0.6 IU/kg/day.The dosage form, the dosage and the administration time of the insulin are different due to the individual differences of each patient. In addition, the dosage is also affected by food, working style and exercising intensity. Therefore, patients should use the insulin under doctor's instruction.
Administration of Maxsulin 50 Vial 100 IU/ml
Within 30 minutes of an injection, a meal or snack containing carbs should be had. Subcutaneous injections are given in the upper arm, thigh, buttock, or abdominal wall. More quickly than from other injection locations, the abdominal wall receives a subcutaneous injection. Never inject insulin human (rDNA) 30/70 or insulin human (rDNA) 50/50 intravenously. Getting ready for use:
Sanitize your hands. To evenly mix the solution and see if the insulin looks normal, gently shake or rotate the vial. When using a brand-new vial, remove the plastic protective cap and use an alcohol swab to clean the rubber plug. Add air to your syringe in an amount equal to the required amount of insulin. Inject air by sticking the needle into the vial. Draw the appropriate amount of insulin into the syringe while turning the bottle and syringe upside down. Check to see if there are any bubbles left in the syringe before removing the needle. In that case, hold the syringe upright and tap it to release the air bubbles.
Injection site:
Choose the region of the body with looser-fitting skin, such as the upper arm, thigh, buttock, or abdomen. Choose a location for each injection that is at least 1 cm away from the location of the preceding injection to prevent tissue injury.
Injection method:
Wash the area of the skin where the injection will be made with alcohol. Place the needle so that it forms a 45° angle with the skin. Injecting insulin requires puncturing the skin with a needle. To ensure that the entire dosage is injected, keep the needle subcutaneous for at least 6 seconds. After removing the needle, place mild pressure on the injection site for several seconds. Avoid scratching the injection site.
Interaction of Maxsulin 50 Vial 100 IU/ml
When taking oral contraceptives, thyroid hormone, adrenal cortical hormone, and other medications that can cause blood sugar levels to rise, you may need to take more insulin. Reduced insulin dosage is necessary when using antidepressants such as salicylate, sulfanilamide, and others that have hypoglycemic effects and cause a drop in blood sugar levels.
Contraindications
Patients with hypoglycemia or those who are allergic to insulin or any of the excipients.
Side Effects of Maxsulin 50 Vial 100 IU/ml
The most frequent unfavorable consequence of insulin therapy is hypoglycemia, and its symptoms might strike rapidly. There aren't many occurrences of allergic reactions that cause red, puffy, or itchy skin. It typically goes away after a few days. In rare cases, factors other than insulin, such as disinfectant and improper injection technique, may be to blame for the allergy.
Pregnancy & Lactation
Because insulin cannot cross the placental barrier, there are no limits on using it to treat diabetes during pregnancy. Baby safety is unaffected by the mother's insulin medication.
Precautions & Warnings
Hyperglycemia may result from improper dosing or stopping the medication, particularly in type 1 diabetes. If the insulin dose is excessively high compared to the amount of insulin needed, hypoglycemia could result. Hypoglycemia can result from skipping meals or unexpectedly doing hard physical activity.
Overdose Effects of Maxsulin 50 Vial 100 IU/ml
Hypoglycemia during treatment may result from using too much insulin. Hypoglycemia between mild and moderate may strike suddenly. When hypoglycemia strikes, it is crucial to seek immediate medical attention. If you have hypoglycemia frequently, speak with your doctor about any potential adjustments to your therapy, diet, and/or exercise regimen that may be necessary to help you stay hypoglycemic-free.
Storage Conditions
Keeping in a refrigerator, store between 2 and 8 degrees Celsius. Never freeze. If insulin is being used recently and does not need to be refrigerated, try to keep it in a cool area away from heat and light. The currently-in-use insulin can be stored at room temperature for a month.