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Nervex0.5 mg
Orion Pharma Ltd.
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Medicine overview
Indications of Mecobal 0.5 mg
Mecobal 0.5 mg is indicated in-
Peripheral Neuropathies
Diabetic Neuropathy
Verteberal Syndrome
Nerve Compression Syndrome
Multiple sclerosis
Amyotrophic lateral sclerosis
Parkinson’s disease
Alzheimer’s disease ... Read moreMecobal 0.5 mg is indicated in-
Peripheral Neuropathies
Diabetic Neuropathy
Verteberal Syndrome
Nerve Compression Syndrome
Multiple sclerosis
Amyotrophic lateral sclerosis
Parkinson’s disease
Alzheimer’s disease
Diabetic retinopathy
Entrapment neuropathy
Drug induced neuropathy
Megaloblastic anemia due to Vitamin B12 deficiency
Theropeutic Class
Drugs for Megaloblastic Anemia
Pharmacology
Mecobal 0.5 mg is the neurologically active form of vitamin B12 and occurs as a water-soluble vitamin in the body. It is a cofactor in the enzyme methionine synthase, which functions to transfer methyl groups for the regeneration of methionine from homocysteine. In anaemia, it increases erythrocyte production by promoting nucleic acid synthesis in the bone marrow and by promoting maturation and division of erythrocytes.
Dosage & Administration of Mecobal 0.5 mg
Tablet: The usual adult dosage is 500 mcg tablet three times daily. The dosage should be adjusted according to the age of patient and the severity of symptoms. Injection:
Peripheral neuropathies: The usual adult dosage is 500 mcg Mecobal 0.5 mg administered intramuscularly or intravenously three times a week.The dosage should be adjusted according to the age of patient and the severity of symptoms.
Megaloblastic anemia: The usual adult dosage is 500 mcg Mecobal 0.5 mg administered intramuscularly or intravenously three times a week. After about two months of administration, dosage should be changed to one ampoule equivalent to 500 mcg of Mecobal 0.5 mg every one to three months as maintenance therapy
Dosage of Mecobal 0.5 mg
Tablet: The usual adult dosage is 500 mcg tablet three times daily. The dosage should be adjusted according to the age of patient and the severity of symptoms. Injection:
Peripheral neuropathies: The usual adult dosage is 500 mcg Mecobal 0.5 mg administered intramuscularly or intravenously three times a week.The dosage should be adjusted according to the age of patient and the severity of symptoms.
Megaloblastic anemia: The usual adult dosage is 500 mcg Mecobal 0.5 mg administered intramuscularly or intravenously three times a week. After about two months of administration, dosage should be changed to one ampoule equivalent to 500 mcg of Mecobal 0.5 mg every one to three months as maintenance therapy
Interaction of Mecobal 0.5 mg
Decreased GI tract absorption with neomycin, aminosalicylic acid, H2-blockers and colchicine. Reduced serum concentrations with oral contraceptives. Reduced effects in anaemia with parenteral chloramphenicol.
Contraindications
Hypersensitivity to any component of this product.
Side Effects of Mecobal 0.5 mg
Generally Mecobal 0.5 mg is well tolerated. However, a few side effects like GI discomfort (including anorexia, nausea or diarrhea) & rash may be seen after administration of Mecobal 0.5 mg.
Pregnancy & Lactation
Not recommended during pregnancy & lactation.
Precautions & Warnings
The medicine should not be used for months if there is no response at all after its use for a certain period of time.
Storage Conditions
Oral: Store at room temperature. Protect from moisture and light.Parenteral: Store at room temperature. Do not expose to direct light.
Use In Special Populations
Use in children: Not recommended.
Drug Classes
Drugs for Megaloblastic Anemia
Mode Of Action
Mecobal 0.5 mg is the neurologically active form of vitamin B12 and occurs as a water-soluble vitamin in the body. It is a cofactor in the enzyme methionine synthase, which functions to transfer methyl groups for the regeneration of methionine from homocysteine. In anaemia, it increases erythrocyte production by promoting nucleic acid synthesis in the bone marrow and by promoting maturation and division of erythrocytes.
Pregnancy
Not recommended during pregnancy & lactation.
Pediatric Uses
Use in children: Not recommended.
Frequently Asked Questions
What is Mecobal 0.5 mg used for?
Mecobal 0.5 mg is indicated in- Peripheral Neuropathies Diabetic Neuropathy Verteberal Syndrome Nerve Compression Syndrome Multiple sclerosis Amyotrophic lateral sclerosis Parkinson’s disease Alzheimer’s disease ... Read moreMecobal 0.5 mg is indicated in- Peripheral Neuropathies Diabetic Neuropathy Verteberal Syndrome Nerve Compression Syndrome Multiple sclerosis Amyotrophic lateral sclerosis Par…
What is the dosage of Mecobal 0.5 mg?
Tablet: The usual adult dosage is 500 mcg tablet three times daily. The dosage should be adjusted according to the age of patient and the severity of symptoms. Injection: Peripheral neuropathies: The usual adult dosage is 500 mcg Mecobal 0.5 mg administered intramuscularly or intravenously three times a week.The dosage should be adjusted according to the age of patient and the severity of symptoms…
What are the side effects of Mecobal 0.5 mg?
Generally Mecobal 0.5 mg is well tolerated. However, a few side effects like GI discomfort (including anorexia, nausea or diarrhea) & rash may be seen after administration of Mecobal 0.5 mg.
Who should not take Mecobal 0.5 mg?
Hypersensitivity to any component of this product.
What precautions should be taken with Mecobal 0.5 mg?
The medicine should not be used for months if there is no response at all after its use for a certain period of time.
Is Mecobal 0.5 mg safe during pregnancy and breastfeeding?
Not recommended during pregnancy & lactation.
Disclaimer
The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.