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Mexiderm0.1%
Cream
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Medicine overview
Indications of Mexiderm 0.1%
Mexiderm 0.1% cream or ointment is indicated for the treatment of-
Eczema in children and adults including atopic
Infantile and descoid eczema
Prurigo nodularis
Psoriasis (excluding wide spread plaque psoriasis)
Neurodermatoses including lichen simplex and lichen planus ... Read moreMexiderm 0.1% cream or ointment is indicated for the treatment of-
Eczema in children and adults including atopic
Infantile and descoid eczema
Prurigo nodularis
Psoriasis (excluding wide spread plaque psoriasis)
Neurodermatoses including lichen simplex and lichen planus
Seborrhoic dermatitis
Contact sensitivity reaction
Discoid lupus erythematoses and may be used as adjunct to systemic steroid therapy in generalized erythroderma.
Theropeutic Class
Corticosteroid
Pharmacology
Betamethasone valerate is a potent topical corticosteroid.
Absorption
Topical corticosteroids have antiinflammatory, antipruritic and vasoconstrictive actions when administered.
Distribution
Betamethasone acts by inhibition of phospholipase A2 activity and reduces the formation of prostaglandins and leukotrienes in local tissues.
Dosage & Administration of Mexiderm 0.1%
Apply sparingly to the affected area two or three times daily until improvement occurs, then twice daily or less. The usual maximum duration of therapy is three weeks.
Dosage of Mexiderm 0.1%
Apply sparingly to the affected area two or three times daily until improvement occurs, then twice daily or less. The usual maximum duration of therapy is three weeks.
Interaction of Mexiderm 0.1%
There are no significant drug interactions reported with Betamethasone Cream/Ointment.
Contraindications
Mexiderm 0.1% cream or ointment is contraindicated in the following conditions :
Hypersensitivity to any of the ingredients in the preparation.
Rosaceae & acne vulgaris.
Perioral dermatitis, perianal & genital pruritis.
Viral infections of the skin, e.g. herpes simplex & chicken pox.
Primary infected skin lesions caused by fungi or bacteria.
Dermatoses in children under one year of age.
Side Effects of Mexiderm 0.1%
Common (>1%)
- The following local adverse reactions are more common with the use of high doses
- long term use and with the use of occlusive dressings of Cream/Ointment: dryness
- itching
- burning
- skin thinning
- local irritation
Uncommon
- features of hypercorticolism
- telagiectasia
- striaea
- skin atrophy. hypertrichosis
- change in pigmentation
- secondary infection
Rare / Long-term
- perioral dermatiis
- allergic contact dermatitis
- maceration of the skin
- acneform eruption
- exacerbation of symptoms.
Pregnancy & Lactation
It should not be used extensively in pregnancy.
Precautions & Warnings
Betamethasone Cream/Ointment is usually well tolerated but if signs of hypersensitivity appear, application should be stopped. Long term continuous topical therapy should be avoided where possible, particularly in children as adrenal suppression may occur even without occlusion. When extensive areas are treated, sufficient systemic absorption may occur to produce symptoms of hypercorticolism. This effect is more likely if occlusive dressings are used, or if the treatment is prolonged. The face or other areas of the body may exhibit atrophic changes after prolonged treatment. If applied to the eyelids, care is needed to ensure that the preparation does not enter the eye, as glaucoma might result. Any spread of the infection requires withdrawal of topical corticosteroid therapy.
Storage Conditions
Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.
Drug Classes
Corticosteroid
Mode Of Action
Mexiderm 0.1% BP is a synthetic adrenocorticosteroid, which is glucocorticoid in nature. It is an analog of prednisolone that also possesses a slight degree of mineral corticosteroid activity. Due to its anti-inflammatory, antipruritic and vasoconstrictive activity, it is very effective and suitable for dermatological use. It is absorbed from the skin and inflammation and/or another disease process in the skin increase percutaneous absorption from the skin. Occlusive dressings substantially increase its percutaneous absorption.
Pregnancy
It should not be used extensively in pregnancy.
Frequently Asked Questions
What is Mexiderm 0.1% used for?
Betamethasone Valerate cream or ointment is indicated for the treatment of- Eczema in children and adults including atopic Infantile and descoid eczema Prurigo nodularis Psoriasis (excluding wide spread plaque psoriasis) Neurodermatoses including lichen simplex and lichen planus ... Read moreBetamethasone Valerate cream or ointment is indicated for the treatment of- Eczema in children and adults i…
What is the dosage of Mexiderm 0.1%?
Apply sparingly to the affected area two or three times daily until improvement occurs, then twice daily or less. The usual maximum duration of therapy is three weeks.
What are the side effects of Mexiderm 0.1%?
The following local adverse reactions are more common with the use of high doses, long term use and with the use of occlusive dressings of Cream/Ointment: dryness, itching, burning, skin thinning, local irritation, features of hypercorticolism, telagiectasia, striaea, skin atrophy. hypertrichosis, change in pigmentation, secondary infection, perioral dermatiis, allergic contact dermatitis, macerat…
Who should not take Mexiderm 0.1%?
Betamethasone Valerate cream or ointment is contraindicated in the following conditions : Hypersensitivity to any of the ingredients in the preparation. Rosaceae & acne vulgaris. Perioral dermatitis, perianal & genital pruritis. Viral infections of the skin, e.g. herpes simplex & chicken pox. Primary infected skin lesions caused by fungi or bacteria. Dermatoses in children under one year of age.
What precautions should be taken with Mexiderm 0.1%?
Betamethasone Cream/Ointment is usually well tolerated but if signs of hypersensitivity appear, application should be stopped. Long term continuous topical therapy should be avoided where possible, particularly in children as adrenal suppression may occur even without occlusion. When extensive areas are treated, sufficient systemic absorption may occur to produce symptoms of hypercorticolism. This…
Is Mexiderm 0.1% safe during pregnancy and breastfeeding?
It should not be used extensively in pregnancy.
Disclaimer
The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.