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Azelto100 mg
Ziska Pharmaceuticals Ltd.
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Medicine overview
Indications of Nafodil 100 mg
Naftidrofuryl oxalate is used to treat peripheral vascular disorders (blood circulation problems outside the brain and heart). It is used to treat the following symptoms of these disorders:
Intermittent claudication
Cramps in legs at night
Severe pain in legs while resting (rest pain) ... Read moreNaftidrofuryl oxalate is used to treat peripheral vascular disorders (blood circulation problems outside the brain and heart). It is used to treat the following symptoms of these disorders:
Intermittent claudication
Cramps in legs at night
Severe pain in legs while resting (rest pain)
Pale or blue fngers or toes which get worse when it is cold
Numbness, tingling or burning feelings in fngers or toes (Raynaud’s syndrome or acrocyanosis)
Open sores on the legs or feet (trophic ulcers)
Poor circulation caused by diabetes (diabetic arteriopathy)
To treat gangrene
Dosage of Nafodil 100 mg
One or two Naftidrofuryl oxalate capsules three times daily during meals for a minimum of three months or at the discretion of the physician.
Contraindications
Hypersensitivity to the active substance or to any of the excipients. Patients with a history of hyperoxaluria or recurrent calcium-containing kidney stones.
Side Effects of Nafodil 100 mg
Gastrointestinal disorders (uncommon): Diarrhoea, nausea, vomiting and epigastric pain.
Renal and urinary disorders (very rare): Calcium oxalate kidney stones.
Skin and subcutaneous tissue disorders (uncommon): Skin rash.
Hepatobiliary disorders (rare): Liver damage.
Precautions & Warnings
The administration of Nafodil 100 mg may modify the composition of the urine, promoting the formation of calcium oxalate kidney stones. The administration of Nafodil 100 mg without liquid before going to bed may cause local oesophagitis. Therefore, it is essential to always take the capsule with a sufficient amount of water. Cases of liver damage have been reported.
Overdose Effects of Nafodil 100 mg
Depression of cardiac conduction and convulsions may occur.
Storage Conditions
Store below 25°C. Protect from light & moisture. Keep the medicine out of reach of children.
Drug Classes
5-HT Agonists
Mode Of Action
Naftidrofuryl oxalate possesses a 5HT2-blocking activity and counteracts both the vasoconstrictor effect and the effect promoting platelet aggregation due to serotonin. Naftidrofuryl oxalate has a direct effect on intracellular metabolism. Thus it increases ATP level, decreases lactic acid level in ischemic conditions and enhances the cellular oxidative capacity. Also, Naftidrofuryl oxalate is a powerful spasmolytic agent.
Pregnancy
In the absence of any relevant clinical data, the use of Nafodil 100 mg is not advisable during pregnancy. In the absence of specific data concerning the excretion of the drug in human milk, Nafodil 100 mg should not be used by breastfeeding women.
Frequently Asked Questions
What is Nafodil 100 mg used for?
Naftidrofuryl oxalate is used to treat peripheral vascular disorders (blood circulation problems outside the brain and heart). It is used to treat the following symptoms of these disorders: Intermittent claudication Cramps in legs at night Severe pain in legs while resting (rest pain) ... Read moreNaftidrofuryl oxalate is used to treat peripheral vascular disorders (blood circulation problems outs…
What is the dosage of Nafodil 100 mg?
One or two Naftidrofuryl oxalate capsules three times daily during meals for a minimum of three months or at the discretion of the physician.
What are the side effects of Nafodil 100 mg?
Gastrointestinal disorders (uncommon): Diarrhoea, nausea, vomiting and epigastric pain. Renal and urinary disorders (very rare): Calcium oxalate kidney stones. Skin and subcutaneous tissue disorders (uncommon): Skin rash. Hepatobiliary disorders (rare): Liver damage.
Who should not take Nafodil 100 mg?
Hypersensitivity to the active substance or to any of the excipients. Patients with a history of hyperoxaluria or recurrent calcium-containing kidney stones.
What precautions should be taken with Nafodil 100 mg?
The administration of Nafodil 100 mg may modify the composition of the urine, promoting the formation of calcium oxalate kidney stones. The administration of Nafodil 100 mg without liquid before going to bed may cause local oesophagitis. Therefore, it is essential to always take the capsule with a sufficient amount of water. Cases of liver damage have been reported.
Disclaimer
The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.