Nixcof

Nixcof(100 mg+1.1 mg+14 mg)/5 ml

Syrup

Guaifenesin + Levomenthol + Diphenhydramine

Opsonin Pharma Ltd.

Product Code : 11871
MRP 80.00
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Medicine overview

Indications of Nixcof (100 mg+1.1 mg+14 mg)/5 ml

This syrup is indicated for the relief of cough, associated congestive symptoms and aiding restful sleep

Composition

Each 5 ml syrup contains- Gualfonosln BP 100 mg Levomenthol BP 1.1 mg Diphenhydramine Hydrochlorldo BP 14 mg

Theropeutic Class

Combined cough expectorants

Pharmacology

This preparation is a mixture of expectorant, decongestant and antihistamine. Guaifenesin is an expectorant. It helps to loosen mucus in chest and throat caused by common cold, infections, or allergies. Levomenthol helps to breathe more easily by relieving congestion. Diphenhydramine is an antihistamine that reduces the effects of natural chemical histamine in the body. It is used to treat sneezing, runny nose, watery eyes, hives, skin rash, itching & other cold or allergy symptoms.

Dosage & Administration of Nixcof (100 mg+1.1 mg+14 mg)/5 ml

12 years and above: 10 ml 4 times a day.

Dosage of Nixcof (100 mg+1.1 mg+14 mg)/5 ml

For adults and children over 12 years: 2 teaspoonfuls syrup 4 times a day or as directed by the physicians. Do not take more than 8 teaspoonful syrup in 24 hours.Use in Children & Adolescents: The efficacy and safety of Guaifenesin have not been established in pediatric patients and adolescents.

Interaction of Nixcof (100 mg+1.1 mg+14 mg)/5 ml

This syrup contains Diphenhydramine Hydrochloride and therefore may potentiate the effects of alcohol, and other CNS depressants. As Diphenhydramine Hydrochloride possess some anticholinergic activity, the effects of anticholinergics (e.g. some psychotrophic drugs and atropine) may be potentiated by this product. This may result in tachycardia, mouth dryness, gastrointestinal disturbances (e.g. colic), urinary retention and headache.

Contraindications

This syrup is contraindicated in individuals with known hypersensitivity to the product or any of its components. This medicine should not be administered to patients who have received treatment with MAOIs within last two weeks.

Side Effects of Nixcof (100 mg+1.1 mg+14 mg)/5 ml

This syrup may cause drowsiness, dizziness, nausea and vomiting, gastro-intestinal disturbance, dry mouth, nose and throat difficulty in urination or blurred vision.

Pregnancy & Lactation

There are no specific data on use of this combination during pregnancy & lactation.

Precautions & Warnings

This syrup may cause drowsiness; if affected, individuals should not drive or operate machinery. Diphenhydramine Hydrochloride should not be taken by individuals with narrow-angle glaucoma or symptomatic prostatic hypertrophy. This product should not be used for persistent or chronic cough, such as occurs with asthma, or where cough is accompanied by excessive secretions unless directed by a physician.

Overdose Effects of Nixcof (100 mg+1.1 mg+14 mg)/5 ml

When taken in excess, Guaifenesin may cause renal calculi. Treatment of overdose should be symptomatic and supportive.

Storage Conditions

Store at a temperature not exceeding 30° C in a dry place. Protect from light & moisture. Keep out of the reach of children.

Drug Classes

Combined cough expectorants

Mode Of Action

Guaifenesin is reported to reduce the viscosity of tenacious sputum end is used as an expectorant. Levomenthol has mild local anesthetic and decongestant properties. Diphenhydramine Hydrochloride possesses antitussive, antihistaminic, and anticholinergic properties.

Pregnancy

As with any other medicine, care should be taken In administration during pregnancy. This product has not been associated with adverse effects in the human fetus or suckling infant.
Disclaimer

The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.