
Lopadine600 mcg/sp
Incepta Pharmaceuticals Ltd.

Nasal Spray
Olopatadine is an inhibitor of the release of histamine from the mast cell and a relatively selective histamine H1‐antagonist that inhibits the in vivo and in vitro type 1 immediate hypersensitivity reaction including inhibition of histamine induced effects on human conjunctival epithelial cells.
Olopatadine is devoid of effects on alpha adrenergic, dopamine and muscarinic type 1 and 2 receptors.
Following topical ocular administration in human, olopatadine was shown to have low systemic exposure.
What is Olopan 600 mcg/spray used for?
Olopatadine is indicated for the treatment of ocular itching associated with allergic conjunctivitis.
What is the dosage of Olopan 600 mcg/spray?
0.1% Sterile Eye Drops: One drop in each affected eye two times per day at an interval of 6 to 8 hours. 0.2% Sterile Eye Drops: One drop in the affected eye once a day.0.7% Sterile Eye Drops: One drop in each affected eye once a day.
What are the side effects of Olopan 600 mcg/spray?
Headaches have been reported at an incidence of 7%. The following adverse experiences have been reported in less than 5% of patients: Asthenia, blurred vision, burning or stinging, cold syndrome, dry eye, foreign body sensation, hyperemia, hypersensitivity, keratitis, lid edema, nausea, pharyngitis, pruritus, rhinitis, sinusitis, and taste perversion
Who should not take Olopan 600 mcg/spray?
Olopatadine Hydrochloride ophthalmic solution is contraindicated in persons with a known hypersensitivity to Olopatadine Hydrochloride.
What precautions should be taken with Olopan 600 mcg/spray?
Olopatadine HCl ophthalmic solution should not be used to treat contact lens related irritation. Patients who wear soft contact lenses should be instructed to wait at least ten minutes after instilling Olopatadine Hydrochloride ophthalmic solution before they insert their contact lenses.
Is Olopan 600 mcg/spray safe during pregnancy and breastfeeding?
There are no adequate and well controlled studies in pregnant women. Because animal studies are not always predictive of human responses, this drug should be used in pregnant women only if the potential benefit to the mother justifies the potential risk to the fetus.It is not known whether topical ocular administration could result in sufficient systemic absorption to produce detectable quantities…
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