Rapilog 100 IU/ml3ml pen
SC Injection
Insulin Aspart
Square Pharmaceuticals PLC.
Product Code : 21328
10% Off
Best PriceTk
/
1
Medicine overview
Indications of Rapilog 100 IU/ml 3ml pen
Rapilog 100 IU/ml 3ml pen is a rapid acting human insulin analog indicated to improve glycemic control in adults and children with diabetes mellitus.
Composition
Each ml suspension contains 100 IU (equivalent to 3.50 mg) Rapilog 100 IU/ml 3ml pen (rDNA) BP as 30% soluble Rapilog 100 IU/ml 3ml pen and 70% protamine-crystallised Rapilog 100 IU/ml 3ml pen.
Theropeutic Class
Rapid Acting Insulin
Pharmacology
The primary activity of Rapilog 100 IU/ml 3ml pen is the regulation of glucose metabolism. Rapilog 100 IU/ml 3ml pen bind to the insulin receptors on muscle and fat cells and lower blood glucose by facilitating the cellular uptake of glucose and simultaneously inhibiting the output of glucose from the liver.
Dosage of Rapilog 100 IU/ml 3ml pen
Dosage of Rapilog 100 IU/ml 3ml pen is individual and determined by the physician in accordance with the needs of the patient. In patients with type 2 diabetes, Rapilog 100 IU/ml 3ml pen can be given in mono therapy or in combination with oral antidiabetic drugs when the blood glucose is inadequately controlled with those oral antidiabetic drugs alone. For patients with type 2 diabetes, the recommended starting dose of Rapilog 100 IU/ml 3ml pen is 6 IU at breakfast and 6 IU at dinner (evening meal). Rapilog 100 IU/ml 3ml pen can also be initiated once daily with 12 IU at dinner (evening meal). When using Rapilog 100 IU/ml 3ml pen once daily, it is generally recommended to move to twice-daily when reaching 30 units by splitting the dose into equal breakfast and dinner doses. If twice daily dosing with Rapilog 100 IU/ml 3ml pen results in recurrent daytime hypoglycaemic episodes, the morning dose can be split into morning and lunchtime doses (thrice daily dosing).The dose should not be increased if hypoglycemia occurred within three days. Dose adjustments can be made once a week until target HbA1c is reached. In patients with type 1 diabetes the individual insulin requirement is usually between 0.5 and 1.0 IU/kg/day. Rapilog 100 IU/ml 3ml pen may fully or partially meet this requirement. When transferring a patient from biphasic human insulin to Rapilog 100 IU/ml 3ml pen, start with the same dose and regimen. Then titrate according to individual needs (according to the titration guidelines in table above). Rapilog 100 IU/ml 3ml pen can be used in elderly patients; however there is limited experience with the use of Rapilog 100 IU/ml 3ml pen in combination with OADs in patients older than 75 years.
Administration of Rapilog 100 IU/ml 3ml pen
Administer 5-10 min before meal
Interaction of Rapilog 100 IU/ml 3ml pen
A number of drugs affect glucose metabolism and may require dose adjustment. The following substances may reduce the Insulin as well as Rapilog 100 IU/ml 3ml pen requirements: Oral anti-diabetic products, angiotensin converting enzyme (ACE) inhibitors, disopyramide, fibrates, fluoxetine, monoamine oxidase inhibitors, propoxyphene, pentoxifylline, salicylates and sulfonamide antibiotics. The following substances may increase the Insulin as well as Rapilog 100 IU/ml 3ml pen requirements: Thiazides, glucocorticoids, thyroid hormones, beta-sympathomimetics, growth hormone and danazol. Beta-blockers, clonidine, lithium salts, and alcohol may either potentiate or weaken the blood glucose lowering effect of insulin.
Contraindications
Insulin Rapilog 100 IU/ml 3ml pen is contraindicated-
during episodes of hypoglycemia
in patients with hypersensitivity to Rapilog 100 IU/ml 3ml pen or one of its excipients
Side Effects of Rapilog 100 IU/ml 3ml pen
Side effects of Rapilog 100 IU/ml 3ml pen are hypoglycemia, allergic reactions, injection site reaction, lipodystrophy, pruritus and rash.
Pregnancy & Lactation
Pregnancy category B. There are no restrictions on treatment with Rapilog 100 IU/ml 3ml pen during lactation. Insulin treatment of the nursing mother should not affect the baby. However, dosage may need to be adjusted.
Precautions & Warnings
Dose adjustment and monitoring: Blood glucose should be monitored in all patients treated with insulin. Insulin regimens should be modified cautiously and only under medical supervision.
Overdose Effects of Rapilog 100 IU/ml 3ml pen
A specific overdose for insulin cannot be defined, however, hypoglycaemia may develop over sequential stages if too high doses relative to the patient’s requirement are administered. Mild hypoglycaemic episodes can be treated by oral administration of glucose or sugary products. Severe hypoglycaemic episodes, where the patient has become unconscious, can be treated by glucagon (0.5 to 1 mg) given intramuscularly or subcutaneously. Glucose must also be given intravenously if the patient does not respond to glucagon within 10 to 15 minutes. Upon regaining consciousness administration of oral carbohydrate is recommended for the patient in order to prevent relapse.
Storage Conditions
Store at 2°C to 8°C in a refrigerator. Do not freeze. Protect from light.
Use In Special Populations
Renal Impairment: Decreased dose may be necessary.Hepatic Impairment: Decreased dose may be necessary.
Drug Classes
Rapid Acting Insulin
Mode Of Action
The primary activity of Rapilog 100 IU/ml 3ml pen is the regulation of glucose metabolism. Rapilog 100 IU/ml 3ml pen bind to the insulin receptors on muscle and fat cells and lower blood glucose by facilitating the cellular uptake of glucose and simultaneously inhibiting the output of glucose from the liver.
Pregnancy
Pregnancy category B. There are no restrictions on treatment with Rapilog 100 IU/ml 3ml pen during lactation. Insulin treatment of the nursing mother should not affect the baby. However, dosage may need to be adjusted.
Pediatric Uses
Renal Impairment: Decreased dose may be necessary.Hepatic Impairment: Decreased dose may be necessary.
Disclaimer
The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.