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Rispolux2 mg
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Riscord2 mg
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Medicine overview
Indications of Riscord 2 mg
Riscord 2 mg tablet is indicated for the treatment of acute and chronic schizophrenic psychosesand other psychotic conditionsin which positive symptoms (such as hallucinationsdelusionsthought disturbanceshostilitysuspiciousness)and/or negative symptoms (such as blunted affectemotional and social withdrawalpoverty of speech) are prominent. Riscord 2 mg also alleviate affective symptoms (such as depressionguilt feelings
Theropeutic Class
Atypical neuroleptic drugs
Pharmacology
Riscord 2 mg is a selective monoaminergic antagonist having a high affinity for serotoninergic 5-HT2 and dopaminergic D2 receptors.
Absorption
Riscord 2 mg binds also to alpha1 adrenergic receptors and with lower affinity, to H1 histamine and alpha2 adrenergic receptors.
Distribution
Riscord 2 mg has no affinity for cholinergic receptors.
Metabolism
Riscord 2 mg, as a potent D2 antagonist, improves the positive symptoms of schizophrenia but causes less depression of motor activity.
Excretion
Balanced central serotonin and dopamine antagonism may reduce extrapyramidal side effect liability and extend the therapeutic activity to the negative and affective symptoms of schizophrenia.
Dosage & Administration of Riscord 2 mg
Psychoses
Dosage:2 mg in 1-2 divided doses on 1st day then 4 mg in 1-2 divided doses on second day (Slower titration appropriate in some patients); usual dose range 4-6 mg daily; doses above 10 mg daily only if benefit considered to outweigh risk (max
Notes:16 mg daily). Elderly (or in hepatic or renal impairment) initially 1 mg daily in two divided doses increased in steps of 1-2 mg twice daily. Child under 15 years not recommended
Mania
Dosage:Initially 2 mg once daily increased if necessary in step of 1 mg daily; usual dose range 1-6 mg daily; Elderly (or in hepatic or renal impairment) initially 1 mg daily in two divided doses increased in steps of 1-2 mg twice daily
Schizophrenia
Dosage:Riscord 2 mg should be generally administered at 1 mg BID initially, with increases in increments of 1 mg BID on the second and third day, as tolerated, to a target dose of 3 mg BID by the third day
Notes:Further dosage adjustments, if indicated, should generally occur at intervals of not less than 1 week. When dosage adjustments are necessary, small dose increments or decrements of 1-2 mg are recommended
| Condition | Dosage | Notes |
|---|---|---|
| Psychoses | 2 mg in 1-2 divided doses on 1st day then 4 mg in 1-2 divided doses on second day (Slower titration appropriate in some patients); usual dose range 4-6 mg daily; doses above 10 mg daily only if benefit considered to outweigh risk (max | 16 mg daily). Elderly (or in hepatic or renal impairment) initially 1 mg daily in two divided doses increased in steps of 1-2 mg twice daily. Child under 15 years not recommended |
| Mania | Initially 2 mg once daily increased if necessary in step of 1 mg daily; usual dose range 1-6 mg daily; Elderly (or in hepatic or renal impairment) initially 1 mg daily in two divided doses increased in steps of 1-2 mg twice daily | |
| Schizophrenia | Riscord 2 mg should be generally administered at 1 mg BID initially, with increases in increments of 1 mg BID on the second and third day, as tolerated, to a target dose of 3 mg BID by the third day | Further dosage adjustments, if indicated, should generally occur at intervals of not less than 1 week. When dosage adjustments are necessary, small dose increments or decrements of 1-2 mg are recommended |
Interaction of Riscord 2 mg
Riscord 2 mg May antagonize the effects of levodopa and dopamine agonists. Chronic administration with Carbamazepine reduces plasma clearance of Riscord 2 mg. Chronic administration with Clozapine may decrease the clearance of Riscord 2 mg. Riscord 2 mg may enhance the effects of certain antihypertensives.
Contraindications
Riscord 2 mg is contraindicated in patients with a known hypersensitivity to the product.
Side Effects of Riscord 2 mg
Insomnia, agitation, anxiety, headache, less commonly drowsiness, impaired concentration, fatigue, blurred vision, constipation, nausea and vomiting, dyspepsia, abdominal pain, hyperprolactinaemia, urine incontinence, tachycardia, hypertension, edema, rash, rhinitis, cerebrovascular accident, neurtropenia and thrombocytopenia have been reported.
Pregnancy & Lactation
Pregnancy: Although, in experimental animals, Riscord 2 mg did not show direct reproductive toxicity, some indirect, prolactin- and CNS-mediated effects were observed, No teratogenicity effect of Riscord 2 mg was noted in any study. The safety of Riscord 2 mg for use during human pregnancy has not been established.Lactation: In animal studies, Riscord 2 mg and 9-hydroxyRiscord 2 mg are excreted in the milk. It has been demonstrated that Riscord 2 mg and 9-hydroxyRiscord 2 mg are also excreted in human breast milk. Therefore, women receiving Riscord 2 mg should not breast feed.
Precautions & Warnings
Special precaution should be taken in case of preexisting cardiovascular diseases, discontinue use if signs and symptoms of tardive dyskinesia occur, renal and hepatic impairment, elderly epilepsy, Parkinson's disease and in pregnancy.
Overdose Effects of Riscord 2 mg
Drowsiness, sedation, tachycardia, hypotension, and extrapyramidal symptoms may occur. In case of severe extrapyramidal symptoms, anticholinergic medication should be administered. Close medical supervision and monitoring should continue until the patient recovers. There is no specific antidote to Riscord 2 mg.
Storage Conditions
Store in a cool and dry place, protected from light.
Frequently Asked Questions
What is Riscord 2 mg used for?
Risperidone tablet is indicated for the treatment of acute and chronic schizophrenic psychoses, and other psychotic conditions, in which positive symptoms (such as hallucinations, delusions, thought disturbances, hostility, suspiciousness), and/or negative symptoms (such as blunted affect, emotional and social withdrawal, poverty of speech) are prominent. Risperidone also alleviate affective sympt…
What is the dosage of Riscord 2 mg?
Psychoses: 2 mg in 1-2 divided doses on 1st day then 4 mg in 1-2 divided doses on second day (Slower titration appropriate in some patients); usual dose range 4-6 mg daily; doses above 10 mg daily only if benefit considered to outweigh risk (max. 16 mg daily). Elderly (or in hepatic or renal impairment) initially 1 mg daily in two divided doses increased in steps of 1-2 mg twice daily. Child under…
What are the side effects of Riscord 2 mg?
Insomnia, agitation, anxiety, headache, less commonly drowsiness, impaired concentration, fatigue, blurred vision, constipation, nausea and vomiting, dyspepsia, abdominal pain, hyperprolactinaemia, urine incontinence, tachycardia, hypertension, edema, rash, rhinitis, cerebrovascular accident, neurtropenia and thrombocytopenia have been reported.
Who should not take Riscord 2 mg?
Risperidone is contraindicated in patients with a known hypersensitivity to the product.
What precautions should be taken with Riscord 2 mg?
Special precaution should be taken in case of preexisting cardiovascular diseases, discontinue use if signs and symptoms of tardive dyskinesia occur, renal and hepatic impairment, elderly epilepsy, Parkinson's disease and in pregnancy.
Is Riscord 2 mg safe during pregnancy and breastfeeding?
Pregnancy: Although, in experimental animals, Risperidone did not show direct reproductive toxicity, some indirect, prolactin- and CNS-mediated effects were observed, No teratogenicity effect of Risperidone was noted in any study. The safety of Risperidone for use during human pregnancy has not been established.Lactation: In animal studies, Risperidone and 9-hydroxyrisperidone are excreted in the …
Disclaimer
The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.