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SK-mox125 mg/1.25 ml
Pediatric Drops
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Medicine overview
Indications of SK-mox 125 mg/1.25 ml
nose and throat infections (i.e. otitis mediasinusitistonsillitispharyngitislaryngitis) Lower respiratory tract infections (i.e. pneumoniaacute and chronic bronchitis lung abscessempyemanose and throat infections (i.e. otitis mediasinusitistonsillitispharyngitislaryngitis) Lower respiratory tract infections (i.e. pneumoniaacute and chronic bronchitis lung abscessempyemabronchiectasis) Skin and soft tissue infections (i.e. cellulitiscarbunclesfurunculosisinfected woundsabscess) Genito-urinary tract infections (i.e. pyelonephritiscystitis and urethritis) Venereal disease (i.e. acute uncomplicated gonorrhoea) In dental abscess
Theropeutic Class
Broad spectrum penicillins
Pharmacology
Amoxicillin is a broad spectrum penicillin.
Absorption
Amoxicillin is stable in the presence of gastric acid and is rapidly absorbed after oral administration. After an oral dose, peak plasma concentration of Amoxicillin is reached within 1 to 2 hours.
Distribution
Amoxicillin is widely distributed at varying concentration in body tissues and fluids.
Dosage of SK-mox 125 mg/1.25 ml
Adult
Dosage:250 mg three times daily, increasing up to 500 mg three times daily for severe infections
Children (up to 10 years of age)
Dosage:125 mg three times daily, increasing up to 250 mg three times daily for severe infections
Severe or recurrent purulent respiratory infection
Dosage:3 gm every 12 hours
Otitis media
Dosage:Recommended dose is 1 g three times daily for adult and 40 mg/kg body weight daily in 3 divided doses for children (max
Notes:3 g daily)
Pneumonia
Dosage:Recommended dose is 500-1000 mg three times daily
Dental abscess
Dosage:Recommended dose is 3 gm, repeated after 10-12 hours
Urinary tract infections
Dosage:Recommended dose is 3 gm, repeated after 10-12 hours
Gonorrhoea
Dosage:Single dose of 2-3 gm with Probenecid 1 gm is recommended (Probenecid is contraindicated in children under 2 years)
In renal impairment
Dosage:it may be necessary to reduce the total daily dosage
| Condition | Dosage | Notes |
|---|---|---|
| Adult | 250 mg three times daily, increasing up to 500 mg three times daily for severe infections | |
| Children (up to 10 years of age) | 125 mg three times daily, increasing up to 250 mg three times daily for severe infections | |
| Severe or recurrent purulent respiratory infection | 3 gm every 12 hours | |
| Otitis media | Recommended dose is 1 g three times daily for adult and 40 mg/kg body weight daily in 3 divided doses for children (max | 3 g daily) |
| Pneumonia | Recommended dose is 500-1000 mg three times daily | |
| Dental abscess | Recommended dose is 3 gm, repeated after 10-12 hours | |
| Urinary tract infections | Recommended dose is 3 gm, repeated after 10-12 hours | |
| Gonorrhoea | Single dose of 2-3 gm with Probenecid 1 gm is recommended (Probenecid is contraindicated in children under 2 years) | |
| In renal impairment | it may be necessary to reduce the total daily dosage |
Administration of SK-mox 125 mg/1.25 ml
Reconstituted suspension can be administered by adding the required amount of suspension to milk, fruit juice, water. These preparations should then be taken immediately.
Interaction of SK-mox 125 mg/1.25 ml
Concurrent use of Amoxicillin and Probenecid may result in increased and prolonged blood levels of Amoxicillin. Amoxicillin may affect the gut flora, leading to lower estrogen reabsorption and reduced efficacy of combined oral estrogen/progesterone contraceptives.
Contraindications
Amoxicillin is contraindicated in penicillin hypersensitive patients.
Side Effects of SK-mox 125 mg/1.25 ml
Side effects are mild and transient in nature. This may include diarrhoea, indigestion or occasionally rash. Pseudo-membranous colitis has been reported rarely.
Pregnancy & Lactation
US FDA pregnancy category of Amoxicillin is B. There are, however, no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed. Amoxicillin has been shown to be excreted in human milk. So, caution should be exercised when Amoxicillin is administered to a lactating mother.
Precautions & Warnings
The possibility of superinfections with mycotic or bacterial pathogens should be kept in mind during therapy. If superinfections occur, Amoxicillin should be discontinued and appropriate therapy should be instituted.
Storage Conditions
Keep in a dry place away from light and heat. Keep out of the reach of children.
Reconstitution
Amoxycillin 500 mg Injection:
Intramuscular: Add 2.5 ml water for injection to Amoxycillin 500 mg injection vial.
Intravenous: Dissolve Amoxycillin 500 mg injection in 10 ml water for injection.
Drug Classes
Broad spectrum penicillins
Mode Of Action
Amoxicillin is a broad spectrum penicillin. It is effective against a wide range of Gram-positive and Gram-negative bacteria. It acts through the inhibition of biosynthesis of cell wall. Amoxicillin is stable in the presence of gastric acid and is rapidly absorbed after oral administration. After an oral dose, peak plasma concentration of Amoxicillin is reached within 1 to 2 hours. Amoxicillin is widely distributed at varying concentration in body tissues and fluids.
Pregnancy
US FDA pregnancy category of Amoxicillin is B. There are, however, no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed. Amoxicillin has been shown to be excreted in human milk. So, caution should be exercised when Amoxicillin is administered to a lactating mother.
Frequently Asked Questions
What is SK-mox 125 mg/1.25 ml used for?
Amoxicillin is indicated in the treatment of infections due to susceptible ß-lactamase negative strains of microorganisms. These infections include Ear, nose and throat infections (i.e. otitis media, sinusitis, tonsillitis, pharyngitis, laryngitis) Lower respiratory tract infections (i.e. pneumonia, acute and chronic bronchitis lung abscess, empyema, bronchiectasis) ... Read moreAmoxicillin is ind…
What is the dosage of SK-mox 125 mg/1.25 ml?
Adult: 250 mg three times daily, increasing up to 500 mg three times daily for severe infections.Children (up to 10 years of age) : 125 mg three times daily, increasing up to 250 mg three times daily for severe infections. Severe or recurrent purulent respiratory infection: 3 gm every 12 hours. Otitis media: Recommended dose is 1 g three times daily for adult and 40 mg/kg body weight daily in 3 di…
What are the side effects of SK-mox 125 mg/1.25 ml?
Side effects are mild and transient in nature. This may include diarrhoea, indigestion or occasionally rash. Pseudo-membranous colitis has been reported rarely.
Who should not take SK-mox 125 mg/1.25 ml?
Amoxicillin is contraindicated in penicillin hypersensitive patients.
What precautions should be taken with SK-mox 125 mg/1.25 ml?
The possibility of superinfections with mycotic or bacterial pathogens should be kept in mind during therapy. If superinfections occur, Amoxicillin should be discontinued and appropriate therapy should be instituted.
Is SK-mox 125 mg/1.25 ml safe during pregnancy and breastfeeding?
US FDA pregnancy category of Amoxicillin is B. There are, however, no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, this drug should be used during pregnancy only if clearly needed. Amoxicillin has been shown to be excreted in human milk. So, caution should be exercised when Amoxicillin is administered to a …
Disclaimer
The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.