medEasy MedEasy
Trugain

Trugain5%

Topical Solution

By
MRP ৳ 550.0010% Off
Best PriceTk /
1
Section

Medicine overview

Indications of Trugain 5%

Trugain 5% is indicated in the treatment of androgenic alopecia in males and females and stabilisation of hair loss in patients with androgenic alopecia, and also of alopecia areata.

Theropeutic Class

Other scalp preparations

Pharmacology

Trugain 5% stimulates hair growth by increasing oxygen, blood and nutrients supply to the hair follicle by widening blood vessels and inhibiting androgen hormone to affect hair follicles.

Absorption

Following topical application, an average of about 1.4% of the total applied dose is absorbed from the normal intact scalp. Following cessation of topical dosing, approximately 95% of the systemically absorbed drug is eliminated within 4 days.

Distribution

Serum Trugain 5% levels and systemic effects resulting from the administration of topical Trugain 5% are governed by the drug’s absorption rate through the skin.

Metabolism

Trugain 5% and its metabolites are excreted principally in the urine.

Excretion

Following cessation of topical dosing, approximately 95% of the systemically absorbed drug is eliminated within 4 days. Trugain 5% and its metabolites are excreted principally in the urine.

Dosage & Administration of Trugain 5%

Trugain 5% topical solution is for external use only and should be applied when the hair and scalp are clean and dry. Apply 1 ml (7 sprays) of Trugain 5% topical solution twice daily at 12-hour intervals to the scalp, beginning at the centre of the affected area and spreading the solution out to cover the entire affected area. The total daily application dose should not exceed 2 ml.For the best results, Trugain 5% topical solution should be allowed to remain on the scalp for about 4 hours before washing. The night-time application should be done 2-4 hours before going to bed to allow the solution to dry out. Trugain 5% topical solution should not be massaged into the scalp, but applied lightly. A hair dryer should not be used to speed up the drying of the solution as it may decrease the effectiveness. Trugain 5% topical solution should not be mixed with any hair oil. The drug should not be used more than two times a day, or be taken orally or applied to any other part of the body to avoid the risk of adverse effects and unwanted hair growth. More frequent use or longer application time have no effect on hair growth. In case of missing any daily applications of Trugain 5% topical solution, the patient should continue with the next application.Hands should be washed immediately if Trugain 5% topical solution is applied with the fingertips. Clinical experience with Trugain 5% indicates that twice-daily applications for 4 months or more may be required before there is evidence of hair growth. To arrest hair fall, Trugain 5% topical solution should be used for not less than 45 days. Depending upon the severity of hair loss or type and extent of baldness, particular strength of Trugain 5% topical solution may be selected.

Dosage of Trugain 5%

Trugain 5% topical solution is for external use only and should be applied when the hair and scalp are clean and dry. Apply 1 ml (7 sprays) of Trugain 5% topical solution twice daily at 12-hour intervals to the scalp, beginning at the centre of the affected area and spreading the solution out to cover the entire affected area. The total daily application dose should not exceed 2 ml.For the best results, Trugain 5% topical solution should be allowed to remain on the scalp for about 4 hours before washing. The night-time application should be done 2-4 hours before going to bed to allow the solution to dry out. Trugain 5% topical solution should not be massaged into the scalp, but applied lightly. A hair dryer should not be used to speed up the drying of the solution as it may decrease the effectiveness. Trugain 5% topical solution should not be mixed with any hair oil. The drug should not be used more than two times a day, or be taken orally or applied to any other part of the body to avoid the risk of adverse effects and unwanted hair growth. More frequent use or longer application time have no effect on hair growth. In case of missing any daily applications of Trugain 5% topical solution, the patient should continue with the next application.Hands should be washed immediately if Trugain 5% topical solution is applied with the fingertips. Clinical experience with Trugain 5% indicates that twice-daily applications for 4 months or more may be required before there is evidence of hair growth. To arrest hair fall, Trugain 5% topical solution should be used for not less than 45 days. Depending upon the severity of hair loss or type and extent of baldness, particular strength of Trugain 5% topical solution may be selected.

Interaction of Trugain 5%

Trugain 5% topical solution should not be used along with other topical agents known to alter the stratum corneum barrier such as tretinoin or dithranol, due to the enhanced absorption of Trugain 5%. Although there is no clinical evidence, there exists the theoretical possibility of absorbed Trugain 5% potentiating orthostatic hypotension caused by peripheral vasodilators.

Contraindications

Patients with cardiac abnormalities Children below 18 years of age Patients using occlusive dressings or other medicines on the scalp Patients with red, inflamed infection, or irritated or painful scalp (including psoriasis & sunburn)

Side Effects of Trugain 5%

Commonly encountered side effects in clinical trials with Trugain 5% topical solution were minor dermatological reactions. Dermatitis or hypertrichosis may occur. These incidences may occur in 0.1–5% of patients.

Pregnancy & Lactation

Trugain 5% topical solution should not be used during pregnancy and lactation.

Precautions & Warnings

Trugain 5% topical solution is more likely to cause scalp irritation. If scalp irritation continues or worsen, use of Trugain 5% topical solution should be stopped.

Overdose Effects of Trugain 5%

Increased systemic absorption of Trugain 5% may potentially occur if higher-than-recommended doses of Trugain 5% are applied to larger surface areas of the body or areas other than the scalp. There are no known cases of Trugain 5% overdosage resulting from topical administration of Trugain 5%.Signs and symptoms of Trugain 5% overdosage would primarily be cardiovascular effects associated with sodium and water retention, and tachycardia. Fluid retention can be managed with appropriate diuretic therapy. Clinically significant tachycardia can be controlled by administration of a beta-adrenergic blocking agent.

Storage Conditions

Store at a cool and dry place, protected from light. Keep out of the reach of the children.

Drug Classes

Other scalp preparations

Mode Of Action

Trugain 5% stimulates hair growth by increasing oxygen, blood and nutrients supply to the hair follicle by widening blood vessels and inhibiting androgen hormone to affect hair follicles.Following topical application, an average of about 1.4% of the total applied dose is absorbed from the normal intact scalp. Topical Trugain 5% absorption is increased by increasing the  dose applied, increasing the frequency of dosing and decreasing the barrier function of the stratum corneum. Serum Trugain 5% levels and systemic effects resulting from the administration of topical Trugain 5% are governed by the drug’s absorption rate through the skin. Following cessation of topical dosing, approximately 95% of the systemically absorbed drug is eliminated within 4 days. Trugain 5% and its metabolites are excreted principally in the urine.

Pregnancy

Trugain 5% topical solution should not be used during pregnancy and lactation.

Frequently Asked Questions

What is Trugain 5% used for?

Minoxidil is indicated in the treatment of androgenic alopecia in males and females and stabilisation of hair loss in patients with androgenic alopecia, and also of alopecia areata.

What is the dosage of Trugain 5%?

Minoxidil topical solution is for external use only and should be applied when the hair and scalp are clean and dry. Apply 1 ml (7 sprays) of Minoxidil topical solution twice daily at 12-hour intervals to the scalp, beginning at the centre of the affected area and spreading the solution out to cover the entire affected area. The total daily application dose should not exceed 2 ml.For the best resu…

What are the side effects of Trugain 5%?

Commonly encountered side effects in clinical trials with Minoxidil topical solution were minor dermatological reactions. Dermatitis or hypertrichosis may occur. These incidences may occur in 0.1–5% of patients.

Who should not take Trugain 5%?

Patients with cardiac abnormalities Children below 18 years of age Patients using occlusive dressings or other medicines on the scalp Patients with red, inflamed infection, or irritated or painful scalp (including psoriasis & sunburn)

What precautions should be taken with Trugain 5%?

Minoxidil topical solution is more likely to cause scalp irritation. If scalp irritation continues or worsen, use of Minoxidil topical solution should be stopped.

Is Trugain 5% safe during pregnancy and breastfeeding?

Minoxidil topical solution should not be used during pregnancy and lactation.

Disclaimer

The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.

Home