Aripra

Aripra10 mg

Tablet

Aripiprazole

Incepta Pharmaceuticals Ltd.

Product Code : 1270
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Medicine overview

Indications of Aripra 10 mg

Aripra 10 mg is indicated for- Schizophrenia Schizoaffective disorder Acute manic and mixed episodes associated with Bipolar I Disorder Maintaining efficacy in patients with Bipolar I Disorder who are stabilized

Theropeutic Class

Atypical neuroleptic drugs

Pharmacology

Aripra 10 mg is an atypical antipsychotic that has both dopamine and serotonin receptors activity. It is a partial agonist of dopamine D2 receptors that relieves the symptoms of schizophrenia. It is characterized as a dopamine system stabilizer. It is a potent partial agonist at serotonin 5-HT1A receptors and antagonist at 5-HT2A receptors. This is associated with improvement of depressive, cognitive and negative symptoms.

Dosage & Administration of Aripra 10 mg

For Schizophrenia: 10 to 15 mg, once daily, without regard to food. Dose increment should not be made before 2 weeks, the time needed to achieve steady state.For Bipolar mania: 30 mg, once daily, without regard to food.

Dosage of Aripra 10 mg

For Schizophrenia: 10 to 15 mg, once daily, without regard to food. Dose increment should not be made before 2 weeks, the time needed to achieve steady state.For Bipolar mania: 30 mg, once daily, without regard to food.

Interaction of Aripra 10 mg

Caution should be exercised when aripipazole is taken in combination with other centrally acting drugs and alcohol. Carbamazepine could cause an increase in Aripra 10 mg clearance and lower blood levels. Ketoconazole, quinidine, fluoxetine or paroxetine can inhibit Aripra 10 mg elimination and cause increased blood levels.

Contraindications

Aripra 10 mg is contraindicated in patients who are hypersensitive to it or to any component of this product.

Side Effects of Aripra 10 mg

Headache, constipation, asthenia, nausea, dyspepsia, vomiting, coughing, abdominal pain.

Pregnancy & Lactation

Aripra 10 mg should not be used in pregnancy as no human trial is performed. Patients should be advised not to breast feed an infant if they are taking Aripra 10 mg.

Precautions & Warnings

Aripra 10 mg may be associated with orthostatic hypotension (orthostatic lightheadedness).Aripra 10 mg should be used with caution in patients with known cardiovascular disease (myocardial infarction or ischaemic heart disease, heart failure or conduction abnormalities), cerebrovascular disease, or conditions that would predispose patients to hypotension (dehydration, hypovolemia, and treatment with antihypertensive medications).Seizures occurred in Aripra 10 mg-treated patients. As with other antipsychotic drugs, Aripra 10 mg should be used cautiously in patients with Alzheimer's dementia.Aripra 10 mg is not approved for the treatment of patients with dementia-related psychosis.

Overdose Effects of Aripra 10 mg

Aripra 10 mg at doses up to 1080 mg causes no fatalities. The signs and symptoms observed with Aripra 10 mg overdose included nausea, vomiting, asthenia, diarrhea, and somnolence.

Drug Classes

Atypical neuroleptic drugs

Mode Of Action

Aripra 10 mg is an atypical antipsychotic that has both dopamine and serotonin receptors activity. It is a partial agonist of dopamine D2 receptors that relieves the symptoms of schizophrenia. It is characterized as a dopamine system stabilizer. It is a potent partial agonist at serotonin 5-HT1A receptors and antagonist at 5-HT2A receptors. This is associated with improvement of depressive, cognitive and negative symptoms.

Pregnancy

Aripra 10 mg should not be used in pregnancy as no human trial is performed. Patients should be advised not to breast feed an infant if they are taking Aripra 10 mg.
Disclaimer

The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.