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Popular Pharmaceuticals Ltd.
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Medicine overview
Indications of Arovital
This is intended as a supplement for intravenous nutrition in order to meet the daily requirements of the water soluble vitamins of NPO (nothing by mouth) or surgery patients.
Composition
Each vial contains:
Vitamin B1 (as Thiamine Mononitrate USP) 2.5 mg
Vitamin B2 (as Riboflavin Sodium Phosphate BP) 3.6 mg
Nicotinamide BP 40 mg
Pantothenic Acid (as Dexpanthenol USP) 15 mg
Vitamin B6 (as Pyridoxine Hydrochloride BP) 4 mg
Biotin BP 0.06 mg
Folic Acid BP 0.4 mg
Vitamin B12 (as Cyanocobalamin BP) 0.005 mg
Ascorbic Acid (as Sodium Ascorbate USP) 100 mg
Dosage of Arovital
Adults and children weighing 10 kg or more: 1 vial (10 ml) daily.Children weighing less than 10 kg: should be given 1 ml of the dissolved mixture per kg body weight/day.The contents of one vial are dissolved by the aseptic addition of 10 ml of one of the following:
Water for injection
Fat emulsion 10%
Glucose solution for infusion (5% to 60%)
Normal saline (0.9% Sodium Chloride)
IV Injection may be added to parenteral nutrition admixtures containing carbohydrates, lipids, amino acids, electrolytes and trace elements provided that compatibility and stability have been confirmed.Method of IV Injection Preparation:
Take 10 ml WFI from provided ampoule by a sterile syringe.
Transfer it into the vial & mix gently to dissolve the lyophilized powder.
Pull back all the reconstituted solution by the syringe.
Administer the solution by slow IV injection (at least over 10 minutes).
Interaction of Arovital
Vitamin B6 can reduce the effect of Levodopa. Folic Acid may lower the serum concentration of Phenytoin.
Contraindications
Known hypersensitivity to any of the components, e.g. Thiamine.
Side Effects of Arovital
Allergic reactions may occur in patients hypersensitive to any component of the preparation, e.g. Thiamine.
Precautions & Warnings
When Lyophilized Powder for Infusion is diluted with water-based solutions, the admixture sould be protected from light. This is not necessary if lyophilized powder for infusion is diluted with intralipid because of the protective effect of the fat emulsion.
Overdose Effects of Arovital
No adverse effects of an overdose of water soluble multivitamin have been reported, with exception of cases of extremely high parenteral doses. The possibility of hypervitaminosis A and D should be considered if lyophilized powder for infusion is dissolved in another multivitamin injection.
Storage Conditions
Before reconstitution: Store at below 25°C in a dry place, protected from light. Keep out of reach of children. After reconstitution: The reconstituted preparation should be added to the infusion solution aseptically immediately before the start of the infusion & used within 24 hours.
Drug Classes
Multi-vitamin & Multi-mineral combined preparations
Mode Of Action
This is a sterile, lyophilized powder of water-soluble vitamins for infusion. It contains balanced amount of all the important water soluble vitamins which act as coenzymes of vital enzymes associated with crucial physiological processes, energy metabolism, cell growth and replenishment especially in brain and nerve cells. Vitamin C acts as an antioxidant and helps in collagen formation. Intravenous administration of this combination gives prompt action.
Pregnancy
Animal reproduction studies or clinical investigations during pregnancy have not been carried out with this preparation. However, there are published reports on safe administration of water soluble vitamins in this patient group.
Frequently Asked Questions
What is Arovital used for?
This is intended as a supplement for intravenous nutrition in order to meet the daily requirements of the water soluble vitamins of NPO (nothing by mouth) or surgery patients.
What is the dosage of Arovital ?
Adults and children weighing 10 kg or more: 1 vial (10 ml) daily.Children weighing less than 10 kg: should be given 1 ml of the dissolved mixture per kg body weight/day.The contents of one vial are dissolved by the aseptic addition of 10 ml of one of the following: Water for injection Fat emulsion 10% Glucose solution for infusion (5% to 60%) Normal saline (0.9% Sodium Chloride) IV Injection may b…
What are the side effects of Arovital ?
Allergic reactions may occur in patients hypersensitive to any component of the preparation, e.g. Thiamine.
Who should not take Arovital ?
Known hypersensitivity to any of the components, e.g. Thiamine.
What precautions should be taken with Arovital ?
When Lyophilized Powder for Infusion is diluted with water-based solutions, the admixture sould be protected from light. This is not necessary if lyophilized powder for infusion is diluted with intralipid because of the protective effect of the fat emulsion.
Disclaimer
The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.