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Doxicap100 mg
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Asidox100 mg
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Medicine overview
Indications of Asidox 100 mg
influenzasinusitisbronchitistonsillitistracheitis. Gastrointestinal tract infections: Choleratraveler's diarrheashigella dysenteryinfluenzasinusitisbronchitistonsillitistracheitis. Gastrointestinal tract infections: Choleratraveler's diarrheashigella dysenteryacute intestinal amebiasis. Chlamydial infections: Lympho-granuloma venereumpsittacosistrachoma. Sexually transmitted diseases: Non gonococcal urethritisacute pelvic inflammatory diseaseuncomplicated urethral and endocervical or rectal infectionsgonorrhoeasyphilispyelonephritiscystitis. Other infections: Impetigofurunculosisinclusion conjunctivitisbrucellosistularemiacellulitisacne and Q-fever.
Theropeutic Class
Tetracycline group of drugs
Pharmacology
Asidox 100 mg is a semisynthetic tetracycline antibiotic with broad spectrum activity.
Absorption
It is primarily a bacteriostatic antibiotic. It has a similar spectrum of activity to other tetracyclines but in particular is more active against Staphylococcus aureus and Nocardia. The drug is often active against penicillin-resistant strains of Staphylococcus aureus and against strains of those organisms that are resistant to other Tetracyclines.
Distribution
Certain Gram-negative strains of E. coli, Proteus mirabilis and Klebsiella, which are often resistant to Tetracycline, may be sensitive to Doxycycline. In addition, 70-90% of the various anaerobes are sensitive to Doxycycline and Bacteroides fragilis is more likely to be sensitive to Doxycycline than to other tetracyclines.
Metabolism
Doxycycline is active against most strains of Haemophilus influenzaeand is particularly useful for infections with H. ducreyi, Actinomyces, Brucella and Vibrio cholerae. It is also active against Nocardia, Chlamydia, Mycoplasma and a wide range of Rickettsiae.
Excretion
Doxycycline is active against spirochetes such as Borellia recurrentis, Treponema pallidum and Treponema pertenue. It is also active against Plasmodium falciparum.
Dosage & Administration of Asidox 100 mg
Usual dose
Dosage:200 mg on first day, then 100 mg daily for 7-10 days
Notes:Severe infections (including refractory urinary tract infections): 200 mg daily for 10 days
Acne
Dosage:100 mg daily
Notes:Uncomplicated genital chlamydia, non-gonococcal urethritis: 100 mg twice daily for 7-21 days (14-21 days in pelvic inflammatory disease)
| Condition | Dosage | Notes |
|---|---|---|
| Usual dose | 200 mg on first day, then 100 mg daily for 7-10 days | Severe infections (including refractory urinary tract infections): 200 mg daily for 10 days |
| Acne | 100 mg daily | Uncomplicated genital chlamydia, non-gonococcal urethritis: 100 mg twice daily for 7-21 days (14-21 days in pelvic inflammatory disease) |
Dosage of Asidox 100 mg
Usual dose
Dosage:200 mg on first day, then 100 mg daily for 7-10 days
Notes:Severe infections (including refractory urinary tract infections): 200 mg daily for 10 days
Acne
Dosage:100 mg daily
Notes:Uncomplicated genital chlamydia, non-gonococcal urethritis: 100 mg twice daily for 7-21 days (14-21 days in pelvic inflammatory disease)
| Condition | Dosage | Notes |
|---|---|---|
| Usual dose | 200 mg on first day, then 100 mg daily for 7-10 days | Severe infections (including refractory urinary tract infections): 200 mg daily for 10 days |
| Acne | 100 mg daily | Uncomplicated genital chlamydia, non-gonococcal urethritis: 100 mg twice daily for 7-21 days (14-21 days in pelvic inflammatory disease) |
Administration of Asidox 100 mg
Capsules should be swallowed whole with plenty of fluid during meals while sitting or standing.
Interaction of Asidox 100 mg
Absorption of tetracyclines is impaired by antacid containing aluminium, calcium or magnesium, and iron containing preparation. Absorption of tetracyclines is also impaired by bismuth salicylate. Barbiturates, carbamazepine and phenytoin decrease half-life of doxycycline. Concurrent use of tetracyclines may render oral contraceptive less effective. Patients who are on anticoagulant therapy may require downward adjustment of their anticoagulant dosages. It is advisable to avoid giving tetracyclines in conjunction with penicillin.
Contraindications
Doxycycline is contraindicated to the patients who have shown hypersensitivity to any of the tetracyclines. Doxycycline is contraindicated to the children under 8 years of age. It is also contraindicated to pregnant women and to the lactating mothers.
Side Effects of Asidox 100 mg
Nausea, vomiting, diarrhoea, skin rashes, hemolytic anaemia, eosinophilia may be reported.
Pregnancy & Lactation
Doxycycline should be avoided in pregnant women, because of the risk of both staining and effect on bone growth in the foetus. Doxycyclines enter breast milk, and mothers taking these drugs should not breastfeed their child.
Precautions & Warnings
The use of drugs of the tetracycline class during tooth development (last half of pregnancy, infancy and childhood to the age of 8 years) may cause permanent discoloration of teeth. Tetracyclines drugs, therefore should not be used in this age group.
Storage Conditions
Keep all medicines out of reach of children. Store in a cool and dry place, protected from light.
Use In Special Populations
Neonates and children: Doxycycline may cause permanent discoloration of the teeth and so is contraindicated for neonates and children under 12 years.Elderly: No special precautions are necessary in the elderly.
Drug Classes
Tetracycline group of drugs
Mode Of Action
Asidox 100 mg is a semisynthetic tetracycline antibiotic with broad spectrum activity. It is primarily a bacteriostatic antibiotic. It has a similar spectrum of activity to other tetracyclines but in particular is more active against Staphylococcus aureus and Nocardia. The drug is often active against penicillin-resistant strains of Staphylococcus aureus and against strains of those organisms that are resistant to other Tetracyclines. Certain Gram-negative strains of E. coli, Proteus mirabilis and Klebsiella, which are often resistant to Tetracycline, may be sensitive to Doxycycline. In addition, 70-90% of the various anaerobes are sensitive to Doxycycline and Bacteroides fragilis is more likely to be sensitive to Doxycycline than to other tetracyclines.Doxycycline is active against most strains of Haemophilus influenzaeand is particularly useful for infections with H. ducreyi, Actinomyces, Brucella and Vibrio cholerae. It is also active against Nocardia, Chlamydia, Mycoplasma and a wide range of Rickettsiae. Doxycycline is active against spirochetes such as Borellia recurrentis, Treponema pallidum and Treponema pertenue. It is also active against Plasmodium falciparum.
Pregnancy
Doxycycline should be avoided in pregnant women, because of the risk of both staining and effect on bone growth in the foetus. Doxycyclines enter breast milk, and mothers taking these drugs should not breastfeed their child.
Frequently Asked Questions
What is Asidox 100 mg used for?
Doxycycline Hydrochloride is indicated in the following infections caused by susceptible microorganisms: Respiratory tract infections: Pneumonia, influenza, sinusitis, bronchitis, tonsillitis, tracheitis. Gastrointestinal tract infections: Cholera, traveler's diarrhea, shigella dysentery, acute intestinal amebiasis. ... Read moreDoxycycline Hydrochloride is indicated in the following infections ca…
What is the dosage of Asidox 100 mg?
Usual dose: 200 mg on first day, then 100 mg daily for 7-10 days.Severe infections (including refractory urinary tract infections): 200 mg daily for 10 days. Acne: 100 mg daily. Uncomplicated genital chlamydia, non-gonococcal urethritis: 100 mg twice daily for 7-21 days (14-21 days in pelvic inflammatory disease).
What are the side effects of Asidox 100 mg?
Nausea, vomiting, diarrhoea, skin rashes, hemolytic anaemia, eosinophilia may be reported.
Who should not take Asidox 100 mg?
Doxycycline is contraindicated to the patients who have shown hypersensitivity to any of the tetracyclines. Doxycycline is contraindicated to the children under 8 years of age. It is also contraindicated to pregnant women and to the lactating mothers.
What precautions should be taken with Asidox 100 mg?
The use of drugs of the tetracycline class during tooth development (last half of pregnancy, infancy and childhood to the age of 8 years) may cause permanent discoloration of teeth. Tetracyclines drugs, therefore should not be used in this age group.
Is Asidox 100 mg safe during pregnancy and breastfeeding?
Doxycycline should be avoided in pregnant women, because of the risk of both staining and effect on bone growth in the foetus. Doxycyclines enter breast milk, and mothers taking these drugs should not breastfeed their child.
Disclaimer
The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.