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Bontiv750 mg+50 mg
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Medicine overview
Indications of Bontiv 750 mg+50 mg
This is primarily indicated in conditions like OsteoarthritisRheumatoid arthritisBone & Joint injuries.
Theropeutic Class
Stimulation of Cartilage formation
Pharmacology
Glucosamine is a natural substance produced in the human body and found in certain foods.
Absorption
Glucosamine acts, as a supplement, as a joint lubricant and shock absorber necessary to maintain healthy cartilage and joint function.
Distribution
Diacerein is an anti-inflammatory analgesic and antipyretic drug, indicated specially for the treatment of arthritic conditions.
Metabolism
It directly inhibits IL-1 synthesis and release in vitro and down modulates IL-1 induced activities and relieves Osteoarthritis.
Dosage & Administration of Bontiv 750 mg+50 mg
Adult & Children above 12 years
Dosage:One tablet (Glucosamine Sulphate 750 mg and Diacerein 50 mg) twice daily for 4-12 weeks, taken with food
Creatinine Clearance(CrCl) < 30 ml/min
Dosage:The dose of Diacerein to be reduced
| Condition | Dosage | Notes |
|---|---|---|
| Adult & Children above 12 years | One tablet (Glucosamine Sulphate 750 mg and Diacerein 50 mg) twice daily for 4-12 weeks, taken with food | |
| Creatinine Clearance(CrCl) < 30 ml/min | The dose of Diacerein to be reduced |
Interaction of Bontiv 750 mg+50 mg
There have been no reports of significant drug interactions of Glucosamine with antibiotics/ antidepressants/ antihypertensives/ nitrates/ antiarrythmics/ anxiolytic/ hypoglycemic agents/ antisecretives. But decreased absorption of Diacerein with aluminium and/ or magnesium hydroxide antacids. Increased risk of diarrhea with laxatives, antibiotics. Avoid co-administration with fibres and phytic acids.
Contraindications
There are no known contraindications for Glucosamine. But proven hypersensitivity to Glucosamine is a contraindication. Diabetics are advised to monitor blood glucose levels regularly when taking Glucosamine. No special studies were formed in patients with renal and/or hepatic insufficiency. The toxicological and pharmacokinetic profile of Glucosamine does not indicate limitations for these patients. However, administration to patients with severe hepatic or renal insufficiency should be under appropriate medical supervision. Children should not be supplemented with Glucosamine. Diacerein or to shellfish (e.g., shrimp, crab); who have diabetes, asthma, alcohol dependence or liver disease. While taking the drug complete blood count, liver function and urinalysis should be monitored regularly. Diacerein is contraindicated in pregnancy, lactation and hypersensitivity to anthraquinone derivatives.
Side Effects of Bontiv 750 mg+50 mg
Diarrhea, constipation, epigastric pain, heart burn, nausea, vomiting, headache, skin rashes, drowsiness, intense yellow coloring of urine.
Pregnancy & Lactation
Diacerein is contraindicated in pregnancy and lactation. Glucosamine should not be taken by pregnant women and nursing mothers due to lack of scientific data regarding its effect on fetus and infants.
Precautions & Warnings
Caution should be practiced when administering Glucosamine + Diacerein in those patients who are allergic to Glucosamine and/or Diacerein or to shellfish (e.g., shrimp, crab); who have diabetes, asthma, alcohol dependence or liver disease. Before taking Glucosamine + Diacerein complete blood count, liver function and urinalysis should be monitored regularly.
Overdose Effects of Bontiv 750 mg+50 mg
Diarrhea may occur.
Storage Conditions
Store in a cool & dry place, protect from light & moisture.
Frequently Asked Questions
What is Bontiv 750 mg+50 mg used for?
This is primarily indicated in conditions like Osteoarthritis, Rheumatoid arthritis, Bone & Joint injuries.
What is the dosage of Bontiv 750 mg+50 mg?
Adult & Children above 12 years: One tablet (Glucosamine Sulphate 750 mg and Diacerein 50 mg) twice daily for 4-12 weeks, taken with food. Creatinine Clearance(CrCl) < 30 ml/min: The dose of Diacerein to be reduced.
What are the side effects of Bontiv 750 mg+50 mg?
Diarrhea, constipation, epigastric pain, heart burn, nausea, vomiting, headache, skin rashes, drowsiness, intense yellow coloring of urine.
Who should not take Bontiv 750 mg+50 mg?
There are no known contraindications for Glucosamine. But proven hypersensitivity to Glucosamine is a contraindication. Diabetics are advised to monitor blood glucose levels regularly when taking Glucosamine. No special studies were formed in patients with renal and/or hepatic insufficiency. The toxicological and pharmacokinetic profile of Glucosamine does not indicate limitations for these patien…
What precautions should be taken with Bontiv 750 mg+50 mg?
Caution should be practiced when administering Glucosamine + Diacerein in those patients who are allergic to Glucosamine and/or Diacerein or to shellfish (e.g., shrimp, crab); who have diabetes, asthma, alcohol dependence or liver disease. Before taking Glucosamine + Diacerein complete blood count, liver function and urinalysis should be monitored regularly.
Is Bontiv 750 mg+50 mg safe during pregnancy and breastfeeding?
Diacerein is contraindicated in pregnancy and lactation. Glucosamine should not be taken by pregnant women and nursing mothers due to lack of scientific data regarding its effect on fetus and infants.
Disclaimer
The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.