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Cortisol1%
Ophthalmic Suspension
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Medicine overview
Indications of Cortisol 1%
Prednisolone eye drops is indicated for the treatment of steroid-responsive inflammation of the palpebral and bulbar conjunctiva, cornea and anterior segment of the globe.
Theropeutic Class
Glucocorticoids
Pharmacology
Prednisolone decreases inflammation by inhibition of migration of polymorphonuclear leukocytes and reversal of increased capillary permeability.
Absorption
It suppresses the immune system by reducing the activity and production of the lymphocytes and eosinophils.
Dosage & Administration of Cortisol 1%
Adult
Dosage:Instill one drop into the conjunctival sac two to four times daily
Notes:During the initial 24 to 48 hours, the dosing frequency may be increased if necessary. Care should be taken not to discontinue the therapy before completing the course
Paediatric
Dosage:Safety and effectiveness in pediatric patients have not been established
| Condition | Dosage | Notes |
|---|---|---|
| Adult | Instill one drop into the conjunctival sac two to four times daily | During the initial 24 to 48 hours, the dosing frequency may be increased if necessary. Care should be taken not to discontinue the therapy before completing the course |
| Paediatric | Safety and effectiveness in pediatric patients have not been established |
Dosage of Cortisol 1%
Adult
Dosage:Instill one drop into the conjunctival sac two to four times daily
Notes:During the initial 24 to 48 hours, the dosing frequency may be increased if necessary. Care should be taken not to discontinue the therapy before completing the course
Paediatric
Dosage:Safety and effectiveness in pediatric patients have not been established
| Condition | Dosage | Notes |
|---|---|---|
| Adult | Instill one drop into the conjunctival sac two to four times daily | During the initial 24 to 48 hours, the dosing frequency may be increased if necessary. Care should be taken not to discontinue the therapy before completing the course |
| Paediatric | Safety and effectiveness in pediatric patients have not been established |
Interaction of Cortisol 1%
No significant drug interactions have been reported.
Contraindications
Cortisol 1% is contraindicated in viral diseases of the cornea, conjunctiva and known hypersensitivity to any of the ingredients of this preparation or other corticosteroids.
Side Effects of Cortisol 1%
Elevation of intraocular pressure (IOP) with possible development of glaucoma and infrequent optic nerve damage, posterior subcapsular cataract formation and delayed wound healing. Fungal and viral infections of the cornea are particularly may develop coincidentally with long-term applications of steroid.
Pregnancy & Lactation
Cortisol 1% is pregnancy category C. So, this drug should be used during pregnancy only if clearly needed. It is not known whether topical administration of corticosteroids would result in sufficient systemic absorption to produce detectable quantities in human milk. Because many drugs are excreted in human milk, caution should be exercised when Cortisol 1% is administered to a nursing woman.
Precautions & Warnings
Shake the bottle well before use. Prolonged use of corticosteroids may result in damage to the optic nerve and defects in vision. If this product is used for longer period of time, intraocular pressure should be routinely monitored.
Overdose Effects of Cortisol 1%
A one-time accidental overdose of Prednisolone Ophthalmic Suspension generally will not cause acute problems. Long time overdose may show general side-effects. In accidental overdose sufficient water should be taken to dilute the medication.
Storage Conditions
Store in a cool, dry place and protect from light. Keep out of the reach of children. Protect from freezing. Shake well before using.
Drug Classes
Glucocorticoids
Mode Of Action
Prednisolone decreases inflammation by inhibition of migration of polymorphonuclear leukocytes and reversal of increased capillary permeability. It suppresses the immune system by reducing the activity and production of the lymphocytes and eosinophils.
Pregnancy
Cortisol 1% is pregnancy category C. So, this drug should be used during pregnancy only if clearly needed. It is not known whether topical administration of corticosteroids would result in sufficient systemic absorption to produce detectable quantities in human milk. Because many drugs are excreted in human milk, caution should be exercised when Cortisol 1% is administered to a nursing woman.
Frequently Asked Questions
What is Cortisol 1% used for?
Prednisolone eye drops is indicated for the treatment of steroid-responsive inflammation of the palpebral and bulbar conjunctiva, cornea and anterior segment of the globe.
What is the dosage of Cortisol 1%?
Adult: Instill one drop into the conjunctival sac two to four times daily. During the initial 24 to 48 hours, the dosing frequency may be increased if necessary. Care should be taken not to discontinue the therapy before completing the course. Paediatric: Safety and effectiveness in pediatric patients have not been established.
What are the side effects of Cortisol 1%?
Elevation of intraocular pressure (IOP) with possible development of glaucoma and infrequent optic nerve damage, posterior subcapsular cataract formation and delayed wound healing. Fungal and viral infections of the cornea are particularly may develop coincidentally with long-term applications of steroid.
Who should not take Cortisol 1%?
Prednisolone Acetate is contraindicated in viral diseases of the cornea, conjunctiva and known hypersensitivity to any of the ingredients of this preparation or other corticosteroids.
What precautions should be taken with Cortisol 1%?
Shake the bottle well before use. Prolonged use of corticosteroids may result in damage to the optic nerve and defects in vision. If this product is used for longer period of time, intraocular pressure should be routinely monitored.
Is Cortisol 1% safe during pregnancy and breastfeeding?
Prednisolone Acetate is pregnancy category C. So, this drug should be used during pregnancy only if clearly needed. It is not known whether topical administration of corticosteroids would result in sufficient systemic absorption to produce detectable quantities in human milk. Because many drugs are excreted in human milk, caution should be exercised when Prednisolone Acetate is administered to a n…
Disclaimer
The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.