Indications of Deslorin 2.5 mg/5 ml
Deslorin 2.5 mg/5 ml is indicated for the relief of symptoms associated with seasonal and perennial allergic rhinitis, such as sneezing, nasal discharge & itching, congestion or stuffiness, as well as ocular itching, tearing and redness, itching of palate and coughing. Deslorin 2.5 mg/5 ml is also indicated for ... Read moreDeslorin 2.5 mg/5 ml is indicated for the relief of symptoms associated with seasonal and perennial allergic rhinitis, such as sneezing, nasal discharge & itching, congestion or stuffiness, as well as ocular itching, tearing and redness, itching of palate and coughing. Deslorin 2.5 mg/5 ml is also indicated for the relief of symptoms associated with chronic idiopathic urticaria such as the relief of itching and the size & number of hives.
Theropeutic Class
Non-sedating antihistamines
Pharmacology
Deslorin 2.5 mg/5 ml is a long-acting, tricyclic, non-sedating, selective peripheral histamine H1-receptor antagonist which inhibits the release of pro-inflammatory mediators from human mast cells and basophils.
Dosage & Administration of Deslorin 2.5 mg/5 ml
Pediatric drops :
Child 6 -11 months of age: 2 ml drops once daily
Child 1 -2 years of age: 2.5 ml drops once daily
Syrup:
Child 6-11 months of age: 2 ml once daily
Child 1-5 years of age: 2.5 ml once daily
Child 6-11 years of age: 5 ml once daily
Adults & > 12 years of age: 10 ml once daily
Tablet:
Adults and children 12 years of age and over: 5 mg daily
Dosage of Deslorin 2.5 mg/5 ml
Pediatric drops:
Child 6-11 months of age: 2 ml drops once daily.
Child 1-2 years of age: 2.5 ml drops once daily.
Syrup:
Child 6-11 months of age: 2 ml once daily.
Child 1-5 years of age: 2.5 ml once daily.
Child 6-11 years of age: 5 ml once daily.
Adults & >12 years of age: 10 ml once daily.
Tablet:
Adults and children 12 years of age and over: 1 tablet daily
Interaction of Deslorin 2.5 mg/5 ml
No clinically relevant drug interactions have been reported.
Contraindications
Deslorin 2.5 mg/5 ml is contraindicated in patients having hypersensitivity to this medication or to any of its ingredients or Loratadine.
Side Effects of Deslorin 2.5 mg/5 ml
Less common side effects may include headache, nausea, fatigue, dizziness, pharyngitis, dyspepsia and myalgia.
Pregnancy & Lactation
Pregnancy: There are no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response, Deslorin 2.5 mg/5 ml should be used in pregnancy only if clearly needed. Lactation: Deslorin 2.5 mg/5 ml passes into breast milk. Therefore, a decision should be made whether to discontinue nursing or to discontinue Deslorin 2.5 mg/5 ml, taking into account the importance of the drug to the mother.
Precautions & Warnings
In adult patients with liver or renal impairment: A starting dose of one 5 mg tablet every other day is recommended based on pharmacokinetic data. If the patient has medical or familial history of seizures.
Overdose Effects of Deslorin 2.5 mg/5 ml
No clinically relevant adverse effects have been reported.
Storage Conditions
Store in a cool & dry place, protected from light. Store below 30°C. Keep all medicines out of the reach of children.
Use In Special Populations
Paediatric Use: The safety and effectiveness of Deslorin 2.5 mg/5 ml in pediatric patients under 2 years of age have not been established.Geriatric Use: In general, dose selection for an elderly patient should be cautious, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy.In adult patients with liver or renal impairment: A starting dose of one 5 mg tablet every other day is recommended based on pharmacokinetic data.
Drug Classes
Non-sedating antihistamines
Mode Of Action
Deslorin 2.5 mg/5 ml, the major active metabolite of Loratadine, is a non-sedating; long acting tricyclic histamine antagonist with selective H1-receptor histamine antagonist activity. Deslorin 2.5 mg/5 ml also inhibits histamine release from human mast cell.
Pregnancy
Pregnancy Category C. The safe use of Deslorin 2.5 mg/5 ml during pregnancy has not been established. Therefore, Deslorin 2.5 mg/5 ml is not to be used during pregnancy unless clearly indicated. Deslorin 2.5 mg/5 ml passes into breast milk, therefore a decision should be made whether to discontinue nursing or to discontinue Deslorin 2.5 mg/5 ml taking into account the importance of the drug to the mother.
Pediatric Uses
Recommended in the use in children & adolescents.