Eluxan

Eluxan75 mg

Tablet

Eluxadoline

Ziska Pharmaceuticals Ltd.

Product Code : 5666
MRP 1250.00
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Medicine overview

Indications of Eluxan 75 mg

Eluxan 75 mg is indicated in adults for the treatment of irritable bowel syndrome with diarrhea (IBS-D).

Theropeutic Class

Carboxylic acids and derivatives, Prokinetic drugs

Pharmacology

Eluxan 75 mg is a mu-opioid receptor agonist, kappa opioid receptor agonist & delta opioid receptor antagonist. Eluxan 75 mg works directly in intestine to reduce peristalsis, also makes the nerves in intestine less sensitive to stimulation.

Dosage & Administration of Eluxan 75 mg

The recommended dosage in adults is 100 mg twice daily taken with food.The recommended dosage is 75 mg twice daily taken with food in patients who: are unable to tolerate the 100 mg dose. are receiving concomitant OATP1B1 inhibitors. have mild or moderate hepatic impairment. Discontinue Eluxan 75 mg in patients who develop severeconstipation.If a dose is missed, take the next dose at the regular time; do not take 2 doses at once

Dosage of Eluxan 75 mg

The recommended dosage in adults is 100 mg twice daily taken with food.The recommended dosage is 75 mg twice daily taken with food in patients who: are unable to tolerate the 100 mg dose. are receiving concomitant OATP1B1 inhibitors. have mild or moderate hepatic impairment. Discontinue Eluxan 75 mg in patients who develop severeconstipation.If a dose is missed, take the next dose at the regular time; do not take 2 doses at once

Interaction of Eluxan 75 mg

Oral Contraceptive, Cyclosporine, Probenecid, Rosuvastatin.

Contraindications

Known or suspected biliary duct obstruction, sphincter of oddi disease or dysfunction & pancreatitis.

Side Effects of Eluxan 75 mg

Most common adverse reactions are constipation, nausea andabdominal pain.

Pregnancy & Lactation

Pregnancy: Not established.Lactation: Not established.

Precautions & Warnings

Sphincter of Oddi spasm and Pancreatitis.Patients who should be monitored closely- without a gallbladder with new or worsening abdominal pain with nausea and vomiting with acute biliary pain with liver or pancreatic enzyme elevation

Storage Conditions

Store in a cool & dry place, protect from light. Keep out of the reach of children.

Use In Special Populations

Pediatric Use: Safety and effectiveness in pediatric patients have not been established.Hepatic Impairment: It is contraindicated in patients with severe hepatic impairment.

Drug Classes

Carboxylic acids and derivatives, Prokinetic drugs

Mode Of Action

Eluxan 75 mg is a mu-opioid receptor agonist, kappa opioid receptor agonist & delta opioid receptor antagonist. Eluxan 75 mg works directly in intestine to reduce peristalsis, also makes the nerves in intestine less sensitive to stimulation.

Pregnancy

Pregnancy: Not established.Lactation: Not established.

Pediatric Uses

Pediatric Use: Safety and effectiveness in pediatric patients have not been established.Hepatic Impairment: It is contraindicated in patients with severe hepatic impairment.
Disclaimer

The information provided is accurate to our best practices, but it does not replace professional medical advice. We cannot guarantee its completeness or accuracy. The absence of specific information about a drug should not be seen as an endorsement. We are not responsible for any consequences resulting from this information, so consult a healthcare professional for any concerns or questions.